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产品数：86101
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TN6512TectolHL60,Ftase,Inhibitor,cell,anti-malarial,Parasite,cytotoxic,inhibit,leukemia,drug-resistant,Tec
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area.
价 格：￥电议型 号：TN6512产 地：中国大陆
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T8353Pamoic acidPamoic acid,GPR35,neuroprotective,Extracellular signal regulated kinases,Inhibitor,inhibi
Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
价 格：￥电议型 号：T8353产 地：中国大陆
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T9689M4205factor,M-4205,receptor,M4205,cell,CD117,growth,inhibit,mast/stem,mutations,SCFR,c-Kit,M 4205,In
M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.
价 格：￥电议型 号：T9689产 地：中国大陆
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T9195SHR0302Th17,SHR-0302,B-cell,Inhibitor,inhibit,arthritis,collagen,migration,hepatic,SHR0302,JAK1,phos
SHR0302 is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).
价 格：￥电议型 号：T9195产 地：中国大陆
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T9370dCBP-1Inhibitor,p300,multiple,CRBN,myeloma,cell,degrader,PROTACs,MYC,CBP,inhibit,dCBP 1,dCBP1,hetero
dCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing.
价 格：￥电议型 号：T9370产 地：中国大陆
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T9135EpirosmanolEpirosmanol,inhibit,melanoma cells,scavenging activity,melanin,Inhibitor,antioxidant,dite
Epirosmanol belongs to the class of organic compounds known as diterpene lactones. These are diterpenoids containing a lactone moiety. Epirosmanol is an extremely weak basic (essentially neutral) compound (based on its pKa).
价 格：￥电议型 号：T9135产 地：中国大陆
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TP1328TB500cell differentiation,keratinocyte migration,TB500,collagen deposition,TB 500,TB-500,thymosin β
TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.
价 格：￥电议型 号：TP1328产 地：中国大陆
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T8546BD750Immunosuppressant,JAK,BD750,cell,Janus kinase,BD-750,inhibit,STAT,Inhibitor,BD 750
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in mouse and human T cells, respectively)
价 格：￥电议型 号：T8546产 地：中国大陆
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T9564IRE1α kinase-IN-1endoribonuclease,Inositol requiring enzyme 1,cells,IRE1,oligomerization,IRE-1α kina
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosphorylation, and also inhibits IRE1α RNase activity (IC50=80 nM)
价 格：￥电议型 号：T9564产 地：中国大陆
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T11492GSK2983559 free acidinhibit,THP-1 cell,RIP kinase,GSK 2983559,GSK2983559 free acid,Inhibitor,GSK-298
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples an
价 格：￥电议型 号：T11492产 地：中国大陆
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T8762SW106065cell,SW 106065,cdk4,Inhibitor,MPNST,cycle,ATP,anticancer,cdk6,cyclin,SW106065,Apoptosis,inhi
SW-106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). It inhibits ATP consumption of sMPNST and other models of MPNST with an EC50 of 1 μM. SW106065 can be used for MPNST research
价 格：￥电议型 号：T8762产 地：中国大陆
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T21588OlomoucineOlomoucine,Inhibitor,cyclindependent kinases,cdc2,purines,cell cycle,non-small cell lung c
Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 ?M, respectively. Olomoucine regulates cell cycle and exhibits anti-melanin tumor activities.
价 格：￥电议型 号：T21588产 地：中国大陆
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T7799BMP signaling agonist sb4Inhibitor,SMAD,bmp,cell,inhibit,BMP signaling agonist sb4,BRE-luc,BMP signa
SB 4 is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
价 格：￥电议型 号：T7799产 地：中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格：￥电议型 号：T9303产 地：中国大陆
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TQ0126Mirodenafil dihydrochlorideSK3530,Inhibitor,Wnt,Beta catenin,Mirodenafil,SK-3530,MRC-5 cells,Miroden
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
价 格：￥电议型 号：TQ0126产 地：中国大陆
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T40101(±)-1,2-Dioleinmuscle,Protein kinase C,Inhibitor,PKC α,skeletal,myoblasts,inhibit,PKC,cell,(±) 1,2 D
(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.
价 格：￥电议型 号：T40101产 地：中国大陆
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TN2346MogrolERK,inhibit,Extracellular signal regulated kinases,STAT,Mogrol,Inhibitor
Mogrol is a biometabolite of mogrosides. Mogrol acts via inhibition of the ERK1/2 and STAT3 pathways, or reducing CREB activation and activating AMPK signaling.
价 格：￥电议型 号：TN2346产 地：中国大陆
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TN1839Kumatakeninovarian,Inhibitor,cell,Apoptosis,inhibit,Kumatakenin,cancer
Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.
价 格：￥电议型 号：TN1839产 地：中国大陆
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T6S0619Pachymic acidPachymic acid,PKB,Protein kinase B,inhibit,Akt,ERK,Extracellular signal regulated kinas
Pachymic acid is a natural product, and inhibits Akt and ERK signaling pathways.
价 格：￥电议型 号：T6S0619产 地：中国大陆
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T8545FEN1-IN-4flap,colorectal,Inhibitor,endonuclease,FEN1IN4,cells,colon,cancer,inhibit,FEN-1-IN-4,gliobl
FEN1-IN-4 is an inhibitor of human flap endonuclease-1 (hFEN1)
价 格：￥电议型 号：T8545产 地：中国大陆
