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T11154LEG01377 2HCl;EG01377二盐酸盐EG01377 2HCl(2227996-00-9 Free base);EG01377 2HCl(2227996-00-9 Free base)
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.
价 格:¥电议型 号:T11154L产 地:中国大陆
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T11128Dutogliptin;化合物 T11128PHX-1149 free base;PHX-1149 free base
Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
价 格:¥电议型 号:T11128产 地:中国大陆
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T11119Duocarmycin DM free base;化合物 T11119Duocarmycin;Duocarmycin
Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) . Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.
价 格:¥电议型 号:T11119产 地:中国大陆
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T11095DREADD agonist 21 dihydrochloride;化合物 T11095DREADD agonist 21 dihydrochloride (56296-18-5 free base)
DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].
价 格:¥电议型 号:T11095产 地:中国大陆
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T11090L1Aldoxorubicin hydrochloride;化合物Aldoxorubicin盐酸盐Aldoxorubicin hydrochloride (1361644-26-9 Free base);
Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibits potent antitumor activities in various cancer cell lines and in murine tumor models.
价 格:¥电议型 号:T11090L1产 地:中国大陆
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T11087DOV-216,303 Free Base;化合物DOV-216,303 Free BaseDOV-216303;DOV-216303
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.
价 格:¥电议型 号:T11087产 地:中国大陆
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T11052LDisitertide acetate;地司特泰醋酸盐P144 acetate|||Disitertide acetate(272105-42-7 Free base);P144 acetate|||
Disitertide acetate (P144 acetate) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide acetate is also a PI3K inhibitor and an apoptosis inducer.
价 格:¥电议型 号:T11052L产 地:中国大陆
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T11048LDIPQUO hydrochloride;化合物DIPQUO盐酸盐DIPQUO hydrochloride(1269365-82-3 Free base);DIPQUO hydrochloride(1
DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
价 格:¥电议型 号:T11048L产 地:中国大陆
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T10994LDeltasonamide 2 hydrochloride;化合物 T10994LDeltasonamide 2 hydrochloride (2088485-34-9 free base);Delt
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.
价 格:¥电议型 号:T10994L产 地:中国大陆
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T10988LDegarelix acetate(214766-78-6 free base);化合物Degarelix acetateDegarelix acetate(214766-78-6 free base
Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .
价 格:¥电议型 号:T10988L产 地:中国大陆
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T10937LD-JNKI-1 acetate;化合物D-JNKI-1 acetateD-JNKI-1 acetate(1445179-97-4 Free base)|||AM-111 acetate;D-JNKI
D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.
价 格:¥电议型 号:T10937L产 地:中国大陆
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T10896LCSRM617 hydrochloride;盐酸CSRM617CSRM617 hydrochloride(787504-88-5 Free base);CSRM617 hydrochloride(78
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the mouse model of prostate cancer [1]
价 格:¥电议型 号:T10896L产 地:中国大陆
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T10893CS-722 Free base;化合物CS-722 Free baseCS-722 Free base
CS-722 Free base is a synthetic central muscle relaxant with muscle relaxant activity and inhibitory effect on spinal reflex. CS-722 Free base may inhibit spontaneous inhibitory post-synaptic current and excitatory post-synaptic current in hippocampal culture by inhibiting sodium current and calcium current.
价 格:¥电议型 号:T10893产 地:中国大陆
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T10892CS-003 Free base;化合物 T10892CS-003 Free base
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 nM and 0.54 nM, respectively And 0.74 nM. CS-003 free base (CS-003) has therapeutic effects on neurokinin-related respiratory diseases.
价 格:¥电议型 号:T10892产 地:中国大陆
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T10883LCRA-026440 hydrochloride;化合物CRA-026440盐酸盐CRA-026440 hydrochloride(847460-34-8 Free base);CRA-026440
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.
价 格:¥电议型 号:T10883L产 地:中国大陆
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T10840CM-579 trihydrochloride (1846570-40-8 free base);化合物 T10840CM-579 trihydrochloride;CM-579 trihydroch
CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cells.
价 格:¥电议型 号:T10840产 地:中国大陆
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T10835L1Cletoquine hydrochloride;盐酸氯托喹Cletoquine hydrochloride( 4298-15-1 Free base);Cletoquine hydrochlorid
Cletoquine hydrochloride is a major active metabolite of Hydroxychloroquine. Cletoquine hydrochloride is a Chloroquine derivative and exhibits the ability to against the chikungunya virus (CHIKV). Cletoquine hydrochloride exhibits antimalarial effects.
价 格:¥电议型 号:T10835L1产 地:中国大陆
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T10829CKI-7 free base;化合物 T10829CKI-7;CKI-7
CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
价 格:¥电议型 号:T10829产 地:中国大陆
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T10820L1Ciraparantag acetate;化合物Ciraparantag acetateCiraparantag acetate(1438492-26-2 Free base);Ciraparanta
Ciraparantag acetate, an anticoagulant reversal agent, is a small molecule specifically designed to bind noncovalently by charge-charge interaction to unfractionated heparin and low-molecular-weight heparin.?It shows binding characteristics that are similar to those of direct oral anticoagulants (DOACs).
价 格:¥电议型 号:T10820L1产 地:中国大陆
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T10809LCHPG hydrochloride;化合物CHPG盐酸盐CHPG hydrochloride(170846-74-9 Free base);CHPG hydrochloride(170846-74-
CHPG hydrochloride is a selective agonist of mGluR5.
价 格:¥电议型 号:T10809L产 地:中国大陆