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T4276Hydroxyfasudil Hydrochloride羟基法舒地尔盐酸盐;RHO-激酶抑制剂;Hydroxyfasudil (HA-1100) HCl;HA 1100 hydrochloride
Hydroxyfasudil hydrochloride is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).
价 格:¥电议型 号:T4276产 地:中国大陆
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T4236AR-M 1000390 hydrochlorideARM-390 HCl;ARM390 Hydrochloride
AR-M 1000390 (hydrochloride), also known as ARM-390, is a low-internalizing nonpeptidic δ-selective opioid receptor agonist; derivative of SNC 80. Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain pe
价 格:¥电议型 号:T4236产 地:中国大陆
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T41003KG5KG5
KG5 is an orally active dual PDGFRβ and B-Raf allosteric inhibitor. KG5 also inhibits Flt3 , KIT and c-Raf . KG5 has anticancer, antiangiogenic activities.
价 格:¥电议型 号:T41003产 地:中国大陆
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T4100AS8351AS 8351;NSC51355;AS-8351
AS-8351 is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-10198409 to induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.
价 格:¥电议型 号:T4100产 地:中国大陆
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T4042Talabostat mesylatePT100;Val-boroPro
Talabostat mesylate is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 nM), including tumor-associated fibroblast activation protein. This agent may also stimulate the production of colony stimulating factors, such as g
价 格:¥电议型 号:T4042产 地:中国大陆
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T3S2100(-)-Securinine一叶秋碱;Securinine
(-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist.
价 格:¥电议型 号:T3S2100产 地:中国大陆
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T3S0738yangonin甲氧醉椒素;Y100550
1. Yangonin is a novel CB receptor ligand, it exhibits affinity for the human recombinant CB receptor. 2. Yangonin could be a valuable candidate for the intervention of NF-κB-dependent pathological conditions such as inflammation.
价 格:¥电议型 号:T3S0738产 地:中国大陆
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T3797IsosilybinIsosilibinin;Silybin B;Silymarin;Isosilybinin;Q-100795;异水飞蓟宾
Isosilybin and Silybin might be suitable candidates to design potent PXR antagonists to prevent drug-drug interactions via CYP3A4 in cancer patients.
价 格:¥电议型 号:T3797产 地:中国大陆
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T3625Bempedoic acidESP-55016;ETC-1002;ETC 1002;ETC1002
ETC-1002, also known as ESP-55016 and Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic acid i
价 格:¥电议型 号:T3625产 地:中国大陆
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T3424EzutromidSMT C1100;BMN 195;VOX-C1100;依珠曲米
Ezutromid is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, increasing both utrophin mRNA and protein. Through this action, Ezutromid incre
价 格:¥电议型 号:T3424产 地:中国大陆
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T3403Glabridin光甘草定;Q-100692;KB-289522;LS-176045
Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hype
价 格:¥电议型 号:T3403产 地:中国大陆
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T3100GSK-J4GSK J4 HCl;GSK J4
GSK-J4 is a potent H3K27me3 demethylase inhibitor, with IC50s of 8.6 μM and 6.6 μM towards KDM6B and KDM6A respectively. It is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM in a cell-free assay and inactiv
价 格:¥电议型 号:T3100产 地:中国大陆
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T304810058-F4c-Myc Inhibitor
10058-F4 is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; induces cell-cycle arrest and apoptosis.
价 格:¥电议型 号:T3048产 地:中国大陆
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T3001Honokiol和厚朴酚;NSC 293100
Honokiol is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
价 格:¥电议型 号:T3001产 地:中国大陆
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T2S1008Oxysophoridine氧化槐定碱;Sophoridine N-oxide
Oxysophoridine has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, that the effect may be due to its ability to inhibit oxid
价 格:¥电议型 号:T2S1008产 地:中国大陆
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T2923ApremilastCC-10004;阿普斯特;阿普司特
Apremilast (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.
价 格:¥电议型 号:T2923产 地:中国大陆
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T2672TG100-115
TG100-115 is a PI3Kγ/δ inhibitor (IC50: 83/235 nM), with fewer effects on PI3Kα/β.
价 格:¥电议型 号:T2672产 地:中国大陆
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T2631WAY-100635 Maleate
WAY-100635 is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).
价 格:¥电议型 号:T2631产 地:中国大陆