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T73840VU0453379 hydrochloride;化合物 VU0453379 hydrochlorideVU0453379 hydrochloride
VU0453379 hydrochloride is a central nervous system (CNS) penetrant and highly selective positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R), demonstrating efficacy with an EC50 of 1.3 μM [1].
价 格:¥电议型 号:T73840产 地:中国大陆
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T73453MRS4719;化合物 MRS4719MRS4719
MRS4719, a potent P2X4 receptor antagonist, exhibits a half-maximal inhibitory concentration (IC50) of 0.503 μM for the human P2X4 receptor. Demonstrating both neuroprotective and neuro-rehabilitative effects, it can decrease infarct volume and brain atrophy in an ischemic stroke model. Additionally, MRS4719 mitigates ATP-induced calcium influx in primary human monocyte-derived macrophages, making it a valuable tool for researching ischemic stroke.
价 格:¥电议型 号:T73453产 地:中国大陆
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T72453AChE/BChE/MAO-B-IN-3;化合物 AChE/BChE/MAO-B-IN-3AChE/BChE/MAO-B-IN-3
AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, serves as a potent inhibitor of human monoamine oxidase B (MAO-B) with an IC50 of 0.0359 μM, demonstrating significant inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 0.0473 μM and 0.0782 μM, respectively. Exhibiting notable antioxidant activity, AChE/BChE/MAO-B-IN-3 holds considerable promise for Alzheimer´s disease (AD) research.
价 格:¥电议型 号:T72453产 地:中国大陆
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T71527NSC145366;化合物 NSC145366NSC145366
NSC145366 is an inhibitor of Hsp90 activities which targets the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation. NSC145366 increases Hsp90 oligomerization resulting in allosteric inhibition of NTD ATPase activity (IC50=119μM) but does not compete with NTD or CTD-ATP binding.
价 格:¥电议型 号:T71527产 地:中国大陆
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T71453TriN2755;化合物 TriN2755TriN2755
TriN2755 is a synthetic triazene derivative with antineoplastic activity. Upon metabolic activation via N-demethylation, TriN2755 is converted into highly reactive carbocations that can alkylate DNA and other macromolecules, thereby resulting in DNA cross links, inhibiting DNA replication and repair, and subsequently inducing apoptosis. This agent has high hydrophilicity and photostability and shows a favorable toxicity profile over the other triazenes.
价 格:¥电议型 号:T71453产 地:中国大陆
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T6965RG7112;化合物RG7112RG-7112|||RG 7112|||RO5045337;RG-7112|||RG 7112|||RO5045337
RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.
价 格:¥电议型 号:T6965产 地:中国大陆
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T69611R-(+)-EU-1180-453;化合物 R-(+)-EU-1180-453R-(+)-EU-1180-453
R-(+)-EU-1180-453 is a useful organic compound for research related to life sciences. The catalog number is T69611 and the CAS number is 2488764-06-1.
价 格:¥电议型 号:T69611产 地:中国大陆
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T69453APC-0576;化合物 APC-0576APC-0576
APC-0576 is an (S,S)-isomer which inhibits NF-kappaB-dependent gene activation. APC-0576 may prevent pro-inflammatory cytokine-induced chemokine production in human endothelial cells.
价 格:¥电议型 号:T69453产 地:中国大陆
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T67972LAmp579 TFA;Amp579三氟乙酸盐Amp579 TFA(213453-89-5 Free base);Amp579 TFA(213453-89-5 Free base)
Amp579 TFA is a novel adenosine A1/A2a receptor agonist that induces acute and delayed preconditioning against myocardial shock in vivo.
价 格:¥电议型 号:T67972L产 地:中国大陆
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T674532-Phenyl-2-propanol;化合物 2-Phenyl-2-propanol2-Phenyl-2-propanol
2-Phenyl-2-propanol is a natural product for research related to life sciences. The catalog number is T67453 and the CAS number is 617-94-7.
价 格:¥电议型 号:T67453产 地:中国大陆
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T66453Fmoc PNA-G-(Bhoc)-OH;化合物 Fmoc PNA-G-(Bhoc)-OHFmoc PNA-G-(Bhoc)-OH
Fmoc PNA-G-(Bhoc)-OH is a useful organic compound for research related to life sciences and the catalog number is T66453.
价 格:¥电议型 号:T66453产 地:中国大陆
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T65453tert-Butyl diethylphosphonoacetate;化合物 tert-Butyl diethylphosphonoacetatetert-Butyl diethylphosphono
tert-Butyl diethylphosphonoacetate is a useful organic compound for research related to life sciences. The catalog number is T65453 and the CAS number is 27784-76-5.
价 格:¥电议型 号:T65453产 地:中国大陆
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T64539tert-Butyl 2-aminopropanoate hydrochloride;化合物 tert-Butyl 2-aminopropanoate hydrochloridetert-Butyl
tert-Butyl 2-aminopropanoate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64539 and the CAS number is 69320-88-3.
价 格:¥电议型 号:T64539产 地:中国大陆
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T645382-(4-Amino-1-oxoisoindolin-2-yl)pentanedioic acid;化合物 2-(4-Amino-1-oxoisoindolin-2-yl)pentanedioic a
2-(4-Amino-1-oxoisoindolin-2-yl)pentanedioic acid is a useful organic compound for research related to life sciences and the catalog number is T64538.
价 格:¥电议型 号:T64538产 地:中国大陆
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T64537Guanosine 5′-diphospho-β-L-fucose sodium salt;化合物 Guanosine 5′-diphospho-β-L-fucose sodium saltGuano
GDP-β-L-fucose is a metabolite in plant and animal. It used for microbe agglutination assay and agglutination inhibition assay. GDP-β-L-fucose is formed by the oxidation-reduction and epimerization of GDP-R-D-mannose in most organisms.
价 格:¥电议型 号:T64537产 地:中国大陆
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T64536Adamantane-1,3,5,7-tetraol;化合物 Adamantane-1,3,5,7-tetraolAdamantane-1,3,5,7-tetraol
Adamantane-1,3,5,7-tetraol is a useful organic compound for research related to life sciences and the catalog number is T64536.
价 格:¥电议型 号:T64536产 地:中国大陆
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T64535(R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride;化合物 (R)-N-(2,6-Dimethylphe
(R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64535.
价 格:¥电议型 号:T64535产 地:中国大陆
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T64533Ceramide (Egg, Chicken);神经酰胺(鸡蛋)Ceramide (Egg, Chicken)
Ceramide (Egg, Chicken) plays a major role in the anabolic and catabolic pathways of sphingolipid. Ceramide (Egg, Chicken) stimulates many cell differentiation, growth inhibition, cell senescence and apoptosis.
价 格:¥电议型 号:T64533产 地:中国大陆