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T6561Laquinimodinhibit,multiple sclerosis,relapsing remitting,carboxamide,Nuclear factor-kappaB,Apoptosis
Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
价 格:¥电议型 号:T6561产 地:中国大陆
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T8226Cue-lureCuelure,Inhibitor,inhibit,Cue-lure,610841,Cue lure
Pherocon (4-(4-Acetoxyphenyl)-2-butanone) is a standard melon fly attractant
价 格:¥电议型 号:T8226产 地:中国大陆
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T9207LGW406108X(Z/E)GW406108X(Z/E),GW-406108X(Z/E)
GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .
价 格:¥电议型 号:T9207L产 地:中国大陆
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T7612ICA 110381inhibit,ICA 110381,Potassium Channel,ICA-110381,KcsA,ICA110381,Inhibitor
ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy
价 格:¥电议型 号:T7612产 地:中国大陆
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TN4619Tridecaneinhibit,Inhibitor,Tridecane
n-Tridecane is both a stress compound released by the brown marmorated stink bugs and an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane.
价 格:¥电议型 号:TN4619产 地:中国大陆
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T15615JND3229JND-3229,JND3229
JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma.
价 格:¥电议型 号:T15615产 地:中国大陆
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TP1561123C4Inhibitor,123C-4,123C4,Ephrin Receptor,inhibit
123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase?EPHA4 (Ki=0.65 μM)[1].
价 格:¥电议型 号:TP1561产 地:中国大陆
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T6726VU0361737Parkinson’s,inhibit,ML128,neuroprotective,Metabotropic glutamate receptors,VU0361737,Inhibi
VU 0361737 is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity at mGlu5 and mGlu8 receptors, and is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.
价 格:¥电议型 号:T6726产 地:中国大陆
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T9461AZ194nociceptive neurotransmission,Inhibitor,CRMP2-Ubc9 interaction,Na+ channels,Na channels,inhibit
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
价 格:¥电议型 号:T9461产 地:中国大陆
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TP1543LG280-9 acetate(156761-76-1 free base)G280 9 acetate(156761 76 1 free base),G-280-9 acetate(156761-76
G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows low total immunogenicity that may be attributable to relatively low affinity of this peptide for the HLA-A2.
价 格:¥电议型 号:TP1543L产 地:中国大陆
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T9849HQ461cyclin K degrader,Cyclin dependent kinase,molecular glue,HQ461,HQ 461,HQ-461,CDK12 substrate ph
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.
价 格:¥电议型 号:T9849产 地:中国大陆
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T60027(+)-OSU 61624((5cyclopropyl3methyl1((methylsulfonyl)methyl)1Hpyrazol4yl)oxy)2,6dimethylbenzonitrile,
4-((5-cyclopropyl-3-methyl-1-((methylsulfonyl)methyl)-1H-pyrazol-4-yl)oxy)-2,6-dimethylbenzonitrile is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.
价 格:¥电议型 号:T60027产 地:中国大陆
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T61813AMPA receptor antagonist-3
AMPA receptor antagonist-3 is an AMPA receptor antagonist (patent US20070027143A1).
价 格:¥电议型 号:T61813产 地:中国大陆
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T9616PD-1/PD-L1-IN-10Lewis,T-lymphocyte,tumor,IFN-γ,Inhibitor,lung,LLC,inhibit,Apoptosis,PD1/PDL1IN10,PD
PD-1/PD-L1-IN-10 is an orally active?PD-1/PD-L1?inhibitor (IC50?of 2.7 nM) with potent anticancer efficacy.
价 格:¥电议型 号:T9616产 地:中国大陆
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T7761Pomalidomide-C2-NH2 hydrochloridePomalidomideC2NH2 hydrochloride,inhibit,Inhibitor,Pomalidomide-C-2-
Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. Pomalidomide-C2-NH2 hydrochloride incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
价 格:¥电议型 号:T7761产 地:中国大陆
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T6461Dapoxetine hydrochlorideBenign,BPH,serotonin reuptake,SERT,sexual disorder,LY210448,SLC6A4,Dapoxetin
Dapoxetine HCl is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
价 格:¥电议型 号:T6461产 地:中国大陆
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T7134MavacamtenMyosin,Inhibitor,inhibit,SAR 439152,SAR-439152,Mavacamten,MYK 461,MYK461
MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
价 格:¥电议型 号:T7134产 地:中国大陆
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T8961GW280264XGW-280264X,inhibit,GIC,Inhibitor,immunotherapy,metalloproteinases,Matrix metalloproteinases
GW280264X is an inhibitor of ADAM17 .
价 格:¥电议型 号:T8961产 地:中国大陆
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TP1120LIRBP acetate(211426-18-5 free base)IRBP acetate(211426185 free base),IRBP acetate(211426 18 5 free b
IRBP(Interphotoreceptor Retinoid Binding Protein Fragment ) acetate is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visual pigment Binding Protein peptide (IRBP 161-180) and can induce post-uveitis (EAU).
价 格:¥电议型 号:TP1120L产 地:中国大陆