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T79883,4-Diaminotoluene;3,4-二氨基甲苯3,4-Diaminotoluene
3,4-Diaminotoluene, an aromatic amine derived from toluene, has been used in the synthesis of a variety of compounds such as polyurethanes, polyureas and polyamides, as well as in the synthesis of amino acids, peptides and proteins. It has also been used in the synthesis of various drugs such as antibiotics and antivirals.
价 格:¥电议型 号:T7988产 地:中国大陆
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T7904SR 19881;化合物SR 19881SR 19881
SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay).
价 格:¥电议型 号:T7904产 地:中国大陆
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T78988A-1293102;化合物 A-1293102A-1293102
A-1293102 is a potent, selective inhibitor of BCL-XL, effective in inducing apoptosis in tumor cells reliant on BCL-XL [1].
价 格:¥电议型 号:T78988产 地:中国大陆
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T78726Z795161988;化合物 Z795161988Z795161988
Z795161988 functions as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase, exhibiting an inhibitory concentration (IC50) of 2.2 μM [1].
价 格:¥电议型 号:T78726产 地:中国大陆
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T78097LMazdutide acetate(2259884-03-0 free base);化合物 Mazdutide acetate(2259884-03-0 free base)Mazdutide ace
Mazdutide acetate is a potent co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR), a gastrin-regulating hormone analog.Mazdutide acetate stimulates insulin secretion from mouse pancreatic islets, and can be used in studies of obesity and type 2 diabetes (T2D).
价 格:¥电议型 号:T78097L产 地:中国大陆
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T77988Phenyl sulfate;化合物 Phenyl sulfatePhenyl hydrogen sulfate;Phenyl hydrogen sulfate
Phenyl sulfate, an orally active metabolite derived from gut microbiota, induces albuminuria and podocyte damage in diabetes experimental models. It serves as a potential disease marker and therapeutic target for diabetic kidney disease [1].
价 格:¥电议型 号:T77988产 地:中国大陆
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T77783WAY-639889;化合物 WAY-639889WAY-639889
WAY-639889 is a small molecule compound with selective and potent inhibitory effects on neuropeptide Y-5 receptors.
价 格:¥电议型 号:T77783产 地:中国大陆
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T77149Cobolimab考伯利单抗TSR-022|||GSK4069889
Cobolimab (TSR-022) is a potent monoclonal antibody to TIM-3. Cobolimab induces internalization of TIM-3 with an IC50 value of 0.4464 nM. Cobolimab has antitumor activity and can be used to study advanced/metastatic melanoma and advanced hepatocellular carcinoma.
价 格:¥电议型 号:T77149产 地:中国大陆
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T76988Tanfanercept;化合物 TanfanerceptTanfanercept
Tanfanercept (HL036337), an anti-TNF-α monoclonal antibody, has shown efficacy in reducing corneal erosions in a dry eye (DE) mouse model [1] [2].
价 格:¥电议型 号:T76988产 地:中国大陆
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T76019[pTyr5] EGFR (988-993) (TFA);化合物 [pTyr5] EGFR (988-993) (TFA)[pTyr5] EGFR (988-993) (TFA)
[pTyr5] EGFR (988-993) TFA, originating from the Tyr992 autophosphorylation site of the epidermal growth factor receptor (EGFR 988-993), frequently forms a complex with catalytically inactive protein-tyrosine phosphate 1B (PTP1B) [1].
价 格:¥电议型 号:T76019产 地:中国大陆
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T75988Dynorphin A (1-10) (TFA);化合物 Dynorphin A (1-10) (TFA)Dynorphin A (1-10) (TFA)
Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, interacts with κ-opioid receptor´s extracellular loop 2 and inhibits NMDA-activated currents with an IC 50 of 42.0 μM.
价 格:¥电议型 号:T75988产 地:中国大陆
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T75651Rivulariapeptolides 988;化合物 Rivulariapeptolides 988Rivulariapeptolides 988
Rivulariapeptolides 988 demonstrates significant potency and selectivity as a serine protease inhibitor, exhibiting IC50 values of 95.46 nM for chymotrypsin, 15.29 nM for elastase, and 85.50 nM for proteinase K [1].
价 格:¥电议型 号:T75651产 地:中国大陆
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T74994SJ988497;化合物 SJ988497SJ988497
SJ988497 is a PROTAC JAK2 degrader that effectively inhibits proliferation in CRLF2-rearranged (CRLF2r) cells and facilitates the degradation of the CRBN neosubstrate GSPT1. Composed of a Ruxolitinib derivative, a linker, and the CRBN ligand Pomalidomide, SJ988497 is utilized in researching acute lymphoblastic leukemia (ALL) [1].
价 格:¥电议型 号:T74994产 地:中国大陆
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T74988DIBA-Cy5;化合物 DIBA-Cy5DIBA-Cy5
DIBA-Cy5, a fluorescent DIBA antagonist, consists of DIBA-alkyne and Cyanine5 fluorophores (Cy5) linked by a polyethylene glycol (PEG) chain. It functions as a fluorescent ligand for probe attachment via click chemistry, exhibiting high binding affinity to type-2 mAChR (M2R) with a dissociation constant (Kd) of 1.80 nM. Notably, DIBA-Cy5 effectively stains M2R receptors in the sinoatrial node of mouse hearts [1].
价 格:¥电议型 号:T74988产 地:中国大陆
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T73361RP101988;化合物 RP101988RP101988
RP101988, the principal active metabolite of Ozanimod, is a potent and selective agonist for sphingosine-1-phosphate receptor 1 (S1PR1), exhibiting half-maximal effective concentrations (EC50s) of 0.19 nM for S1PR1 and 32.8 nM for S1PR5.
价 格:¥电议型 号:T73361产 地:中国大陆
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T72988photoCORM-2;化合物 photoCORM-2photoCORM-2
photoCORM-2 is a single carbon monoxide releasing molecule (CORM). photoCORM-2 exhibits good cellular uptake and real-time monitoring ability of CO uncaging by a color change approach. photoCORM-2 has anti-tumor activity [1] .
价 格:¥电议型 号:T72988产 地:中国大陆
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T71988Moxaverine hydrochloride;化合物 Moxaverine hydrochlorideMoxaverine hydrochloride
Moxaverine hydrochloride is a derivative of papaverine, a phosphodiesterase inhibitor. Moxaverine has been studied in phase III of a clinical trial for the treatment of ocular blood flow in patients with age- related macular degeneration and primary open angle glaucoma.
价 格:¥电议型 号:T71988产 地:中国大陆
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T71886ALN29882;化合物 ALN29882ALN29882
ALN29882 is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage. 18:1 DG has been used as a diacyl-glycerol source in diacylglycerol O-acyltransferase 1 (DGAT1) assay. It has also been used as substrate to assess compounds as potential inhibitors of DGAT-1 in DGAT-1 enzyme assay. It is suitable to use in lipid-protein overlay screen assay with the recombinant p
价 格:¥电议型 号:T71886产 地:中国大陆
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T71670(rel)-BMS-641988;化合物 BMS-641988(rel)-BMS-641988
(rel)-BMS-641988, a relative configuration of the potent nonsteroidal androgen receptor antagonist BMS-641988, holds potential for prostate cancer research.
价 格:¥电议型 号:T71670产 地:中国大陆
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T71634GSK-598809 L-tartrate;化合物 GSK-598809 L-tartrateGSK-598809 L-tartrate
GSK-598809 L-tartrate is an acute D3 antagonist.
价 格:¥电议型 号:T71634产 地:中国大陆