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T74879306-N16B;化合物 306-N16B306-N16B
306-N16B is a lipid nanoparticle designed for the systemic co-delivery of Cas9 mRNA and sgRNA, facilitating the transport of mRNA to pulmonary endothelial cells. This compound is advantageous for research focused on genome editing-based therapies [1].
价 格:¥电议型 号:T74879产 地:中国大陆
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T743666BrCaQ-C10-TPP;化合物 6BrCaQ-C10-TPP6BrCaQ-C10-TPP
6BrCaQ-C10-TPP, a potent inhibitor of the mitochondrial heat shock protein TRAP1, exhibits antiproliferative activity against various human cancer cells, with an IC50 range of 0.008-0.30 μM. Additionally, it induces disturbances in mitochondrial membranes [1].
价 格:¥电议型 号:T74366产 地:中国大陆
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T73830BRD4 Inhibitor-16;化合物 BRD4 Inhibitor-16BRD4 Inhibitor-16
BRD4 Inhibitor-16 (Compound 4) is a potent inhibitor of bromodomain 4 (BRD4), whose overexpression is closely correlated with various human cancers through the regulation of histone post-translational modifications. It serves as a valuable tool for explorative studies focused on BRD4 inhibition, facilitating an enhanced comprehension of BRD4 inhibitor release-related information [1].
价 格:¥电议型 号:T73830产 地:中国大陆
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T73444BRD7586;化合物 BRD7586BRD7586
BRD7586 represents the smallest known anti-CRISPR, functioning as a cell-permeable, small-molecule inhibitor targeting SpCas9.
价 格:¥电议型 号:T73444产 地:中国大陆
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T7315BAY1125976;化合物BAY1125976BAY1125976
BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)
价 格:¥电议型 号:T7315产 地:中国大陆
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T72636BRD4 Inhibitor-26;化合物 BRD4 Inhibitor-26BRD4 Inhibitor-26
BRD4 Inhibitor-26, a bromodomain protein 4 (BRD4) inhibitor/nitric oxide-donator, exhibits inhibitory activity against BRD4 (BD1) and BRD4 (BD2) with IC50 values of 0.82 μM and 1.94 μM, respectively. It is utilized in ovarian cancer research.
价 格:¥电议型 号:T72636产 地:中国大陆
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T71265BMS-830216;化合物 BMS-830216BMS-830216
BMS-830216 is a nonbasic melanin hormone receptor 1 antagonist and a prodrug of BMS-819881.
价 格:¥电议型 号:T71265产 地:中国大陆
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T71109BAY-386;化合物 BAY-386BAY-386
BAY-386 is a PAR1 receptor inhibitor which suppresses activation of thrombin and platelet activity.
价 格:¥电议型 号:T71109产 地:中国大陆
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T71075BN 50726;化合物 BN 50726BN 50726
BN 50726 is a platelet activating factor inhibitor; antagonizes PAF receptor binding.
价 格:¥电议型 号:T71075产 地:中国大陆
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T71050U 80816B;化合物 U 80816BU 80816B
U 80816B is a cholinergic direct agonist.
价 格:¥电议型 号:T71050产 地:中国大陆
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T70389BMS986126;化合物 BMS986126BMS986126
BMS-986122 is a IRAK4 Inhibitor. BMS-986126 attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity. BMS-986126 inhibited TLR7- and TLR9-dependent responses using cells derived from lupus patients, suggesting that inhibition of IRAK4 has the potential for therapeutic benefit in treating lupus.
价 格:¥电议型 号:T70389产 地:中国大陆
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T70348BPN-14136;化合物 BPN-14136BPN-14136
BPN-14136 is a potent RBP4 antagonist.
价 格:¥电议型 号:T70348产 地:中国大陆
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T70133BAY-846;化合物 BAY-846BAY-846
BAY-846 is an allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model.
价 格:¥电议型 号:T70133产 地:中国大陆
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T69371BMS 378806;化合物 BMS 378806BMS 378806
BMS-378806 is an orally bioavailable HIV-1 inhibitor that interferes with gp120-CD4 interaction.
价 格:¥电议型 号:T69371产 地:中国大陆
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T68353BVT-74316;化合物 BVT-74316BVT-74316
BVT-74316 is an orally administered antagonist of the serotonin 6 receptor (5-HT6) being developed by Proximagen
价 格:¥电议型 号:T68353产 地:中国大陆
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T68342BTA-EG6;化合物 BTA-EG6BTA-EG6
BTA-EG6 is a novel catalase-amyloid interaction inhibitor, penetrating the blood-brain barrier and protecting cells from Aβ-induced toxicity.
价 格:¥电议型 号:T68342产 地:中国大陆
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T68234BI-831266;化合物 BI-831266BI-831266
BI-831266 is a potent and selective Aurora kinase B inhibitor.
价 格:¥电议型 号:T68234产 地:中国大陆
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T67906Bis(2-methoxy-5-((Z)-3,4,5-trimethoxystyryl)phenyl) hydrogen phosphate;化合物 T67906Bis(2-methoxy-5-((Z
Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1´-(hydrogen phosphate) is a compound that is a phosphoric acid derivative of compound statins.
价 格:¥电议型 号:T67906产 地:中国大陆
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T6778BDA-366;化合物BDA-366BDA-366
BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-apoptotic entity. This compound effectively suppresses lung cancer cell growth[1].
价 格:¥电议型 号:T6778产 地:中国大陆