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T10468Elimusertib hydrochloride(1876467-74-1 free base);化合物 Elimusertib hydrochlorideBAY-1895344 hydrochlo
Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor with anti-tumor activity.
价 格:¥电议型 号:T10468产 地:中国大陆
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T10463LBax inhibitor peptide V5 acetate;化合物T10463LBax inhibitor peptide V5 acetate(579492-81-2 free base);B
Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
价 格:¥电议型 号:T10463L产 地:中国大陆
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T10443Aβ42-IN-1 free base;化合物 T10443Aβ42-IN-1 free base
Aβ42-IN-1 free base (compound 1v), an orally active γ-secretase modulator with high brain exposure, effectively lowers Aβ42 levels, exhibiting an IC 50 of 0.091 μM, and significantly diminishes brain Aβ42 levels in mice. Given these properties, Aβ42-IN-1 free base represents a potential disease-modifying agent for Alzheimer’s disease [1].
价 格:¥电议型 号:T10443产 地:中国大陆
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T10436LAZD4573 HCl (2057509-72-3 free base);化合物 T10436LAZD4573 hydrochloride|||AZD4573|||AZD4573 HCl|||AZD-
AZD-4573 is a selective and short-acting inhibitor of the serine/threonine cyclin-dependent kinase 9, the catalytic subunit of the RNA polymerase II elongation factor positive transcription elongation factor b. It also has a potential antineoplastic activity.
价 格:¥电议型 号:T10436L产 地:中国大陆
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T10395ATM-3507 trihydrochloride (1861449-70-8 free base);化合物 T10395ATM-3507 trihydrochloride;ATM-3507 trih
ATM-3507 trihydrochloride is a potent tropomyosin inhibitor (IC50s: 3.83-6.84 μM in human melanoma cell lines).
价 格:¥电议型 号:T10395产 地:中国大陆
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T10394LATB107 hydrochloride;化合物ATB107盐酸盐ATB107 hydrochloride(455325-51-6 Free base);ATB107 hydrochloride(45
ATB107 hydrochloride is a novel and potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM.
价 格:¥电议型 号:T10394L产 地:中国大陆
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T10382AS2863619 free base;化合物 T10382AS2863619 free base
AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells. It is a potent, orally active CDK8 and CDK19 inhibitor (IC50s: 0.61 nM and 4.28 nM). STAT5 activation enhanced by AS2863619 free base inhibition of CDK8/19, which consequently activates the Foxp3 gene.
价 格:¥电议型 号:T10382产 地:中国大陆
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T10366LArg-Gly-Asp-Ser acetate;化合物Arg-Gly-Asp-Ser acetateArg-Gly-Asp-Ser acetate(91037-65-9 free base);Arg-
Arg-Gly-Asp-Ser acetate is an integrin binding sequence that directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1. Arg-Gly-Asp-Ser acetate inhibits integrin receptor function.
价 格:¥电议型 号:T10366L产 地:中国大陆
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T10353APX-115 free base;化合物APX-115 free baseEwha-18278 free base;Ewha-18278 free base
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.
价 格:¥电议型 号:T10353产 地:中国大陆
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T10347LApidaecin IB acetate;化合物Apidaecin IB acetateApidaecin IB acetate (123276-94-8 Free base);Apidaecin I
Apidaecin IB acetate is an insect antibacterial peptide. The minimum concentration of apidaecin IB acetate against Escherichia coli (E. coli ML35, o18k1h7 and ATCC 25922) is 8 μM.
价 格:¥电议型 号:T10347L产 地:中国大陆
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T10338Antisauvagine-30 TFA (220673-95-0 free base);化合物 T10338Antisauvagine-30 TFA|||aSvg-30 TFA;Antisauvag
Antisauvagine-30 TFA (aSvg-30 TFA) is a highly selective and competitive antagonist of CRF2 receptor peptidic. It shows a Kd of 1.4 nM and 150 nM for mCRFR2β and CRFR1, respectively.
价 格:¥电议型 号:T10338产 地:中国大陆
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T10322LAngiotensin III TFA (12687-51-3 free base);化合物 T10322LAngiotensin III TFA;Angiotensin III TFA
Angiotensin III TFA is an agonist of angiotensin 1 (AT1) and AT2 receptor.
价 格:¥电议型 号:T10322L产 地:中国大陆
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T10298L2AMG-548 dihydrochloride (864249-60-5 free base);化合物 T10298L2AMG-548 dihydrochloride;AMG-548 dihydroc
AMG-548 dihydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50: 3 nM).
价 格:¥电议型 号:T10298L2产 地:中国大陆
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T10298AMG-548 hydrochloride (864249-60-5 free base);化合物 T10298AMG-548 hydrochloride;AMG-548 hydrochloride
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50: 3 nM).
价 格:¥电议型 号:T10298产 地:中国大陆
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T10290LAlpertine HCl;阿尔哌汀盐酸盐Win 31665 HCl|||Alpertine HCl(27076-46-6 Free base);Win 31665 HCl|||Alpertine H
Alpertine HCl is a small molecule compound with anti-neuropathic properties.
价 格:¥电议型 号:T10290L产 地:中国大陆
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T10276LAKT Kinase Inhibitor HCl;AKT Kinase抑制剂盐酸盐AKT Kinase Inhibitor HCl(842148-40-7 Free base);AKT Kinase
AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity.
价 格:¥电议型 号:T10276L产 地:中国大陆
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T10258AFP464 free base;化合物 T10258NSC710464 free base;NSC710464 free base
AFP464 (NSC710464) free base is an active HIF-1α inhibitor (IC50: 0.25 μM) and a potent aryl hydrocarbon receptor (AhR) activator.
价 格:¥电议型 号:T10258产 地:中国大陆
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T10217Abarelix Acetate (183552-38-7 free base);化合物 T10217PPI 149 Acetate|||Abarelix Acetate;PPI 149 Acetat
Abarelix (PPI 149; R 3827) Acetate is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research.
价 格:¥电议型 号:T10217产 地:中国大陆
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T10204A-317491 sodium salt hydrate;化合物 T10204A-317491 sodium salt hydrate (475205-49-3 free base);A-317491
A-317491 sodium salt hydrate is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors.
价 格:¥电议型 号:T10204产 地:中国大陆
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T0785LDexchlorpheniramine free base;化合物 T0785LPolaramine|||Dexchlorpheniramine Maleate|||Mylaramine;Polara
Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.
价 格:¥电议型 号:T0785L产 地:中国大陆