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T81960Lacto-N-difucohexaose II；化合物 Lacto-N-difucohexaose IILNDFH II|||Lacto-N-fucohexaose；LNDFH II|||Lacto
Lacto-N-difucohexaose II (LNDFH II), an oligosaccharide found in human milk, plays a crucial role in infant health [1].
价 格：￥电议型 号：T81960产 地：中国大陆
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T80960TPT-004；化合物 TPT-004TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating peripheral serotonin [1] and impeding colorectal tumor growth.
价 格：￥电议型 号：T80960产 地：中国大陆
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T80816WAY-329600；化合物 WAY-329600WAY-329600
WAY-329600 is an active molecule.
价 格：￥电议型 号：T80816产 地：中国大陆
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T79960Aloveroside A；化合物 Aloveroside AAloveroside A
Aloveroside A, a triglucosylnaphthalene derivative extracted from Aloe vera using ethanol, exhibits modest inhibitory activity against bACE, demonstrating approximately 18.68% inhibition at a concentration of 100 μg/mL [1].
价 格：￥电议型 号：T79960产 地：中国大陆
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T79609STAT3-IN-18；化合物 STAT3-IN-18STAT3-IN-18
STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and exhibits anti-proliferative properties. It promotes apoptosis by activating caspase-3 and elevating levels of cleaved polyADP-ribose polymerase, in addition to enhancing maturation and antigen presentation in dendritic cells. Moreover, STAT3-IN-18 has demonstrated in vivo safety.
价 格：￥电议型 号：T79609产 地：中国大陆
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T79608DPP；化合物 DPPDPP
DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating antiproliferative activity. It activates caspase-3 and cleaved poly ADP-ribose polymerase, inducing apoptosis. Furthermore, DPP enhances the maturation and antigen presentation of dendritic cells and exhibits in vivo safety [1].
价 格：￥电议型 号：T79608产 地：中国大陆
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T79607h-NTPDase-IN-2；h-NTPDase抑制剂2hNTPDase-IN-2；hNTPDase-IN-2
h-NTPDase-IN-2 is a broad-spectrum NTPDase inhibitor that inhibits multiple h-NTPDas isoforms.
价 格：￥电议型 号：T79607产 地：中国大陆
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T79606CAF-382；化合物 CAF-382CAF-382
CAF-382 (compound B1), an analog of SNS-032, functions as a CDKL5 and pan-CDK inhibitor, exhibiting modest inhibitory activity against GSK3α/β with an affinity greater than 1.8 μM. It effectively inhibits CDKL5 and impedes the phosphorylation of the CDKL5 E2 domain [1].
价 格：￥电议型 号：T79606产 地：中国大陆
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T79605RIP1 kinase inhibitor 8；化合物 RIP1 kinase inhibitor 8RIP1 kinase inhibitor 8
RIP1 Kinase Inhibitor 8 (Compound 77), a potent and highly selective dihydropyrazole (DHP) RIP1 kinase inhibitor, exhibits an IC50 of 20 nM and effectively prevents necrotic cell death. It also demonstrates a favorable pharmacokinetic profile across multiple species [1].
价 格：￥电议型 号：T79605产 地：中国大陆
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T79604SHR5428；化合物 SHR5428SHR5428
SHR5428 is an orally active, selective, noncovalent inhibitor of CDK7, displaying potent enzymatic inhibition (IC50 = 2.3 nM) and effectively suppressing cellular activity in triple-negative breast cancer MDA-MB-468 cells (IC50 = 6.6 nM) [1].
价 格：￥电议型 号：T79604产 地：中国大陆
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T796033,7-DMF；化合物 3,7-DMF3,7-DMF
3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation. By inducing antioxidant gene expression and scavenging reactive oxygen species (ROS), 3,7-DMF is useful for researching liver fibrosis [1].
价 格：￥电议型 号：T79603产 地：中国大陆
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T79602MTP；化合物 MTPMTP
MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation. Further, it inhibits JAK2 signaling, rendering it useful for the study of oral squamous cell carcinoma [1].
价 格：￥电议型 号：T79602产 地：中国大陆
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T79601SPC-180002；化合物 SPC-180002SPC-180002
SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively. It disrupts redox homeostasis through ROS generation, consequently enhancing p21 protein stability and inducing mitochondrial dysfunction. Furthermore, this compound significantly impedes cell cycle progression and malignancy proliferation, while also activating the Nrf2 signaling pathway [1].
价 格：￥电议型 号：T79601产 地：中国大陆
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T79600Zharp2-1；化合物 Zharp2-1Zharp2-1
Zharp2-1, a RIPK2 inhibitor, inhibits the transcription of inflammatory cytokines induced by MDP-induced or Listeria monocytogenes infection and alleviates MDP-induced peritonitis symptoms in mice, which can be used for the study of inflammatory bowel disease (IBD).
价 格：￥电议型 号：T79600产 地：中国大陆
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T78960FABP4-IN-2；化合物 FABP4-IN-2FABP4-IN-2
FABP4-IN-2 (Compd 10g), a selective and orally active FABP4 inhibitor, exhibits K i values of 0.51 μM for FABP4 and 33.01 μM for FABP3, demonstrating its specificity towards FABP4. It is utilized in research investigating inflammatory diseases [1].
价 格：￥电议型 号：T78960产 地：中国大陆
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T7815LAOD9604 acetate(221231-10-3 free base)；化合物AOD9604 acetateAOD-9604 acetate|||AOD9604 acetate|||AOD 96
AOD9604 acetate(221231-10-3 free base) is a potential anti-obesity peptide based on the human growth hormone.
价 格：￥电议型 号：T7815L产 地：中国大陆
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T77960Thalidomide-5-O-C13-NH2 hydrochloride；化合物 Thalidomide-5-O-C13-NH2 hydrochlorideThalidomide-5-O-C13-N
Thalidomide-5-O-C13-NH2 hydrochloride, a cereblon ligand derived from Thalidomide, facilitates the recruitment of CRBN protein. It is designed to conjugate with a ligand for protein recruitment through a linker, enabling the formation of PROTACs [1].
价 格：￥电议型 号：T77960产 地：中国大陆
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T77433Feladilimab；菲阿迪利单抗GSK3359609；GSK3359609
Feladilimab (GSK3359609) is an IgG4 monoclonal antibody that is an ICOS agonist. Feladilimab binds to ICOS-expressing T cells, induces IFNγ, and increases PD-1/L1 expression. Feladilimab has anti-tumor activity and can be used to study cancer.
价 格：￥电议型 号：T77433产 地：中国大陆
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T76960Verpasep caltespen；化合物 Verpasep caltespenVerpasep caltespen
Verpasep caltespen (HspE7), a recombinant fusion protein, originates from the Mycobacterium bovis Calmette-Guérin heat shock protein 65 (Hsp65) and is covalently bonded at its C-terminal end to the E7 protein of HPV16. This compound has applications in researching both precancerous and cancerous lesions linked to the human papillomavirus (HPV) [1] [2].
价 格：￥电议型 号：T76960产 地：中国大陆
