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T70035Tasimelteon-d5；化合物 Tasimelteon-d5Tasimelteon-d5
Tasimelteon-d5 is intended for use as an internal standard for the quantification of tasimelteon by GC- or LC-MS. Tasimelteon is a melatonin (MT) receptor agonist. It selectively binds MT1 and MT2 receptors over a panel of 160 additional receptors and enzymes at 10 ?M. Tasimelteon inhibits forskolin-induced cAMP accumulation with EC50 values of 0.79 and 1 nM in NIH3T3 cells expressing the MT1 or MT2 receptor, respectively. Formulations containing tasimelteon have been used in the treatment of no
价 格：￥电议型 号：T70035产 地：中国大陆
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T69970AZD5718；化合物 AZD5718AZD5718
AZD5718 is a potent and selective FLAP inhibitor (IC50 = 2.0 nM) for Treatment of Coronary Artery Disease. AZD5718 demonstrated a dose dependent and greater than 90% suppression of leukotriene production over 24 h. Preclinical toxicology studies in rat and dog did not show any serious adverse events of clinical significance. Currently, AZD5718 is evaluated in a phase 2a study for treatment of coronary artery disease.
价 格：￥电议型 号：T69970产 地：中国大陆
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T69966Roxadustat-d5；化合物 Roxadustat-d5Roxadustat-d5
Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 ?M for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 ?M for all). Roxadustat (10-200 ?M) stabilizes HIF-1α and
价 格：￥电议型 号：T69966产 地：中国大陆
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T68718103D5R；化合物 103D5R103D5R
103D5R is a novel selective inhibitor of hif-1α, markedly decreasing hif-1α protein levels induced by hypoxia or cobaltous ions in a dose- and time-dependent manner
价 格：￥电议型 号：T68718产 地：中国大陆
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T67921Retinoic acid-d5；视黄酸d5all-trans-Retinoic acid-d5|||Isotretinoin-d5|||Vitamin A acid-d5|||Accutane-d5
Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a metabolite of vitamin A, plays an important role in cell growth, differentiation and organ development. Retinoic acid acts by activating retinoic acid receptor alpha as an inhibitor of the transcription factor Nrf2.
价 格：￥电议型 号：T67921产 地：中国大陆
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T67901SRD5A1-IN-1；化合物SRD5A1-IN-1SRD5A1-IN-1
SRD5A1-IN-1 is an inhibitor of steroid 5α-reductase type 1 (SRD5A1, IC50 = 1.44 ?M). SRD5A1-IN-1 lowers the production of dihydrotestosterone and shows a significant decrease in the SRD5A1 protein expression.
价 格：￥电议型 号：T67901产 地：中国大陆
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T676745,6-Dichloronicotinic acid；化合物 5,6-Dichloronicotinic acid5,6-Dichloronicotinic acid
5,6-Dichloronicotinic acid is a useful organic compound for research related to life sciences. The catalog number is T67674 and the CAS number is 41667-95-2.
价 格：￥电议型 号：T67674产 地：中国大陆
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T675045-Nitronicotinic acid；化合物 5-Nitronicotinic acid5-Nitronicotinic acid
5-Nitronicotinic acid is a useful organic compound for research related to life sciences. The catalog number is T67504 and the CAS number is 2047-49-6.
价 格：￥电议型 号：T67504产 地：中国大陆
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T674995-Bromonicotinic acid；化合物 5-Bromonicotinic acid5-Bromonicotinic acid
5-Bromonicotinic acid is a useful organic compound for research related to life sciences. The catalog number is T67499 and the CAS number is 20826-04-4.
价 格：￥电议型 号：T67499产 地：中国大陆
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T674975-Aminonicotinic acid；化合物 5-Aminonicotinic acid5-Aminonicotinic acid
5-Aminonicotinic acid is a useful organic compound for research related to life sciences. The catalog number is T67497 and the CAS number is 24242-19-1.
价 格：￥电议型 号：T67497产 地：中国大陆
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T673725-Chloro-1H-indole-3-carboxylic acid；化合物 5-Chloro-1H-indole-3-carboxylic acid5-Chloro-1H-indole-3-ca
5-Chloro-1H-indole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67372 and the CAS number is 10406-05-0.
价 格：￥电议型 号：T67372产 地：中国大陆
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T672835-Methylsalicylic acid；化合物 5-Methylsalicylic acid5-Methylsalicylic acid
5-Methylsalicylic acid is a useful organic compound for research related to life sciences. The catalog number is T67283 and the CAS number is 89-56-5.
价 格：￥电议型 号：T67283产 地：中国大陆
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T664965-Methylisoxazole-4-carboxylic acid；化合物 5-Methylisoxazole-4-carboxylic acid5-Methylisoxazole-4-carbo
5-Methylisoxazole-4-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66496 and the CAS number is 42831-50-5.
价 格：￥电议型 号：T66496产 地：中国大陆
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T664475-Chlorothiophene-2-carboxylic acid；化合物 5-Chlorothiophene-2-carboxylic acid5-Chlorothiophene-2-carbo
5-Chlorothiophene-2-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66447 and the CAS number is 24065-33-6.
价 格：￥电议型 号：T66447产 地：中国大陆
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T663125-Aminoisophthalic acid；化合物 5-Aminoisophthalic acid5-Aminoisophthalic acid
5-Aminoisophthalic acid is a useful organic compound for research related to life sciences. The catalog number is T66312 and the CAS number is 99-31-0.
价 格：￥电议型 号：T66312产 地：中国大陆
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T662815-Fluoro-2-methyl-3-nitrobenzoic acid；化合物 5-Fluoro-2-methyl-3-nitrobenzoic acid5-Fluoro-2-methyl-3-n
5-Fluoro-2-methyl-3-nitrobenzoic acid is a useful organic compound for research related to life sciences. The catalog number is T66281 and the CAS number is 850462-64-5.
价 格：￥电议型 号：T66281产 地：中国大陆
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T656895-Amino-3-(4-chlorophenyl)-5-oxopentanoic acid；化合物 5-Amino-3-(4-chlorophenyl)-5-oxopentanoic acid5-A
5-Amino-3-(4-chlorophenyl)-5-oxopentanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65689 and the CAS number is 1141-23-7.
价 格：￥电议型 号：T65689产 地：中国大陆
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T653065-Methoxy-2-methyl-3-indoleacetic acid；化合物 5-Methoxy-2-methyl-3-indoleacetic acid5-Methoxy-2-methyl-
5-Methoxy-2-methyl-3-indoleacetic acid is a useful organic compound for research related to life sciences. The catalog number is T65306 and the CAS number is 2882-15-7.
价 格：￥电议型 号：T65306产 地：中国大陆
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T651705-(4-Fluorophenyl)-5-oxopentanoic acid；化合物 5-(4-Fluorophenyl)-5-oxopentanoic acid5-(4-Fluorophenyl)-
5-(4-Fluorophenyl)-5-oxopentanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65170 and the CAS number is 149437-76-3.
价 格：￥电议型 号：T65170产 地：中国大陆
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T65001Benzoicacid-d5；化合物 Benzoicacid-d5Benzoicacid-d5
Benzoicacid-d5 is a useful organic compound for research related to life sciences. The catalog number is T65001 and the CAS number is 1079-02-3.
价 格：￥电议型 号：T65001产 地：中国大陆
