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T18914AkaLumine hydrochloride;AkaLumine盐酸盐AkaLumine hydrochloride (1176235-08-7 free base)|||AkaLumine hyd
AkaLumine hydrochloride is a fluorescein analog with a Km value of 2.06 μM for recombinant fluorescent protein.
价 格:¥电议型 号:T18914产 地:中国大陆
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T18899L5(6)-TAMRA hydrochloride(98181-63-6 Free base);化合物5(6)-TAMRA hydrochloride(98181-63-6 Free base)5(6)
5(6)-TAMRA hydrochloride(98181-63-6 Free base) contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid.
价 格:¥电议型 号:T18899L产 地:中国大陆
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T18891L5-TAMRA chloride(91809-66-4 free base);化合物5-TAMRA chloride5-TAMRA chloride(91809-66-4 free base)
5-TAMRA can produce bright, pH insensitive orange fluorescence (Ex/ Em= 546 / 579nm), and has good photostability
价 格:¥电议型 号:T18891L产 地:中国大陆
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T1871LGBR 12935;化合物 T1871LGBR-12935 free base|||GBR12935|||GBR-12935;GBR-12935 free base|||GBR12935|||GBR-
GBR-12935 is a piperazine derivative. It is an effective and selective dopamine reuptake inhibitor. GBR-12935 is now widely used in animal research into Parkinson´s disease and the dopamine pathways in the brain.
价 格:¥电议型 号:T1871L产 地:中国大陆
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T18663(S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base);化合物 T18663(S,R,S)-AHPC-C3-NH2 TFA|||VH032-C3-NH2 TF
(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852. UNC6852 is an EED-targeted bivalent chemical degrader[1].
价 格:¥电议型 号:T18663产 地:中国大陆
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T17923(S,R,S)-AHPC-PEG3-NH2;化合物 T17923E3 ligase Ligand-Linker Conjugates 5 Free Base|||VH032-PEG3-NH2|||VH
(S,R,S)-AHPC-PEG3-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, incorporating the (S,R,S)-AHPC VHL ligand and a 3-unit PEG linker, which are utilized in PROTAC technology.
价 格:¥电议型 号:T17923产 地:中国大陆
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T17731LCL2A-SN-38 DCA 1279680-68-0(free base);化合物CL2A-SN-38 DCACL2A-SN-38 DCA 1279680-68-0(free base)
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a noncleavable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable t
价 格:¥电议型 号:T17731L产 地:中国大陆
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T17696BRD7-IN-1 free base;化合物 T17696BRD7-IN-1 free base
BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), interacts with a VHL ligand through a linker, constituting the PROTAC VZ185 (targeting BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively)[1].
价 格:¥电议型 号:T17696产 地:中国大陆
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T1734LRizatriptan化合物 T1734LMK 462 free base|||Risatriptan
Rizatriptan is an agonist of the serotonin-1b and serotonin-1d receptor.
价 格:¥电议型 号:T1734L产 地:中国大陆
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T17257LWR99210 hydrochloride(47326-86-3 free base);化合物WR99210 hydrochlorideWR99210 hydrochloride(47326-86-3
WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
价 格:¥电议型 号:T17257L产 地:中国大陆
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T17219Vatalanib free base;瓦他拉尼碱Vatalanib free base
Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).
价 格:¥电议型 号:T17219产 地:中国大陆
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T16879LSHU 9119 acetate;化合物SHU 9119 acetateSHU 9119 acetate (168482-23-3 free base);SHU 9119 acetate (16848
SHU 9119 acetate is a well-known antagonist of human melanocortin 3 and 4 (hMC3R, hMC4R) receptors and a partial hMC5R agonist. The IC50 values of human MC3R, MC4R and MC5R is 0.23, 0.06, and 0.09 nM respectively.
价 格:¥电议型 号:T16879L产 地:中国大陆
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T16790LRotigaptide TFA(355151-12-1 free base);化合物Rotigaptide TFARotigaptide TFA;Rotigaptide TFA
Rotigaptide TFA(355151-12-1 free base) is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide TFA(355151-12-1 free base) prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress.
价 格:¥电议型 号:T16790L产 地:中国大陆
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T16743LRhodamine 123 free base;化合物 T16743LRhodamine 123 free base
The laser dye rhodamine 123 inhibit mitochondrion function.
价 格:¥电议型 号:T16743L产 地:中国大陆
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T16704LQuilseconazole Formic acid(1340593-70-5 Free base);化合物 Quilseconazole Formic acid(1340593-70-5 Free
Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.
价 格:¥电议型 号:T16704L产 地:中国大陆
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T16286Nelonemdaz;化合物 NelonemdazSalfaprodil free base|||Neu2000;Salfaprodil free base|||Neu2000
Nelonemdaz (Neu2000) is an NMDA receptor antagonist with antioxidant activity and neuroprotective activity used in the study of cerebral infarction reperfusion injury and acute ischemic stroke.
价 格:¥电议型 号:T16286产 地:中国大陆
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T16103ML-9 Free Base;化合物 T16103ML-9 Free Base
ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 (free base) causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
价 格:¥电议型 号:T16103产 地:中国大陆
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T16090LMK-0773 FA;MK-0773 甲酸盐MK-0773 FA (606101-58-0 Free base);MK-0773 FA (606101-58-0 Free base)
MK-0773 FA (MK-0773 FA (606101-58-0 Free base)) is a selective androgen receptor modulator with an IC50 value of 6.6 nM for AR, which can be used for the prevention and treatment of cancer-related muscle wasting.
价 格:¥电议型 号:T16090L产 地:中国大陆
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T16083Mizagliflozin;化合物MizagliflozinGSK-1614235 free base|||KGA-3235 free base|||DSP-3235 free base;GSK-16
Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation.
价 格:¥电议型 号:T16083产 地:中国大陆
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T15805LLY2510924 acetate(1088715-84-7 free base);化合物LY2510924 acetateLY2510924 acetate(1088715-84-7 free ba
Ly2510924 acetate is an potent and selective CXCR4 antagonist. It prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM.
价 格:¥电议型 号:T15805L产 地:中国大陆