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T8341QX 314;化合物QX 314QX-314;QX-314
QX 314 (Lidocaine N-ethyl bromide) is a blocker of non-membrane-permeable,and Inhibits Acid-Induced Activation of Esophageal Nociceptive C Fiber Neurons.
价 格:¥电议型 号:T8341产 地:中国大陆
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T833144-Methylumbelliferyl palmitate;化合物 4-Methylumbelliferyl palmitate4-Methylumbelliferyl palmitate
4-Methylumbelliferyl palmitate serves as a potent fluorophore to assay acid lipase activity in human leukocytes, with its fluorescence significantly affected by acidity and solvent properties. In near-neutral aqueous solutions, it predominates in a neutral molecular form, emitting strong fluorescence at 445 nm, whereas in weakly alkaline solutions, it primarily exists in an anionic form, resulting in even stronger fluorescence at the same wavelength [1] [2].
价 格:¥电议型 号:T83314产 地:中国大陆
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T8329AR 231453;化合物AR 231453AR 231453
AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.
价 格:¥电议型 号:T8329产 地:中国大陆
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T83149Ajugose;化合物 AjugoseAjugose
Ajugose, a hexasaccharide, is isolatable from the seeds of Vigna mungo L. [1].
价 格:¥电议型 号:T83149产 地:中国大陆
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T83148Alarin (human);化合物 Alarin (human)Alarin (human)
Alarin (human) is a hypothalamic neuropeptide from the galanin peptide family. It contains the signal sequence of the GALP precursor and the initial five amino acids (aa) of the mature GALP [1].
价 格:¥电议型 号:T83148产 地:中国大陆
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T83147Albinterferon alfa-2B;化合物 Albinterferon alfa-2Balb-IFN;alb-IFN
Albinterferon alfa-2B (alb-IFN), a recombinant protein, comprises interferon alfa-2b conjugated to human albumin and is utilized in the study of chronic hepatitis C [1].
价 格:¥电议型 号:T83147产 地:中国大陆
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T83146ALK-IN-27;化合物 ALK-IN-27ALK-IN-27
ALK-IN-27 (compound 1) is a potent ALK inhibitor exhibiting antitumor activity, with an IC50 of 2.7 nM in Ba/F3 CLIP1-LTK cells [1].
价 格:¥电议型 号:T83146产 地:中国大陆
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T83145Allo-aca TFA;化合物 Allo-aca TFAAllo-aca TFA
Allo-aca TFA, a potent and specific leptin receptor antagonist peptide, inhibits leptin signaling and function across various in vitro and in vivo models [1] [2].
价 格:¥电议型 号:T83145产 地:中国大陆
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T83144allo-Aloeresin D;化合物 allo-Aloeresin Dallo-Aloeresin D
Allo-Aloeresin D, a chromone glycoside, has been isolated from species of Aloe [1].
价 格:¥电议型 号:T83144产 地:中国大陆
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T83143Alloferon 1;化合物 Alloferon 1Alloferon 1
Alloferon 1, a peptide derived from the blood of the blow fly Calliphora vicina (Diptera) [1] [2] [3], exhibits antiviral and antitumoral properties. It activates natural cytotoxicity of human peripheral blood lymphocytes, induces IFN synthesis, and enhances resistance against viral and tumor challenges in mice. Additionally, Alloferon 1 demonstrates anti-inflammatory effects in λ-carrageenan-induced paw edema models.
价 格:¥电议型 号:T83143产 地:中国大陆
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T83142Alloferon 2;化合物 Alloferon 2Alloferon 2
Alloferon 2, an antiviral and antitumoral peptide, can be isolated from the hemolymph of the blow fly Calliphora vicina (Diptera) [1].
价 格:¥电议型 号:T83142产 地:中国大陆
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T83141Alnuctamab;化合物 AlnuctamabEM901|||CC-93269;EM901|||CC-93269
Alnuctamab (EM901) is a humanized, asymmetric two-arm IgG T-cell engager (TCE) with potential applications in immunological research [1].
价 格:¥电议型 号:T83141产 地:中国大陆
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T8314RP-64477;化合物RP64477RP64477;RP64477
RP-64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.
价 格:¥电议型 号:T8314产 地:中国大陆
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T82314GK444;化合物 GK444GK444
GK444 (Compound 15a), a selective HDAC1/2 inhibitor with IC50 values of 100 nM and 92 nM for HDAC1 and HDAC2 respectively, demonstrates an IC50 of 4.1 μM in Caco-2 cell inhibition. Additionally, GK444 attenuates TGF-β1-induced COL1A1 mRNA expression in primary normal human lung fibroblasts and mitigates Bleomycin-induced lung fibrosis in mice [1].
价 格:¥电议型 号:T82314产 地:中国大陆
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T81314Rademikibart;化合物 RademikibartCBP-201;CBP-201
Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without cross-reactivity to IL-4Rα from other species. It effectively inhibits IL-4 and IL-13-induced STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMCs, showing promise for investigating moderate-to-severe Th2 inflammatory diseases [1].
价 格:¥电议型 号:T81314产 地:中国大陆
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T80314Dermaseptin-S2;化合物 Dermaseptin-S2Dermaseptin-S2
Dermaseptin-S2, an antimicrobial peptide sourced from frog skin, exhibits activity against filamentous fungi [1].
价 格:¥电议型 号:T80314产 地:中国大陆
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T79314PD-L1-IN-3;化合物 PD-L1-IN-3PD-L1-IN-3
PD-L1-IN-3 (Compound 4a) functions as an inhibitor targeting the PD-1/PD-L1 axis, with an IC50 value of 4.97nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1 interaction by binding to the PD-L1 dimer, obstructing PD-1 signaling. This compound is utilized in research pertaining to lung cancer and melanoma [1].
价 格:¥电议型 号:T79314产 地:中国大陆
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T78564Depramine;化合物 DepramineGP 31406;GP 31406
Depramine (GP 31406), a tricyclic antidepressant, exhibits pharmacological activity by inhibiting acetylcholinesterase, Mg^2+-ATPase, and Na^+/K^+ ATPase activity [1] [2].
价 格:¥电议型 号:T78564产 地:中国大陆
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T78314Fianlimab;化合物 FianlimabREGN3767;REGN3767
Fianlimab (REGN3767) is a human monoclonal antibody targeting the LAG-3 immune checkpoint receptor on T cells, exhibiting anti-tumor activity [1].
价 格:¥电议型 号:T78314产 地:中国大陆
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T76314Epobis;化合物 EpobisEpobis
Epobis, a dendrimeric peptide and recombinant form of erythropoietin, acts as a potent erythropoietin receptor agonist. It fosters neuritogenesis in primary motoneurons, reduces TNF release, and effectively crosses the blood-brain barrier. Additionally, Epobis exhibits anti-inflammatory properties and enhances memory [1].
价 格:¥电议型 号:T76314产 地:中国大陆