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T37499Estriol 3-glucuronide;Estriol 3-glucuronideEstriol 3-glucuronide
Estriol-3-glucuronide, a natural compound found in urine, is also present in amniotic fluid during normal pregnancy [1][2].
价 格:¥电议型 号:T37499产 地:中国大陆
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T374841-Salicylate Glucuronide;1-Salicylate Glucuronide1-Salicylate Glucuronide
1-Salicylate glucuronide is a metabolite of salicylic acid and aspirin .1It is formed from salicylic acid primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A9 but also by a variety of other UGT isoforms and from aspirinviasalicylic acid as an intermediate.
价 格:¥电议型 号:T37484产 地:中国大陆
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T37378Propofol β-D-Glucuronide;Propofol β-D-GlucuronidePropofol β-D-Glucuronide
Propofol β-D-glucuronide is a metabolite of propofol sulfate , a short-acting anesthetic agent. [1] [2] The metabolite is generated through the glucuronidation of propofol by uridine diphosphate glucuronosyltransferases. Propofol metabolism appears to occur more rapidly in women than men. [1]
价 格:¥电议型 号:T37378产 地:中国大陆
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T373647-hydroxy Coumarin Glucuronide (sodium salt);7-hydroxy Coumarin Glucuronide (sodium salt)7-hydroxy C
7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism.
价 格:¥电议型 号:T37364产 地:中国大陆
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T37251Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide;Celecoxib Carboxylic Acid Acyl-β-D-GlucuronideCelecox
Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib . Celecoxib is an anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-2 (COX-2; IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). Celecoxib carboxylic acid acyl-β-D-glucuronide is a minor metabolite, accounting for 2% of the administered dose in human urine and rat bile.
价 格:¥电议型 号:T37251产 地:中国大陆
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T37117Etodolac Acyl Glucuronide;Etodolac Acyl GlucuronideEtodolac Acyl Glucuronide
Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac .1It is formedviaglucuronidation of etodolac by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A9, UGT1A10, and UGT2B7.
价 格:¥电议型 号:T37117产 地:中国大陆
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T37005Estriol 3-β-D-Glucuronide (sodium salt);Estriol 3-β-D-Glucuronide (sodium salt)Estriol 3-β-D-Glucuro
Estriol 3-β-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membranes with Kd values of 85 and 164 μM, respectively. It competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide and is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc).
价 格:¥电议型 号:T37005产 地:中国大陆
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T37004Estradiol 3-sulfate 17β-Glucuronide (potassium salt);Estradiol 3-sulfate 17β-Glucuronide (potassium
Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol , and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma. Sulfated estrogens, including estradiol 3-sulfate, can be converted back to the parent compound by sulfatases. Estradiol 3-sulfate 17β-glucuronide is a metabolite of estradiol 3-sulfate that has been modified by a UDP-glucuronosyltransferase. Glucuronidation of estrogens enhances their utilization by anion transporters, most com
价 格:¥电议型 号:T37004产 地:中国大陆
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T36917Ethynyl Estradiol 3-β-D-Glucuronide (hydrate);Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)Ethynyl E
Ethynyl estradiol 3-β-D-glucuronide is a metabolite of ethynyl estradiol that can be detected in urine.1,2It is used as a marker of estrogen contamination in fresh and saltwater.2
价 格:¥电议型 号:T36917产 地:中国大陆
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T36916Estrone-3-Glucuronide (sodium salt hydrate);Estrone-3-Glucuronide (sodium salt hydrate)Estrone-3-Glu
Estrone-3-Glucuronide is a metabolite of the primary premenopausal estrogen 17β-estradiol .1,2Urinary levels of estrone-3-Glucuronide peak approximately 36 hours prior to ovulation and have been used as a marker of fertility in women.
价 格:¥电议型 号:T36916产 地:中国大陆
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T36826Acetaminophen Glucuronide (sodium salt);Acetaminophen Glucuronide (sodium salt)Acetaminophen Glucuro
Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen . It is formed via glucuronidation of acetaminophen by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A6, UGT1A9, UGT1A1, and UGT2B15.
价 格:¥电议型 号:T36826产 地:中国大陆
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T36807Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate);Estradiol 17-(β-D-Glucuronide) (sodium salt hyd
Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2
价 格:¥电议型 号:T36807产 地:中国大陆
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T36794Dolutegravir O-β-D-Glucuronide;Dolutegravir O-β-D-GlucuronideDolutegravir O-β-D-Glucuronide
Dolutegravir O-β-D-glucuronide is a metabolite of the HIV integrase inhibitor dolutegravir .1It is formed from dolutegravir primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1in vivobut is also metabolized by UGT1A9 in human liver and kidney microsomes and UGT1A3 in human intestinal microsomes.2,1
价 格:¥电议型 号:T36794产 地:中国大陆
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T36128Tolmetin β-D-Glucuronide;Tolmetin β-D-GlucuronideTolmetin β-D-Glucuronide
Tolmetin β-D-Glucuronide has reactive properties with human serum albumin, allowing identification of the binding site and reaction mechanism by tandem mass spectrometry.
价 格:¥电议型 号:T36128产 地:中国大陆
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T36071Silodosin Glucuronide (sodium salt);Silodosin Glucuronide (sodium salt)Silodosin Glucuronide (sodium
Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to rats with an LD50 value of 0.347 mg/kg.
价 格:¥电议型 号:T36071产 地:中国大陆
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T36023Formoterol O-β-D-Glucuronide;Formoterol O-β-D-GlucuronideFormoterol O-β-D-Glucuronide
Formoterol O-β-D-glucuronide is a metabolite of formoterol .
价 格:¥电议型 号:T36023产 地:中国大陆
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T35952all-trans Retinoyl β-D-Glucuronide;all-trans Retinoyl β-D-Glucuronideall-trans Retinoyl β-D-Glucuron
all-trans Retinoyl β-D-glucuronide is a metabolite of all-trans retinoic acid formed by the UDP-glucuronosyltransferase (UGT) system. It is rapidly converted to all-trans retinoic acid following in vitro or in vivo administration.
价 格:¥电议型 号:T35952产 地:中国大陆
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T35845(R,S)-Carvedilol Glucuronide;(R,S)-Carvedilol Glucuronide(R,S)-Carvedilol Glucuronide
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. (R)-Carvedilol glucuronide is formed via glucuronidation of (R)-carvedilol by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1 and UGT2B4. (S)-Carvedilol glucuronide is formed via glucuronidation of (S)-carvedilol by UGT2B4 and UGT2B7.
价 格:¥电议型 号:T35845产 地:中国大陆
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T357204’-hydroxy Atomoxetine Glucuronide (hydrate);4’-hydroxy Atomoxetine Glucuronide (hydrate)4’-hydroxy
4’-hydroxy Atomoxetine glucuronide is a metabolite of the norepinephrine transporter (NET) inhibitor atomoxetine .1It is formed from atomoxetine by glucuronidation of the intermediate metabolite 4-hydroxy atomoxetine.2
价 格:¥电议型 号:T35720产 地:中国大陆
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T356772,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester;2,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester2,3,4
2,3,4-Tri-O-acetyl-β-D-glucuronide methyl ester is a synthetic intermediate in the synthesis of prodrug forms of the antitumor antibiotic daunomycin .1
价 格:¥电议型 号:T35677产 地:中国大陆