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T13342LWIN site inhibitor 1 TFA (2407457-36-5 free base);化合物 T13342LWIN site inhibitor 1 TFA;WIN site inhib
WIN site inhibitor 1 TFA is a WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5) inhibitor (Kd: 0.1 nM).
价 格:¥电议型 号:T13342L产 地:中国大陆
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T13330WAY-213613 hydrochloride;化合物WAY-213613 hydrochlorideWAY-213613 hydrochloride (868359-05-1 free base)
WAY-213613 hydrochloride is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC 50 of 85 nM. WAY-213613 hydrochloride inhibits EAAT1 and EAAT3 with IC50 values of 5 and 3.8 microM, respectively. WAY-213613 hydrochloride shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function and can be used for the research of central nervous system [1] [2].
价 格:¥电议型 号:T13330产 地:中国大陆
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T13277Valategrast;化合物 T13277R-411 free base;R-411 free base
Valategrast is a potent and orally active dual antagonist of integrin α4β1 (VLA-4) and α4β7, with the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment.
价 格:¥电议型 号:T13277产 地:中国大陆
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T13254LUNC10217938A HCl;化合物UNC10217938A盐酸盐UNC10217938A HCl(1347749-97-6 Free base)|||UNC7938 HCl;UNC102179
UNC10217938A HCl (UNC7938 HCl) is a 3-deazapteridine analog. UNC10217938A HCl exhibits strong oligonucleotide enhancing effects. UNC10217938A HCl can modulate their intracellular trafficking and release from endosomes, leading to enhance oligonucleotides effects. UNC10217938A HCl also enhances the effects of siRNA and antisense oligonucleotides.
价 格:¥电议型 号:T13254L产 地:中国大陆
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T13214LTRPV4 agonist-1 free base;化合物TRPV4 agonist-1 free baseOUN67600;OUN67600
TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).
价 格:¥电议型 号:T13214L产 地:中国大陆
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T13142LTheodrenaline hydrochloride;茶碱那林盐酸盐Theodrenaline hydrochloride(13460-98-5 Free base);Theodrenaline h
Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.
价 格:¥电议型 号:T13142L产 地:中国大陆
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T13112L1Tat-NR2B9c acetate;化合物Tat-NR2B9c acetateTat-NR2B9c acetate (500992-11-0 Free base)|||NA-1 acetate;Ta
Tat-NR2B9c acetate (NA-1 acetate) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c acetate disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c acetate also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.
价 格:¥电议型 号:T13112L1产 地:中国大陆
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T13102LTCMDC-135051 TFA (2413716-15-9 free base);化合物 T13102LTCMDC-135051 TFA;TCMDC-135051 TFA
TCMDC-135051 TFA is a highly selective and potent inhibitor of protein kinase PfCLK3.
价 格:¥电议型 号:T13102L产 地:中国大陆
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T13085LTargaprimir-96 TFA (1655508-14-7 free base);化合物 T13085LTargaprimir-96 TFA;Targaprimir-96 TFA
Targaprimir-96 TFA is a potent microRNA-96 (miR-96) processing inhibitor.
价 格:¥电议型 号:T13085L产 地:中国大陆
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T13073LTaltobulin hydrochloride (228266-40-8 free base);化合物 T13073LSPA-110 hydrochloride|||Taltobulin hydro
Taltobulin hydrochloride is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
价 格:¥电议型 号:T13073L产 地:中国大陆
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T13056T-448 free base;化合物 T13056T-448 free base
T-448 free base is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).
价 格:¥电议型 号:T13056产 地:中国大陆
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T13049LSynucleozid hydrochloride (502139-01-7 free base);化合物 T13049LSynucleozid hydrochloride|||NSC 377363
Synucleozid hydrochloride is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.
价 格:¥电议型 号:T13049L产 地:中国大陆
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T13014LSTING agonist-3 trihydrochloride;化合物 T13014LSTING agonist-3 trihydrochloride (2138299-29-1 free base
STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer.
价 格:¥电议型 号:T13014L产 地:中国大陆
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T12992SPR741 acetate;醋酸盐SPR741 acetate|||NAB741 acetate|||SPR741 acetate (1179330-52-9 free base);SPR741 a
SPR741 acetate is a cationic peptide derived from polymyxin B. It exhibits antimicrobial activity against gram-negative bacteria by inhibiting severe gram-negative bacterial sensory by increasing the permeability of the outer membrane of gram-negative bacteria.SPR741 acetate is often used in conjunction with antibiotics for the treatment of a number of diseases.
价 格:¥电议型 号:T12992产 地:中国大陆
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T12945SNT-207858 free base;化合物 T12945SNT-207858 free base
SNT-207858 free base is a selective, blood brain barrier penetrating, potent and orally active antagonist of melanocortin-4 (MC-4) receptor(IC50 of 22 nM (binding) and 11 nM (function), on the MC-4 receptor).
价 格:¥电议型 号:T12945产 地:中国大陆
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T12942LSN50 acetate (213546-53-3 free base);化合物SN50 acetateSN50 acetate (213546-53-3 free base)
SN50 acetate is a cell permeable inhibitor of NF-κB translocation.
价 格:¥电议型 号:T12942L产 地:中国大陆
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T12932SM-164 Hydrochloride (957135-43-2 free base);化合物 T12932SM-164 Hydrochloride;SM-164 Hydrochloride
SM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains(IC50 value of 1.39 nM) and functions as an extremely potent antagonist of XIAP.
价 格:¥电议型 号:T12932产 地:中国大陆
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T12923(Rac)-SIS3 free base;化合物 T12923(Rac)-SIS3 free base
SIS3 free base is a potent and selective Smad3 phosphorylation inhibitor. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1.
价 格:¥电议型 号:T12923产 地:中国大陆
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T12896LShepherdin 79-87 acetate;化合物Shepherdin 79-87 acetateShepherdin 79-87 acetate (861224-28-4 free base)
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.
价 格:¥电议型 号:T12896L产 地:中国大陆
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T12882LSetmelanotide Acetate(920014-72-8 free base);化合物Setmelanotide AcetateRM-493 Acetate|||IRC-022493 Ace
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
价 格:¥电议型 号:T12882L产 地:中国大陆