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  • T71459PD 163449；化合物 PD 163449PD 163449

    PD 163449 is a bioactive molecule of 4-pyridone group that inhibits bacterial type IIA topoisomerase (DNA gyrase and topoisomerase IV).

    价 格：￥电议型 号：T71459产 地：中国大陆

  • T71391BRL 37344；化合物 BRL 37344BRL 37344

    BRL 37344 is a beta 3-adrenoceptor agonist.

    价 格：￥电议型 号：T71391产 地：中国大陆

  • T71344G-479；化合物 G-479G-479

    G-479 is an potent MEK inhibitor. Structurally, G-479 is an analogue of GDC-0623 (or so-call Me-Too drug). G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.

    价 格：￥电议型 号：T71344产 地：中国大陆

  • T70632DFL23448；化合物 DFL23448DFL23448

    DFL23448 is a TRPM8-selective ion channel antagonist, modifying bladder function and reduces bladder overactivity in awake rats.

    价 格：￥电议型 号：T70632产 地：中国大陆

  • T70344BJ-2302；化合物 BJ-2302BJ-2302

    BJ-2302 is a SRC inhibitor. BJ-2302 effectively suppressed MDA-MB-231 cell invasion (Matrigel invasion assay) and metastasis (chorioallantoic membrane assay xenografted with MDA-MB-231-luc2-tdTomato cancer cells). Additionally, BJ-2302 (1 mg/kg) strongly suppressed TNBC cell proliferation in vitro and tumor growth in a xenograft mouse tumor model. The anti-metastatic and anti-tumor effects of BJ-2302 were superior to those of Z-FL-COCHO (1 mg/kg) or batimastat (30 mg/kg), a pan-MMP inhibitor.

    价 格：￥电议型 号：T70344产 地：中国大陆

  • T69344Mimosinamine；化合物 MimosinamineMimosinamine

    Mimosinamine is an inhibitor of amino acid (Phe, Tyr, Trp) hydroxylases.

    价 格：￥电议型 号：T69344产 地：中国大陆

  • T68768EMD-23448；化合物 EMD-23448EMD-23448

    EMD-23448 is a dopamine autoreceptor agonist as potential antipsychotics.

    价 格：￥电议型 号：T68768产 地：中国大陆

  • T68344AGG-523；化合物 AGG-523AGG-523

    AGG-523 is an aggrecanase specific inhibitor that has been shown to attenuate increases in synovial fluid ARG-aggrecan levels following surgically-induced joint instability in the rat MT model. Pharmacologic inhibition of aggrecanase activity in humans using AGG-523 may be an effective treatment for slowing cartilage degradation following joint injury.

    价 格：￥电议型 号：T68344产 地：中国大陆

  • T68334AF3442；化合物 AF3442AF3442

    AF3442 is a potent and selective mPGES-1 inhibitor (microsomal prostaglandin (PG) E synthase-1). AF3442 caused a concentration-dependent inhibition of PGE(2) in human recombinant mPGES-1 with an IC(50) of 0.06microM. AF3442 is a selective mPGES-1 inhibitor which reduced monocyte PGE(2) generation also in the presence of plasma proteins. Pharmacological inhibition of mPGES-1 did not translate into redirection of PGH(2) metabolism towards other terminal PG synthases in monocytes. The functional re

    价 格：￥电议型 号：T68334产 地：中国大陆

  • T68103LMk-6186 HCl；Mk-6186盐酸盐Mk-6186 HCl（1034474-19-5 Free base)；Mk-6186 HCl（1034474-19-5 Free base)

    MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.

    价 格：￥电议型 号：T68103L产 地：中国大陆

  • T673443-Hydroxyisobenzofuran-1(3H)-one；化合物 3-Hydroxyisobenzofuran-1(3H)-one3-Hydroxyisobenzofuran-1(3H)-on

    3-Hydroxyisobenzofuran-1(3H)-one is a useful organic compound for research related to life sciences. The catalog number is T67344 and the CAS number is 16859-59-9.

    价 格：￥电议型 号：T67344产 地：中国大陆

  • T66344(2S,5R,6S)-Benzhydryl 6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-o

    (2S,5R,6S)-Benzhydryl 6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide is a useful organic compound for research related to life sciences. The catalog number is T66344 and the CAS number is 80353-26-0.

    价 格：￥电议型 号：T66344产 地：中国大陆

  • T65344N-(4-Cyano-3-(trifluoromethyl)phenyl)methacrylamide；化合物 N-(4-Cyano-3-(trifluoromethyl)phenyl)methacr

    N-(4-Cyano-3-(trifluoromethyl)phenyl)methacrylamide is a useful organic compound for research related to life sciences. The catalog number is T65344 and the CAS number is 90357-53-2.

    价 格：￥电议型 号：T65344产 地：中国大陆

  • T64344N-Methyl-DL-aspartic acid；N-甲基-DL-天冬氨酸N-Methyl-DL-aspartic acid

    N-Methyl-DL-aspartic acid, a glutamate analogue and NMDA receptor agonist, is utilized in neurological disease research.

    价 格：￥电议型 号：T64344产 地：中国大陆

  • T63449MsbA-IN-3；化合物 MsbA-IN-3MsbA-IN-3

    MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).

    价 格：￥电议型 号：T63449产 地：中国大陆

  • T63448BRAF V600E/CRAF-IN-1；化合物 BRAF V600E/CRAF-IN-1BRAF V600E/CRAF-IN-1

    BRAF V600E/CRAF-IN-1 is a potent inhibitor of BRAFV600E/CRAF. BRAF V600E/CRAF-IN-1 acts in the G0/G1 phase of HCT-116 colon cancer cells to arrest the cell cycle and cause apoptosis. BRAF V600E/CRAF-IN-1 shows potential for cancer disease research.

    价 格：￥电议型 号：T63448产 地：中国大陆

  • T63447FTO-IN-1 TFA；化合物 FTO-IN-1 TFAFTO-IN-1 TFA

    FTO-IN-1 TFA is an inhibitor of adiposity and obesity-related enzymes (FTO) (IC50 < 1 μM).FTO-IN-1 TFA can be used to study cancer.

    价 格：￥电议型 号：T63447产 地：中国大陆

  • T63446PKRA83；化合物 PKRA83PKRA83

    PKRA83 is a potent prokineticin (PK2) antagonist that crosses the blood-brain barrier and competes for PK2 binding to its receptors PKR1 and PKR2. PKRA83 effectively inhibits PK2 receptors and acts on PKR1 (IC50: 5.0 nM) and PKR2 (IC50: 8.2 nM). PKRA83 exhibits anti-cancer and anti-angiogenic effects.

    价 格：￥电议型 号：T63446产 地：中国大陆

  • T63445Amlodipine mesylate；化合物 Amlodipine mesylateAmlodipine mesylate

    Amlodipine mesylate is an oral active dihydropyridine calcium channel blocker that blocks voltage-dependent L-type calcium channels and inhibits calcium inward flow, and is an anti-anginal agent. amlodipine mesylate can be used to study hypertension and cancer.

    价 格：￥电议型 号：T63445产 地：中国大陆

  • T63444UNC4203；化合物 UNC4203UNC4203

    UNC4203 is a potent, highly selective, orally active MERTK inhibitor that acts on MERTK (IC50: 1.2 nM), AXL (IC50: 140 nM), TYRO3 (IC50: 42 nM) and FLT3 (IC50: 90 nM).

    价 格：￥电议型 号：T63444产 地：中国大陆

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