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T12056MK-0941 free base;MK-0941 FREE BASEMK-0941 free base
MK-0941 free base is an orally active glucokinase activator, exhibiting strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes.
价 格:¥电议型 号:T12056产 地:中国大陆
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T12054LMK-0249 FA;MK-0249 甲酸盐MK-0249 FA(862309-06-6 Free base);MK-0249 FA(862309-06-6 Free base)
MK-0249 FA is an orally active, selective and potent histamine H3 inverse agonist for the study of attention deficit, hyperactivity disorder neurodivergent and cognitive disorders in adults.
价 格:¥电议型 号:T12054L产 地:中国大陆
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T11948Masupirdine free base;化合物 MasupirdineMasupirdine|||SUVN-502 free base;Masupirdine|||SUVN-502 free ba
Masupirdine free base (SUVN-502 free base) is an orally available 5-HT6 receptor antagonist that crosses the blood-brain barrier and has a Ki value of 2.04 nM for the human 5-HT6 receptor.Masupirdine free base is potent and selective with multiple targets. Masupirdine free base is highly potent, selective and inhibits multiple targets.Masupirdine free base can be used in the study of neurological disorders such as Alzheimer´s disease.
价 格:¥电议型 号:T11948产 地:中国大陆
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T11856LIT-001 free base;化合物 T11856LIT-001 free base
LIT-001 free base improves social interaction in a mouse model of autism. LIT-001 free base is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM).
价 格:¥电议型 号:T11856产 地:中国大陆
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T11839LLesopitron HCl;来索吡琼盐酸盐Lesopitron HCl(132449-89-9 Free base);Lesopitron HCl(132449-89-9 Free base)
Lesopitron HCl is a 5-HT1A receptor agonist with anxiolytic effects that reverses dark avoidance behavior associated with cocaine withdrawal in mice.
价 格:¥电议型 号:T11839L产 地:中国大陆
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T11792KW-8232 free base;化合物 T11792KW-8232 free base
KW-8232 free base can reduces the biosynthesis of PGE2, is an anti-osteoporotic agent.
价 格:¥电议型 号:T11792产 地:中国大陆
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T11750LKDOAM-25 trihydrochloride (2230731-99-2 free base);化合物 T11750LKDOAM-25 trihydrochloride;KDOAM-25 tri
KDOAM-25 trihydrochloride increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells. KDOAM-25 trihydrochloride is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively.
价 格:¥电议型 号:T11750L产 地:中国大陆
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T11731LJTV-519 Formate;化合物JTV-519 FormateJTV-519 Formate (145903-06-6 Free base);JTV-519 Formate (145903-06
JTV-519 Formate is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA). JTV-519 Formate is also a partial agonist of ryanodine receptors in striated muscle. JTV-519 Formate exhibits antiarrhythmic and cardioprotective properties.
价 格:¥电议型 号:T11731L产 地:中国大陆
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T11731JTV-519 free base;化合物 T11731K201 free base;K201 free base
JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and serves as a partial agonist of ryanodine receptors in striated muscle.
价 格:¥电议型 号:T11731产 地:中国大陆
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T11719JMV 2959 hydrochloride (925238-89-7 free base);化合物JMV 2959 hydrochlorideJMV 2959 hydrochloride;JMV 2
JMV 2959 hydrochloride (925238-89-7 free base) is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
价 格:¥电议型 号:T11719产 地:中国大陆
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T11710LJAK-IN-5 hydrochloride;化合物JAK-IN-5 hydrochlorideJAK-IN-5 hydrochloride(2096999-92-5 Free base);JAK-I
JAK-IN-5 hydrochloride is a JAK inhibitor [1].
价 格:¥电议型 号:T11710L产 地:中国大陆
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T11688ITI-214 free base;化合物 T11688ITI214 free base;ITI214 free base
ITI-214 free base is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).
价 格:¥电议型 号:T11688产 地:中国大陆
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T11597LIACS-9571 Hydrochloride (1800477-30-8 free base);化合物 T11597LIACS-9571 Hydrochloride|||ASIS-P040 Hydr
IACS-9571 Hydrochloride is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).
价 格:¥电议型 号:T11597L产 地:中国大陆
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T11545LhDDAH-1-IN-2 sulfate (2408834-77-3 free base);化合物 T11545LhDDAH-1-IN-2 sulfate;hDDAH-1-IN-2 sulfate
hDDAH-1-IN-2 sulfate is an orally active human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) inhibitor.
价 格:¥电议型 号:T11545L产 地:中国大陆
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T11534LHaemanthamine hydrochloride (466-75-1 free base);化合物 T11534LHaemanthamine hydrochloride;Haemanthamin
Haemanthamine hydrochloride is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiviral, antioxidant, and anticonvulsant activities.
价 格:¥电议型 号:T11534L产 地:中国大陆
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T11519GW768505A free base;化合物 T11519GW768505A free base
GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2 (pIC50: 7.81 for VEGFR2) with anti-angiogenic activity.
价 格:¥电议型 号:T11519产 地:中国大陆
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T11510Guanfu base I;化合物 T11510Acorine;Acorine
Guanfu base I is an active metabolite of Guanfu base A, isolated from Aconitum coreanum. It have a potent anti-arrhythmic effect.
价 格:¥电议型 号:T11510产 地:中国大陆
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T11509Guanfu base H;化合物 T11509Atisinium chloride;Atisinium chloride
Guanfu base H is a diterpenoid alkaloid isolated from Aconitum coreanum. It has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 (IC50s: 4 μM and 3.6 μM).
价 格:¥电议型 号:T11509产 地:中国大陆
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T11490LGSK2945 hydrochloride (1438071-12-5 free base);化合物 T11490LGSK2945 hydrochloride;GSK2945 hydrochlorid
GSK2945 hydrochloride is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist (EC50s: 21.5 μM and 20.8 μM). It enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism.
价 格:¥电议型 号:T11490L产 地:中国大陆
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T11478LGSK1521498 free base;化合物 T11478LGSK1521498 free base
GSK1521498 free base is a potent and selective antagonist of the μ-opioid receptor. GSK1521498 free base also has the potential for disorders of compulsive consumption of food, alcohol, and drugs.
价 格:¥电议型 号:T11478L产 地:中国大陆