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T35336Furosemide sodium
Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema.
价 格：￥电议型 号：T35336产 地：中国大陆
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TP1942L1pep2-AVKI acetate(1315378-69-8 free base)pep2AVKI acetate(1315378698 free base),pep2 AVKI acetate(13
Inhibitor peptide that selectively disrupts binding of the AMPA receptor subunit GluA2 (at the C-terminal PDZ site) to protein interacting with C kinase (PICK1). Does not affect binding of GluA2 to GRIP or ABP and does not increase AMPA current amplitude or affect long term depression (LTD).
价 格：￥电议型 号：TP1942L1产 地：中国大陆
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TN1853Lariciresinolinhibit,Inhibitor,Lariciresinol
Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel antifungal agent for the treatment of fungal infectious diseases in humans. Dietary lariciresinol can attenuate mammary tumor growth and reduce blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats.
价 格：￥电议型 号：TN1853产 地：中国大陆
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T6535Histamine PhosphateHistamine,inhibit,Inhibitor,Histamine Phosphate,Histamine Receptor
Histamine acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors.
价 格：￥电议型 号：T6535产 地：中国大陆
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T21714BMS453Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X
BMS453, a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
价 格：￥电议型 号：T21714产 地：中国大陆
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T10773CF53CF-53,CF53
CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo.
价 格：￥电议型 号：T10773产 地：中国大陆
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TQ0127NavtemadlinNavtemadlin,MDM-2/p53,inhibit,Ubiquitin ligase,Ubiquitin activating enzyme,E3 ligating en
AMG 232 is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM). It binds to MDM2 with a Kd of 0.045 nM.
价 格：￥电议型 号：TQ0127产 地：中国大陆
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T9320YK-3-237YK3237,inhibit,Sirtuin,p53,breast,cancer,triple-negative,mtp53,Mutant,TNBC,Inhibitor,deacety
YK-3-237 reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells carrying mtp53.
价 格：￥电议型 号：T9320产 地：中国大陆
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T6753AI-10-49inhibit,AI 10 49,AI1049,Inhibitor
AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.
价 格：￥电议型 号：T6753产 地：中国大陆
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TP2106LUrantide acetate(669089-53-6 free base)Urantide acetate(669089536 free base),Urantide acetate(669089
Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. Exhibits no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Behaves as a partial agonist in a calcium mobilization assay (in CHO cells expressing hUT receptors).
价 格：￥电议型 号：TP2106L产 地：中国大陆
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TP1253Argirelineskin-permeable,BoNTs,inhibit,neurotransmitter,Inhibitor,peptide,Acetyl hexapeptide 3,Argir
Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity[1][2][3].
价 格：￥电议型 号：TP1253产 地：中国大陆
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T29114VRT-532
VRT-532 is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag) in cystic fibrosis, and modification of CFTR by small molecule modulator VRT-532 can increase ARSB and reduce the accumulation of 4-chondroitin sulfate.
价 格：￥电议型 号：T29114产 地：中国大陆
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TP1666LKisspeptin-10, rat acetate(478507-53-8 free base)Kisspeptin10, rat acetate(478507538 free base),Kiss
Endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54).
价 格：￥电议型 号：TP1666L产 地：中国大陆
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T6153IcotinibIcotinib,Inhibitor,BPI2009,BPI 2009,ErbB-1,HER1,inhibit,EGFR,Epidermal growth factor recepto
Icotinib is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.
价 格：￥电议型 号：T6153产 地：中国大陆
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T8553BC-1471IL-1β,Inhibitor,STAM-binding protein,inhibit,BC-1471,BC1471,DUBs,STAMBP,NALP7,BC 1471,Deubiqu
BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits inflammasome activity of NALP7 (NACHT, LRR and PYD domains-containing protein 7) [1].
价 格：￥电议型 号：T8553产 地：中国大陆
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T7378BRD9539Histone Methyltransferase,chromatin,PRC2,BRD9539,G9a,senescent,BRD-9539,BRD 9539,inhibit,H3K9
BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μM
价 格：￥电议型 号：T7378产 地：中国大陆
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T12531PQCAPQCA
PQCA is a highly selective muscarinic M1 receptor positive allosteric modulator(EC50 value of 49 nM and 135 nM on rhesus and human M1 receptor, respectively).
价 格：￥电议型 号：T12531产 地：中国大陆
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TP1943L1pep2-EVKI acetate(1315378-67-6 free base)pep2EVKI acetate(1315378676 free base),pep-2-EVKI acetate(1
Pep2-EVKI acetate is a cell-permeable peptide. Pep2-EVKI acetate interferes the interaction between protein interacting with C-kinase (PICK1) and GluR2 AMPA receptor subunits.
价 格：￥电议型 号：TP1943L1产 地：中国大陆
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T23535LXanthine amine congener trihydrochlorideXanthine amine congener trihydrochloride
Xanthine amine congener trihydrochloride is a potent adenosine antagonist that reverses the reduction in urine flow, sodium excretion and heart rate produced by the adenosine agonist, N6-cyclohexyladenosine.
价 格：￥电议型 号：T23535L产 地：中国大陆
