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产品数:86101
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T6548IrsogladinePhosphodiesterase (PDE),mAChR,inhibit,Irsogladine,Muscarinic acetylcholine receptor,Inhib
Irsogladine is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.
价 格:¥电议型 号:T6548产 地:中国大陆
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T9521CHR-6494 TFACHR-6494,inhibit,apoptosis,Haspin Kinase,NRAS mutant melanoma cells,CHR 6494,mitotic cat
CHR-6494 TFA is a potent haspin inhibitor, with an?IC50?of 2 nM. It inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the?apoptosis?of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be used in the research of cancer
价 格:¥电议型 号:T9521产 地:中国大陆
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T6312R547Glycogen synthase kinase 3,kinase,multiple,tumor,cyclin-dependent,R547,Apoptosis,Cyclin dependen
R547 is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.
价 格:¥电议型 号:T6312产 地:中国大陆
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T9172Simufilam dihydrochlorideInhibitor,PTI-125,Simufilam,inhibit,PTI 125,PTI125,Simufilam dihydrochlorid
Simufilam dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer´s disease. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
价 格:¥电议型 号:T9172产 地:中国大陆
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TN1373α-Humuleneα Humulene,Inhibitor,α-Humulene,Humulene,NOS,αHumulene,inhibit,COX,Nitric oxide synthases,
α-Humulene is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production and COX-2 and iNOS expression.
价 格:¥电议型 号:TN1373产 地:中国大陆
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T7414ARS-853ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,c
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
价 格:¥电议型 号:T7414产 地:中国大陆
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T7555Piperidolate hydrochlorideInhibitor,Piperidolate,inhibit,Muscarinic acetylcholine receptor,Piperidol
Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs).
价 格:¥电议型 号:T7555产 地:中国大陆
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T7730AminopterinAminopterin,tetrahydrofolic,inhibit,anticancer,immunosuppressive,acid,Antifolate,leukocyt
Aminopterin is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase
价 格:¥电议型 号:T7730产 地:中国大陆
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T8196ArborineMuscarinic acetylcholine receptor,inhibit,Inhibitor,mAChR,Arborine
Arborine is a larval growth inhibitor from glycoslnis pentaphylla.
价 格:¥电议型 号:T8196产 地:中国大陆
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T9852MUN36378MUN36378
MUN36378 is a FTO inhibitor for treatment of leukemia.
价 格:¥电议型 号:T9852产 地:中国大陆
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TN10841,3,5,8-TetrahydroxyxanthoneInhibitor,colitis,anti-inflammatory,muscle,inhibit,1,3,5,8-Tetrahydroxyx
Desmethylbellidifolin is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity. Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method; it also exhibits at the dose of 200 ug/disk a significant inhibition of the growth of Staphylococcus aureus.
价 格:¥电议型 号:TN1084产 地:中国大陆
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T9982PU23MRP4,PU23,resistance,PU-23,Inhibitor,inhibit,protein,PU 23,6-Mercaptopurine,multidrug
PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).
价 格:¥电议型 号:T9982产 地:中国大陆
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T16040Mepazinediffuse,B cell,inhibit,large,mucosa associated lymphoid tissue lymphoma translocation gene 1
Mepazine is a potent and selective inhibitor of MALT1. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 μM and 0.42 μM. Mepazine enhances apoptosis and affects the cell viability.
价 格:¥电议型 号:T16040产 地:中国大陆
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T8692(Rac)-Benpyrineautoimmune,Inhibitor,anti-inflammatory,(Rac) Benpyrine,(Rac)-Benpyrine,Tumor Necrosis
(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.
价 格:¥电议型 号:T8692产 地:中国大陆
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T9003CVT-11127Inhibitor,apoposis,GS 456332,S-phase,monounsaturated fatty acids (MUFA),Stearoyl-CoA Desatu
CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
价 格:¥电议型 号:T9003产 地:中国大陆
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T7624DAPTAHIV,DAPTA,CC chemokine receptor,Human immunodeficiency virus,inhibit,CCR,Inhibitor
DAPTA(TFA) is an inhibitor of CCR5, shows potent anti-HIV activities.
价 格:¥电议型 号:T7624产 地:中国大陆
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T7329C-178MITA,inhibit,Inhibitor,STING,MPYS,C178,ERIS,C-178,C 178,Stimulator of Interferon Genes,TMEM173
C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.
价 格:¥电议型 号:T7329产 地:中国大陆
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T7079BatefenterolGSK-961081,mAChR,inhibit,TD 5959,Muscarinic acetylcholine receptor,GSK 961081,Adrenergic
Batefenterol (GSK961081, TD-5959) is a muscarinic receptor antagonist and β2-adrenoceptor agonist. It displays high affinity for hM2, hM3 muscarinic and hβ2-adrenoceptor (Ki:1.4/1.3/3.7 nM).
价 格:¥电议型 号:T7079产 地:中国大陆
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T9906IpilimumabBMS734016,MDX010,Ipilimumab,inhibit,BMS-734016,BMS 734016,Inhibitor,MDX 010,MDX-010
Ipilimumab anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.
价 格:¥电议型 号:T9906产 地:中国大陆
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T9689M4205factor,M-4205,receptor,M4205,cell,CD117,growth,inhibit,mast/stem,mutations,SCFR,c-Kit,M 4205,In
M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.
价 格:¥电议型 号:T9689产 地:中国大陆