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T5798Euphorbia Factor L2;大戟因子L2euphorbiafactor L2;千金子素L2|||euphorbiafactor L2|||大戟因子L2
Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.
价 格:¥电议型 号:T5798产 地:中国大陆
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T5535ERK5-IN-2;化合物ERK5-IN-2ERK5-IN-2
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.
价 格:¥电议型 号:T5535产 地:中国大陆
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T4454Traumatic Acid愈伤酸Dodec-2-Enedioic Acid|||2E-Dodecenedioic Acid|||愈伤酸|||Trans-2-Dodecenedioic Acid
Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus.
价 格:¥电议型 号:T4454产 地:中国大陆
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T40214eIF4E-IN-2eIF4E-IN-2eIF4E-IN-2
eIF4E-IN-2 is a highly effective inhibitor of eukaryotic initiation factor 4e (eIF4e). This compound exhibits significant potential in the investigation of eIF4e dependent diseases, particularly in the context of cancer research.
价 格:¥电议型 号:T40214产 地:中国大陆
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T39727ERα degrader-2;ERα降解剂2ERα degrader-2
ERα degrader-2 is a selective and potent estrogen receptor (SERD) degrader with anticancer activity, inhibits ERα, and has an EC50 value for estrogen receptor degradation of 0.3 nM.ERα degrader-2 can be used for the prevention and treatment of HER-positive breast cancer.
价 格:¥电议型 号:T39727产 地:中国大陆
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T39361Thalidomide-O-amido-C6-NH2;Thalidomide-O-amido-C6-NH2E3LigaseLigand-LinkerConjugates25|||Cereblon Li
Thalidomide-O-amido-C6-NH2 (Cereblon Ligand-Linker Conjugates 11) is a Thalidomide-based synthetic E3 ligase ligand-linker conjugate, comprising of a cereblon ligand and a linker. This compound is employed in the production of PROTACs (proteolysis-targeting chimeras).
价 格:¥电议型 号:T39361产 地:中国大陆
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T38774E67-2E67-2E67-2
E67-2, a derivative of E67, is a low-toxicity, selective inhibitor of the KIAA1718 Jumonji domain. It has an IC 50 value of 3.4 μM. E67-2 specifically inhibits the Jumonji demethylase for histone H3 lysine 9 (H3K9) and histone H3 lysine 4 (H3K4) demethylase.
价 格:¥电议型 号:T38774产 地:中国大陆
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T38669endo-BCN-PEG2-NH2;endo-BCN-PEG2-NH2endo-BCN-PEG2-NH2;endo-BCN-PEG2-NH2
endo-BCN-PEG2-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T38669产 地:中国大陆
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T37871Octaethylene glycol monododecyl ether;C12E8Octaethylene glycol monododecyl ether
C12E8 is a nonionic surfactant formed by the ethoxylation of dodecanol, yielding a compound with eight repeated units of ethylene glycol. It can be used for solubilization of membrane-bound proteins.
价 格:¥电议型 号:T37871产 地:中国大陆
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T37020Endosidin-2;化合物Endosidin-2ES2|||Endosidin 2;ES2|||Endosidin 2
Endosidin-2 is an exocyst inhibitor, a cell-permeable benzylidene benzoylhydrazine, that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 μM, EXO70A1).Endosidin-2 disrupts protein translocation between the endosomes and plasma membrane, thereby facilitating translocation of proteins to the vesicle for degradation. It also inhibits recirculation of endocytosed transferrin to the plasma membrane in HeLa cells and targets multiple isoforms of mammalian E
价 格:¥电议型 号:T37020产 地:中国大陆
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T36651Anti-MERS-2E6 mAb;Anti-MERS-2E6 mAbAnti-MERS-2E6 mAb;Anti-MERS-2E6 mAb
Anti-MERS-2E6 mAb (MERS-2E6), a human IgG1 neutralizing antibody, is expressed in CHO cells. It effectively competes with the virus Spike protein for binding to the CD26 receptor, consequently inhibiting viral invasion into host cells.
价 格:¥电议型 号:T36651产 地:中国大陆
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T3625Bempedoic acid;化合物ETC1002ETC1002|||ESP-55016|||ETC 1002|||ETC-1002;ETC1002|||ESP-55016|||ETC 1002|||
Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic acid(ETC1002) is absorbed rapidly in the small intestine and enters the liver through cell surface receptors different from those transporters that selectively take up statins. Bempedoic acid(ETC1002) is a regulator of lipid and carbohydrate metabolism.
价 格:¥电议型 号:T3625产 地:中国大陆
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T35994Erastin2;Erastin2Erastin2;Erastin2
Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.[1] [2] It inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 µM).[2] It induces cell death in HAP1 cells when used at a concentration of 5 µM, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 or deferoxamine . [1] Erastin2 also induces ferroptotic cell death in HT-1080 cells (EC50 = 0.15 µM), an effect that can be blocked by the reducing agent β-merc
价 格:¥电议型 号:T35994产 地:中国大陆
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T35991ent-Prostaglandin E2;ent-Prostaglandin E2ent-Prostaglandin E2;ent-Prostaglandin E2
Enzymatically-derived prostaglandin E2 (PGE2) is an optically pure compound whereas PGE2 derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGE2 is the opposite enantiomer of PGE2. Significant amounts of racemic PGE2 (rac-PGE2) are generated in vitro and in vivo in settings of oxidative stress via the isoprostane pathway. A proposed mechanism for the formation of rac-PGE2 involves the base catalyzed equilibration from 15-E2t-isoprostane (8-iso-PGE2), g
价 格:¥电议型 号:T35991产 地:中国大陆
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T34392Rosonabant;化合物 T34392E 6776|||E-6776|||E6776;E 6776|||E-6776|||E6776
Rosonabant (E-6776)is a CB1 receptor antagonist/reverse agonist that is studying as an appetite suppressant for the treatment of obesity.
价 格:¥电议型 号:T34392产 地:中国大陆
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T33890PBB3;化合物 T33890PBB-3|||J3.303.052E|||PBB 3;PBB-3|||J3.303.052E|||PBB 3
PBB3 is a tau-specific PET tracer.
价 格:¥电议型 号:T33890产 地:中国大陆
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T31732Evogliptin HCl;化合物 T31732Evogliptin hydrochloride|||DA 1229|||DA1229|||Evogliptin|||DA-1229;Evoglipt
Evogliptin(DA-1229) is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor) that can improve insulin resistance and delays the onset of diabetes. Evogliptin delays the onset of diabetes in young db/db mice and improves insulin sensitivity in HF mice.
价 格:¥电议型 号:T31732产 地:中国大陆
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T31712Ethyl Red lithium;化合物 T31712Ethyl Red lithium
Ethyl Red lithium is a bioactive chemical.
价 格:¥电议型 号:T31712产 地:中国大陆
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T31692Ethanol, 2-(5-(p-aminophenoxy)pentyloxy)-;化合物 T31692Ethanol, 2-(5-(p-aminophenoxy)pentyloxy)-
Ethanol, 2-(5-(p-aminophenoxy)pentyloxy)- is a bioactive chemical.
价 格:¥电议型 号:T31692产 地:中国大陆
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T31662EPZ028862;化合物 T31662EPZ 028862|||EPZ-028862;EPZ 028862|||EPZ-028862
EPZ028862 is a
价 格:¥电议型 号:T31662产 地:中国大陆