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产品数:86101
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T8188PodophyllotoxoneInhibitor,DU145,inhibit,Podophyllotoxone,cancer,Microtubule/Tubulin,PC3,cells,prosta
Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro.
价 格:¥电议型 号:T8188产 地:中国大陆
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T8959OS-3-106Inhibitor,inhibit,Dopamine Receptor,HEK 293 cells,self-administration,arylamide phenylpipera
OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay.
价 格:¥电议型 号:T8959产 地:中国大陆
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T6S1740Nardosinonecells,Nardosinone,Neurite,substances,PC12D,outgrowth-promoting,neuritogenic,inhibit,MAPK,
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and stau
价 格:¥电议型 号:T6S1740产 地:中国大陆
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T40187GNF2133β-cell,RIP-DTA mice,Inhibitor,insulin secretion,GNF2133,inhibit,Dual specificity tyrosine reg
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.
价 格:¥电议型 号:T40187产 地:中国大陆
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T6S0655CorynoxeineExtracellular signal regulated kinases,ERK,Corynoxeine,Inhibitor,inhibit
1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.
价 格:¥电议型 号:T6S0655产 地:中国大陆
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T8239Cromoglicic acidallergic rhinitis,Cromolyn,bronchial asthma,Cromoglicic acid,cell stabilizer,inhibit
Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.
价 格:¥电议型 号:T8239产 地:中国大陆
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T7155JH-II-127HEK293,JHII127,3T3 cells,Inhibitor,LRRK2-G2019S,Ser935,Leucine-rich repeat kinase 2,LRRK2,p
JH-II-127 is an orally inhibitor of leucine-rich repeat kinase 2 (LRRK2). It inhibits WT LRRK2, G2019S LRRK2 and A2016T LRRK2 (IC50s = 6.6, 2.2, and 47.7 nM, respectively),
价 格:¥电议型 号:T7155产 地:中国大陆
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T6993Tauroursodeoxycholate sodiummolecules,UR-906,Caspase,UR 906,Extracellular signal regulated kinases,r
Tauroursodeoxycholate Sodium is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
价 格:¥电议型 号:T6993产 地:中国大陆
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T6812Cyclo(-RGDfK)Cyclo(-RGDfK),inhibit,Microvasculature,cancer,Integrin,tumoral cell,αvβ3 integrin,Cyclo
Cyclo (-RGDfK) is an effective and specific αvβ3 integrin inhibitor.
价 格:¥电议型 号:T6812产 地:中国大陆
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T60076Oritinibpharmacodynamics,non-small cell lung cancer,EGFR-T790M,EGFR TKI,SH1028,Irreversible,mutant-s
Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can be used in studies about the treatment of non-small cell lung cancer.
价 格:¥电议型 号:T60076产 地:中国大陆
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T8531m-3M3FBScalcium,superoxide,cells,THP-1,phosphate,m 3M3FBS,m-3M3FBS,Apoptosis,Inhibitor,m3M3FBS,Phosp
m-3M3FBS is a phospholipase C (PLC) activator.
价 格:¥电议型 号:T8531产 地:中国大陆
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T8697ZAP-180013Inhibitor,autoimmune,ZAP-70,tyrosine,T-cell,ZAP 180013,ZAP180013,Tyrosinase,ZAP-180013,ant
ZAP-180013 is an inhibitor of zeta-chain-associated protein kinase 70 (ZAP70,IC50 : 1.8 μM).
价 格:¥电议型 号:T8697产 地:中国大陆
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T6941PI-1840cell proliferation,Proteasome,Caspase,proteasome substrates,poly ADP ribose polymerase,inhibi
PI-1840( IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).
价 格:¥电议型 号:T6941产 地:中国大陆
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T8313HCH6-1inhibit,inflammatory,FPR1,HCH6-1,cell infiltration,HCH6 1,antagonist,pulmonary,acute lung inju
HCH6-1 is a competitive Formyl peptide receptor 1 (FPR1) antagonist.
价 格:¥电议型 号:T8313产 地:中国大陆
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TQ0005KO-947Inhibitor,ERK,KO-947,inhibit,KO 947,Extracellular signal regulated kinases,KO947
KO-947 is a potent and specific inhibitor of ERK1/2 kinases.
价 格:¥电议型 号:TQ0005产 地:中国大陆
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T8851I3MT-3EA.hy926 cells,Hippo (MST),inhibit,I3MT-3,3MST,HEK293,I3MT3,cell-membrane,COS-7,I-3MT-3,I3MT 3
I3MT-3 (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST.
价 格:¥电议型 号:T8851产 地:中国大陆
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T9831MKC-1inhibit,mTOR,Apoptosis,Protein kinase B,PKB,MKC 1,renal cell cancer,Caki-1,Mammalian target of
MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in
价 格:¥电议型 号:T9831产 地:中国大陆
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T8242Sabineneskeletal muscle atrophy,L6 cells,bicyclic monoterpene,Makino essential oil,Chrysanthemum bor
Sabinene is a natural product that has antifungal and anti-inflammatory properties
价 格:¥电议型 号:T8242产 地:中国大陆
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T9988WAY-328173osteoblasts,β-catenin,WAY328173,Beta catenin,cells,differentiation,transmission,inhibit,In
WAY-328173 is a Wnt/beta-catenin agonist.
价 格:¥电议型 号:T9988产 地:中国大陆
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T12871Talmapimodcytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation
Talmapimod is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
价 格:¥电议型 号:T12871产 地:中国大陆