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产品数:86101
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T6953Prilocainelocal,anaesthetize,inhibit,Inhibitor,Sodium potassium pump,Na(+),K(+),neurotoxic,Na+/K+ AT
Prilocaine is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures.
价 格:¥电议型 号:T6953产 地:中国大陆
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T8473MLS000532223GTPases,Inhibitor,MLS-000532223,MLS 000532223,MLS000532223,Rab,cytoskeleton,actin,Rho GT
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).
价 格:¥电议型 号:T8473产 地:中国大陆
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T7414ARS-853ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,c
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
价 格:¥电议型 号:T7414产 地:中国大陆
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T5372L-SelenoMethionineselenium,peroxidase,glutathione,dietary,L-SelenoMethionine,Apoptosis,cancer,L Sele
L-Selenomethionine is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.
价 格:¥电议型 号:T5372产 地:中国大陆
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T7053p-Hydroxycinnamic acidInhibitor,Prostaglandin Receptor,p Hydroxycinnamic acid,p-Hydroxycinnamic acid
p-Hydroxycinnamic acid can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.
价 格:¥电议型 号:T7053产 地:中国大陆
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T25538Iperoxo
Iperoxo is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.
价 格:¥电议型 号:T25538产 地:中国大陆
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T13253UmibecestatBACE,Beta-secretase,inhibit,CNP-520,β-Secretase,CNP 520,Inhibitor
Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer´s disease.
价 格:¥电议型 号:T13253产 地:中国大陆
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T8753LX-2761 intermediateLX 2761 intermediate,LX2761 intermediate
LX-2761 intermediate a chemical compound.
价 格:¥电议型 号:T8753产 地:中国大陆
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T63536Dual FAAH/sEH-IN-1
Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
价 格:¥电议型 号:T63536产 地:中国大陆
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T25853NBQX DisodiumNBQX Disodium
NBQX Disodium is a selective and competitive AMPA receptor antagonist.
价 格:¥电议型 号:T25853产 地:中国大陆
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T25310Dersimelagon
Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation.
价 格:¥电议型 号:T25310产 地:中国大陆
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TP1427LReACp53 acetateReACp53 acetate
ReACp53 acetate could inhibit p53 amyloid formation and rescue p53 function in cancer cell lines.
价 格:¥电议型 号:TP1427L产 地:中国大陆
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TN1453BruceantinolBruceantinol,inhibit,Inhibitor
Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL.
价 格:¥电议型 号:TN1453产 地:中国大陆
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TP1899L1Hemokinin 1 (human) acetate(491851-53-7 free base)Hemokinin 1 (human) acetate(491851537 free base),H
Hemokinin 1 (human) acetate is an endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.
价 格:¥电议型 号:TP1899L1产 地:中国大陆
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T12069MK-8353SCH 900353,Extracellular signal regulated kinases,Inhibitor,inhibit,MK 8353,SCH-900353,MK-835
MK-8353 is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 nM and 8.8 nM, respectively)
价 格:¥电议型 号:T12069产 地:中国大陆
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TP2334PMX 53 acetate(219639-75-5 free base)PMX 53 acetate(219639755 free base),PMX 53 acetate(219639 75 5
PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2).
价 格:¥电议型 号:TP2334产 地:中国大陆
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T9532MRT-81Smo,Smoothened,human,C3H10T1/2 cells,inhibit,Shh-light2 cells,rodent,BODIPY-cyclopamine,MRT81,
MRT-81 inhibits human and rodent smoothened?Smo?receptors effectively with an IC50?value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer[1].
价 格:¥电议型 号:T9532产 地:中国大陆
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T8353Pamoic acidPamoic acid,GPR35,neuroprotective,Extracellular signal regulated kinases,Inhibitor,inhibi
Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
价 格:¥电议型 号:T8353产 地:中国大陆
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T6S0535Pinoresinol diglucosidePinoresinol diglucoside,inhibit,Inhibitor
1. Pinoresinol diglucoside is a putative α-glucosidase inhibiting compound. 2. Pinoresinol diglucoside is a important antihypertensive compound.
价 格:¥电议型 号:T6S0535产 地:中国大陆
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T35349CU-CPD107CU-CPD-107,CUCPD107,CU CPD107
CU-CPD107是一种选择性的双活性小分子,对TLR8激动剂和ssRNA配体表现出不同的活性。在R848存在的情况下,CU-CPD107是TLR8信号抑制剂 (IC50=13.7 μM)。在ssRNA存在的情况下,CU-CPD107表现出协同激动剂活性,而CU-CPD107单独不能影响TLR8信号转导。
价 格:¥电议型 号:T35349产 地:中国大陆