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T82344Gambogic acid B；化合物 Gambogic acid BGambogic acid B
Gambogic acid B, isolated from Garcinia hanburyi resin, exhibits cytotoxic effects on A549, HCT116, and MDA-MB-231 cell lines with respective IC50 values of 1.60 ?M, 6.88 ?M, and 0.87 ?M [1].
价 格：￥电议型 号：T82344产 地：中国大陆
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T81344Pycnophorin；化合物 PycnophorinPycnophorin
Pycnophorin effectively suppresses Bacillus subtilis and Staphylococcus aureus proliferation, demonstrating identical minimum inhibitory concentration (MIC) values of 25 μM for both bacterial species.
价 格：￥电议型 号：T81344产 地：中国大陆
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T80344Aeschna defensin；化合物 Aeschna defensinAeschna defensin
Aeschna defensin is an antimicrobial peptide sourced from the hemolymph of aquatic dragonfly larvae, exhibiting potent activity against Gram-positive bacteria [1].
价 格：￥电议型 号：T80344产 地：中国大陆
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T79344CDD-1819；化合物 CDD-1819CDD-1819
CDD-1819, a non-covalent and non-peptide compound, serves as a potent SARS-CoV-2 Mpro inhibitor, exhibiting a K i value of 5 nM. It also effectively inhibits the Mpro variants ΔP168, A173V, and ΔP168/A173V [1].
价 格：￥电议型 号：T79344产 地：中国大陆
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T78344Pectinase；化合物 PectinasePectinase
Pectinase, a complex of enzymes, catalyzes the hydrolysis of pectic substances and is predominantly found in microorganisms and higher plants. This enzyme plays a crucial role in cell wall metabolism, cell growth, senescence, fruit ripening, pathogenesis, and the abscission process [1].
价 格：￥电议型 号：T78344产 地：中国大陆
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T77344icFSP1；化合物IcFSP1icFSP1
icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
价 格：￥电议型 号：T77344产 地：中国大陆
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T76858Ascrinvacumab；阿伐苏单抗PF-03446962；PF-03446962
Ascrinvacumab (PF-03446962) is a highly humanized IgG2 monoclonal antibody against ALK-1. Ascrinvacumab has a Kd value of 7 nM for human ALK1. Ascrinvacumab has an inhibitory effect on TGF-β and can be used to study hepatocellular carcinoma (HCC).
价 格：￥电议型 号：T76858产 地：中国大陆
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T76344Agelenin；化合物 AgeleninAgelenin
Agelenin, a polypeptide comprising 35 amino acids, can be isolated from the Agelenidae family spider, Agelena opulenta. This compound exhibits structural similarity to insect-specific calcium channel inhibitors [1].
价 格：￥电议型 号：T76344产 地：中国大陆
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T75344NCT-TFP；化合物 NCT-TFPNCT-TFP
NCT-TFP is PARP probe used to identifying Poly(ADP-ribose) polymerases (PARP) inhibitors[1].
价 格：￥电议型 号：T75344产 地：中国大陆
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T73449CZS-241；化合物 CZS-241CZS-241
CZS-241 is an orally active, selective Polo-like Kinase (PLK) 4 inhibitor with an IC 50 of 2.6 nM that also inhibits TRKA at an IC 50 of 2.74 μM. It induces apoptosis and causes cell cycle arrest at the S/G2 phase, demonstrating potent antiproliferative effectiveness against leukemia cell lines while maintaining safety towards normal cell lines.
价 格：￥电议型 号：T73449产 地：中国大陆
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T73447NP10679；化合物 NP10679NP10679
NP10679 is an orally available, selective, brain-penetrating, potent, and pH-sensitive N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit.NP10679 inhibits histamine H1, hERG channels, and CYP enzymes, and may be useful in the study of epilepsy and ischemic stroke.
价 格：￥电议型 号：T73447产 地：中国大陆
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T73446BI?3231；化合物BI?3231BI?3231
BI?3231 is a selective and potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.
价 格：￥电议型 号：T73446产 地：中国大陆
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T73445TIM-063；化合物 TIM-063TIM-063
TIM-063 is a selective, cell-permeable inhibitor of CaMKK that competes with ATP, directly targeting the catalytic domain of CaMKK. It exhibits K(i) values of 0.35 μM for CaMKKα and 0.2 μM for CaMKKβ, with respective IC(50) values of 0.63 μM and 0.96 μM.
价 格：￥电议型 号：T73445产 地：中国大陆
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T73444BRD7586；化合物 BRD7586BRD7586
BRD7586 represents the smallest known anti-CRISPR, functioning as a cell-permeable, small-molecule inhibitor targeting SpCas9.
价 格：￥电议型 号：T73444产 地：中国大陆
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T73443STL1267；化合物 STL1267STL1267
STL1267, a potent REV-ERB agonist capable of crossing the blood-brain barrier, exhibits a K i value of 0.16 ?M for REV-ERBα without demonstrating cytotoxicity. It effectively inhibits the gene expression of BMAL1.
价 格：￥电议型 号：T73443产 地：中国大陆
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T73442KM04416；化合物 KM04416KM04416
KM04416, a derivative of isothiazolone, effectively functions as a glycerol-3-phosphate dehydrogenase (GPD2) inhibitor. This compound notably restricts the proliferation of PNT1A cells.
价 格：￥电议型 号：T73442产 地：中国大陆
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T73441TBI-166；化合物 TBI-166TBI-166
TBI-166, an orally active riminophenazine analogue, serves as an anti-tuberculosis agent and exhibits fewer adverse reactions compared to its lead compound, Clofazimine [1] [2] [3].
价 格：￥电议型 号：T73441产 地：中国大陆
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T73440ccc_R08；化合物 ccc_R08ccc_R08
ccc_R08 is an orally available HBV cccDNA inhibitor that reduces extracellular levels of HBV DNA, HBsAg, and HBeAg in a dose-dependent manner. ccc_R08 is investigational for use in the treatment of HBV infections. ccc_R08 has been shown to be effective in the treatment of hepatitis C virus (HCV).
价 格：￥电议型 号：T73440产 地：中国大陆
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T7318Elimusertib；化合物BAY-1895344BAY-1895344；BAY-1895344
Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride.
价 格：￥电议型 号：T7318产 地：中国大陆
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T72344KRAS G12C inhibitor 41；化合物 KRAS G12C inhibitor 41KRAS G12C inhibitor 41
KRAS G12C Inhibitor 41 is a potent agent targeting the KRAS G12C mutation within the Ras family of proteins, which are crucial for intracellular signaling related to growth and development. This compound holds significant potential for advancing research in cancers mediated by KRAS G12C.
价 格：￥电议型 号：T72344产 地：中国大陆
