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T67873USP8-IN-3;化合物USP8-IN-3USP8-IN-3
USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 μM against USP8D. USP8-IN-3 inhibited the proliferation of GH3 and H1957 cells with GI50 values of 37.03 μM and 6.01 μM, respectively. USP8-IN-3 is a potential compound for the treatment of cancer and viral infections.
价 格:¥电议型 号:T67873产 地:中国大陆
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T63625USP1-IN-3;化合物 USP1-IN-3USP1-IN-3
USP1-IN-3 is a selective inhibitor of USPI that inhibits USPI-UAFI (IC50<30 nM). USP1-IN-3 can be used to study cancer.
价 格:¥电议型 号:T63625产 地:中国大陆
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T63518USP1-IN-2;USP1 抑制剂2USP1-IN-2
USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.
价 格:¥电议型 号:T63518产 地:中国大陆
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T61575USP15-IN-1;化合物USP15-IN-1USP15-IN-1
USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM). USP15-IN-1 showed high antiproliferative activity against non-small cell lung cancer and leukemia cells. USP15 is an interacting protein of cGAS, and USP15 can promote cGAS to recognize DNA and activate downstream signaling pathways.
价 格:¥电议型 号:T61575产 地:中国大陆
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T60146USP8-IN-1;USP8抑制剂USP8-IN-1
USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI 50 of 82.04 μM [1].
价 格:¥电议型 号:T60146产 地:中国大陆
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T60130USP5-IN-1;化合物USP5-IN-1USP5-IN-1
USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor, which binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate [1].
价 格:¥电议型 号:T60130产 地:中国大陆
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T60039KSQ-4279;化合物KSQ-4279USP1-IN-1;USP1-IN-1
KSQ-4279 (USP1-IN-1) is an inhibitor of USP1 and PARP.KSQ-4279 has anticancer activity and is used in the study of non-small cell lung cancer, osteosarcoma, ovarian, breast, glioblastoma, bladder, uterine and pancreatic cancers.
价 格:¥电议型 号:T60039产 地:中国大陆
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T4338USP7/USP47 inhibitor;化合物USP7/USP47 inhibitorUSP7/47 inhibitor-1;USP7/47 inhibitor-1
USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM, respectively.
价 格:¥电议型 号:T4338产 地:中国大陆
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T36991Monascuspiloin;MonascuspiloinMonascuspiloin
Monascuspiloin is a fungal metabolite that has been found inM. pilosusM93-fermented rice.1It induces endoplasmic reticulum stress and autophagy in PC3 prostate cancer cells. Monascuspiloin (15-45 μM) decreases viability of PC3 cells and has an additive effect on the reduction in viability of PC3 cells induced by irradiation when used at a concentration of 25 μM. It induces intratumor apoptosis and autophagy and reduces tumor growth in a PC3 mouse xenograft model when administered at doses of 40
价 格:¥电议型 号:T36991产 地:中国大陆
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T36682USP30 inhibitor 18;化合物USP30 inhibitor 18USP30 inhibitor 18
USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 μM). USP30 inhibitor 18 is able to accelerate mitophagy and increase protein ubiquitination.
价 格:¥电议型 号:T36682产 地:中国大陆
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T35594Cuspin-1Cuspin-1Cuspin 1|||Cuspin1
The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA). Cuspin-1 is a small molecule upregulator of SMN that has been shown in vitro to increase levels of SMN in SMA patient fibroblasts by 50% at 18 μM. Its mechanism of action is thought to involve increased phosphorylation of ERK to initiate Ras-Ra
价 格:¥电议型 号:T35594产 地:中国大陆
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T32020Gusperimus;化合物 T32020Deoxyspergualin|||15-Deoxyspergualin;Deoxyspergualin|||15-Deoxyspergualin
Gusperimus was synthesized by chemical modification of spergualin and in combination with cyclosporine A to prevent diabetes in susceptible NOD mice.
价 格:¥电议型 号:T32020产 地:中国大陆
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T31113Cuspidoside;化合物 T31113Lokundjosid|||Locundioside|||Bipindogenin-L-rhamnosid;Lokundjosid|||Locundiosi
Cuspidoside is a cardiac glycoside.
价 格:¥电议型 号:T31113产 地:中国大陆
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T29998Amlodipine besilate impurity F;化合物 T29998Amlodipine Dimethyl Ester|||Amlodipine USP Related Compound
Amlodipine besilate impurity F, also known as Amlodipine Dimethyl Ester, is a biochemical.
价 格:¥电议型 号:T29998产 地:中国大陆
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T27635Isoxepac;伊索克酸antipyretic|||伊索克酸|||inhibit|||HP 549|||HP-549|||Isoxepac|||HP549|||Olopatadine USP Rel
Isoxepac (Olopatadine USP Related Compound C) is a non-steroidal anti-antiphlogistic agent and analgesic.
价 格:¥电议型 号:T27635产 地:中国大陆
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T25432Fluspiperone;化合物 T25432NSC 354855|||NSC354855|||NSC-354855|||R-28930|||R 28930;NSC 354855|||NSC35485
Fluspiperone is an antipsychotic agent.
价 格:¥电议型 号:T25432产 地:中国大陆
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T2132Buspirone hydrochloride;盐酸丁螺环酮Buspirone HCl|||Narol|||Buspar;Buspirone HCl|||盐酸丁螺环酮|||Narol|||Buspar
Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).
价 格:¥电议型 号:T2132产 地:中国大陆
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T21011Buspirone丁螺环酮Buspirone free base|||Ansial|||丁螺环酮
Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.
价 格:¥电议型 号:T21011产 地:中国大陆
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T1698Carvedilol EP IMpurity E;卡维地洛杂质Carvedilol USP E|||Carvedilol Impurity E;Carvedilol USP E|||Carvedilo
Carvedilol EP IMpurity E (Carvedilol USP E) is used as a pharmaceutical intermediate.
价 格:¥电议型 号:T1698产 地:中国大陆
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T15301Fluspirilene;氟司必林Redeptin|||R 6218;Redeptin|||R 6218
Fluspirilene (R 6218) is a non-competitive L-type calcium channel antagonist (IC50: 0.03 μM).Fluspirilene is a long-acting antipsychotic compound used in the treatment of schizophrenia.
价 格:¥电议型 号:T15301产 地:中国大陆