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T78271Anti-Mouse TCR gamma/delta Antibody (UC7-13D5)；化合物 Anti-Mouse TCR gamma/delta Antibody (UC7-13D5)Ant
Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.
价 格：￥电议型 号：T78271产 地：中国大陆
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T77211Sudan I-d5；化合物 Sudan I-d5Sudan I-d5
Sudan I-d5, the deuterated variant of Sudan I, is a diazo-conjugate red dye utilized in oils, solvents, or polishes as an additive. Notably, it hampers the growth of bacterial strains Clostridium perfringens and L. rhamnosus[1].
价 格：￥电议型 号：T77211产 地：中国大陆
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T76283b-Hydroxy-5-cholenoic acid；3B-羟基-D5-胆烯酸3b-Hydroxy-5-cholenoic acid
3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin
价 格：￥电议型 号：T7628产 地：中国大陆
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T7586trifarotene；曲法罗汀CD5789；CD5789|||曲法罗汀
Trifarotene (CD5789) is a potent and selective RARγ agonist with 65-fold and 16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM).
价 格：￥电议型 号：T7586产 地：中国大陆
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T73507NS1219；化合物 NS1219(R)-SPD502；(R)-SPD502
NS1219 ((R)-SPD502), an isomer of NS1209, functions as a selective antagonist for AMPA receptors, exhibiting neuroprotective properties. This compound is utilized in research related to stroke, neuropathic pain, and epilepsy.
价 格：￥电议型 号：T73507产 地：中国大陆
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T73107RAD51-IN-4；化合物 RAD51-IN-4RAD51-IN-4
RAD51-IN-4 is a potent RAD51 inhibitor, targeting a eukaryote gene critical for studies on conditions associated with mitochondrial defects.
价 格：￥电议型 号：T73107产 地：中国大陆
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T71984Enrofloxacin-d5；化合物 Enrofloxacin-d5Enrofloxacin-d5
Enrofloxacin-d5 is intended for use as an internal standard for the quantification of enrofloxacin by GC- or LC-MS. Enrofloxacin is a fluoroquinolone antibiotic. It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 ?g/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 ?g/ml). Enrofloxacin inhibits bacterial DNA gyrase. In vivo, enrofloxacin (10 mg/kg) increases survival in a mouse model
价 格：￥电议型 号：T71984产 地：中国大陆
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T71893Clobetasol Propionate-d5；化合物 Clobetasol Propionate-d5Clobetasol Propionate-d5
Clobetasol propionate-d5 is intended for use as an internal standard for the quantification of clobetasol propionate by GC- or LC-MS. Clobetasol propionate is a corticosteroid. It binds to glucocorticoid receptors in a cell-free assay and inhibits proliferation of primary human skin fibroblasts when used at a concentration of 5 ?g/ml. Topical administration of clobetasol propionate reduces croton oil-induced ear edema in mice. Formulations containing clobetasol propionate have been used in the t
价 格：￥电议型 号：T71893产 地：中国大陆
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T71442CD564；化合物 CD564CD564
CD564 is a novel selective inhibitor of RARβ/γ.
价 格：￥电议型 号：T71442产 地：中国大陆
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T71436D561-0775；化合物 D561-0775D561-0775
D561-0775 is a direct AMPK agonist, showing potential anti-cancer activity via inducing apoptosis, cell cycle arrest, suppressing glycolysis and cholesterol synthesis after activation of AMPK in gefitinib-resistant H1975 cells.
价 格：￥电议型 号：T71436产 地：中国大陆
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T71423AZD5213；化合物 AZD-5213AZD5213
AZD5213 is a selective, competitive antagonist of the human H3 receptor, exhibiting a pK i of 9.3 against hH3R. It is utilized in the research of sleep and cognitive regulation.
价 格：￥电议型 号：T71423产 地：中国大陆
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T71302Norfluoxetine-d5 HCl；化合物 Norfluoxetine-d5 HClNorfluoxetine-d5 HCl
Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa
价 格：￥电议型 号：T71302产 地：中国大陆
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T71143Ambroxol-d5；化合物 Ambroxol-d5Ambroxol-d5
Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous part
价 格：￥电议型 号：T71143产 地：中国大陆
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T71141Fenspiride-d5；化合物 Fenspiride-d5Fenspiride-d5
Fenspiride-d5 is intended for use as an internal standard for the quantification of fenspiride by GC- or LC-MS. Fenspiride is an antagonist of histamine H1 receptors and a non-steroidal anti-inflammatory drug (NSAID). It inhibits histamine-induced contraction of isolated guinea pig trachea but not histamine-induced inotropy of isolated guinea pig heart. It also inhibits phosphodiesterase 4 (PDE4), PDE5, and PDE3 (IC50s = 69, ~158, and 363 ?M, respectively, in isolated human bronchi derived from
价 格：￥电议型 号：T71141产 地：中国大陆
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T71117AZD5248；化合物 AZD5248AZD5248
AZD-5248 is a potent, selective, first generation, oral inhibitor of dipeptidyl peptidase 1 (DPP1).
价 格：￥电议型 号：T71117产 地：中国大陆
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T71065Quinapril-d5；化合物 Quinapril-d5Quinapril-d5
Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations con
价 格：￥电议型 号：T71065产 地：中国大陆
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T70883Moexipril-d5；化合物 Moexipril-d5Moexipril-d5
Moexipril-d5 intended for use as an internal standard for the quantification of moexipril by GC- or LC-MS. Moexipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor moexiprilat. It is converted to moexiprilat in vivo by side chain ester hydrolysis. Moexipril inhibits ACE in a cell-free assay (IC50 = 2.7 ?M for the rabbit enzyme). It also inhibits phosphodiesterase 4 (IC50s = 38, 160, and 230 ?M for PDE4B2, PDE4A5 and PDE4D5, respectively). Moexipril (0.1-30 mg/kg per day)
价 格：￥电议型 号：T70883产 地：中国大陆
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T70313Indoxyl Sulfate-d5 potassium salt；化合物 Indoxyl Sulfate-d5 potassium saltIndoxyl Sulfate-d5 potassium
Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay).
价 格：￥电议型 号：T70313产 地：中国大陆
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T7005LUlixertinib hydrochloride化合物 T7005LUlixertinib HCl|||BVD-523|||VRT752271|||BVD 523|||BVD523|||VRT 75
Ulixertinib is an inhibitor of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival.
价 格：￥电议型 号：T7005L产 地：中国大陆
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T70040BRD5814；化合物 BRD5814BRD5814
BRD5814 is a highly brain penetrant β-arrestin biased D2R antagonist.
价 格：￥电议型 号：T70040产 地：中国大陆
