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  • T80477Muscarinic toxin 3；化合物 Muscarinic toxin 3MT3；MT3

    Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57 for α1B, 8.13 for α1D, 8.49 for α2A, <6.5 for α2B, and 7.29 for α2C receptors. MT3 notably demonstrates significant adrenoceptor activity [1].

    价 格：￥电议型 号：T80477产 地：中国大陆

  • T79477SCAL-266；化合物 SCAL-266SCAL-266

    SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM. This compound impairs mitochondrial function by blocking oxidative phosphorylation (OXPHOS), inhibiting oxygen consumption rate (OCR), increasing reactive oxygen species (ROS) production, and diminishing mitochondrial membrane potential (MMP). Furthermore, SCAL-266 demonstrates significant antiproliferative activity against OXPHOS-dependent cancer cells [1].

    价 格：￥电议型 号：T79477产 地：中国大陆

  • T78477Drupanin；化合物 DrupaninDrupanin

    Drupanin, isolated from green propolis, selectively inhibits the AKR1C3 enzyme and shows promise for breast cancer research [1].

    价 格：￥电议型 号：T78477产 地：中国大陆

  • T77477Polatuzumab；维泊妥珠单抗Polatuzumab

    Polatuzumab is a monoclonal antibody that targets CD79b and carries chemotherapeutically active molecules.Polatuzumab adheres to CD79b proteins and transports the chemotherapeutically active molecules into cells to kill them.Polatuzumab can be used to synthesize the antibody-compound coupling, Polatuzumab Vedotin.

    价 格：￥电议型 号：T77477产 地：中国大陆

  • T7712LDisomotide TFA 181477-43-0(free base)；化合物Disomotide TFADisomotide TFA 181477-43-0(free base)

    Disomotide TFA is an oligopeptide for the treatment of melanoma.

    价 格：￥电议型 号：T7712L产 地：中国大陆

  • T77019Garetosmab加托索单抗REGN 2477

    Garetosmab (REGN 2477) is A whole-human IgG4 monoclonal antibody that selectively inhibits activin A and acts on COVID-19 44. Garetosmab has potential anti-cancer activity and can be used to study ossifying fibrous dysplasia (FOP) and cancer.

    价 格：￥电议型 号：T77019产 地：中国大陆

  • T76477[His11]Substance P；化合物 [His11]Substance P[His11]Substance P

    [His11]Substance P, an analog of Substance P (Substance P), functions as both a neurotransmitter and neuromodulator in the central nervous system (CNS) [1].

    价 格：￥电议型 号：T76477产 地：中国大陆

  • T75477Epicoccone B；化合物 Epicoccone BEpicoccone B

    Epicoccone B, originally identified in C. globosum, demonstrates both DPPH free radical scavenging capability, with an IC50 of 10.8 μM, and significant α-glucosidase inhibitory activity, with an IC50 of 27.3 μM. It also possesses anti-HIV activity [1] [2].

    价 格：￥电议型 号：T75477产 地：中国大陆

  • T74779JNJ-28583113；化合物 JNJ-28583113JNJ-28583113

    JNJ-28583113, a TRPM2 antagonist with brain permeability, inhibits the phosphorylation of GSK3α and β subunits, thereby protecting cells from oxidative stress-induced cell death. Additionally, it suppresses cytokine release in response to pro-inflammatory stimuli in microglia [1].

    价 格：￥电议型 号：T74779产 地：中国大陆

  • T74778ASM-IN-1；化合物 ASM-IN-1ASM-IN-1

    ASM-IN-1 is a potent, orally active inhibitor of acid sphingomyelinase (ASM) with an IC50 of 1.5 ?M, demonstrating antiatherosclerotic and anti-inflammatory activity. It effectively reduces lipid plaques in the aortic arch and aorta, along with decreasing plasma ceramide concentrations and oxidized LDL (Ox-LDL) levels [1].

    价 格：￥电议型 号：T74778产 地：中国大陆

  • T74777PLK1-IN-6；化合物 PLK1-IN-6PLK1-IN-6

    PLK1-IN-6, a potent and selective inhibitor of PLK1, demonstrates significant anti-proliferative activities against cancer cells with an IC50 value of 0.45 nM [1].

    价 格：￥电议型 号：T74777产 地：中国大陆

  • T74776Antibacterial agent 139；化合物 Antibacterial agent 139Antibacterial agent 139

    Antibacterial agent 139 exhibits antibacterial activity specifically targeting Gram-positive bacteria, including resistant strains such as MRSA (anti-MRSA), VISA (anti-VISA), and LRSE (anti-LRSE). It operates by depolarizing the bacterial cell membrane [1].

    价 格：￥电议型 号：T74776产 地：中国大陆

  • T74775Antibacterial agent 138；化合物 Antibacterial agent 138Antibacterial agent 138

    Antibacterial agent 138 exhibits superior efficacy against multi-drug resistant bacteria by inhibiting their protein synthesis and affecting bacterial cell walls [1].

    价 格：￥电议型 号：T74775产 地：中国大陆

  • T74774Neuraminidase-IN-16；化合物 Neuraminidase-IN-16Neuraminidase-IN-16

    Neuraminidase-IN-16 (Compound 43b) serves as a potent inhibitor of neuraminidase, demonstrating IC50 values of 0.031, 0.15, 0.25, 0.60, 0.63, and 10.08 μM against the neuraminidase from H5N1, H5N8, H1N1, H3N2, H5N1–H274Y, and H1N1–H274Y strains, respectively [1].

    价 格：￥电议型 号：T74774产 地：中国大陆

  • T74773Antiparasitic agent-14；化合物 Antiparasitic agent-14Antiparasitic agent-14

    Antiparasitic Agent-14 is a potent antiparasitic compound with demonstrated cytotoxicity and antiparasitic activity, effectively inhibiting the growth of trypomastigote and amastigote forms [1].

    价 格：￥电议型 号：T74773产 地：中国大陆

  • T74772Antifungal agent 47；化合物 Antifungal agent 47Antifungal agent 47

    Antifungal agent 47 (compound 3b) exhibits the most potent and broad-spectrum fungicidal properties, including significant inhibition of respiration and adenosine 5′-triphosphate synthesis, showcasing its potential as an effective fungicide [1].

    价 格：￥电议型 号：T74772产 地：中国大陆

  • T74771Diaporthein B；化合物 Diaporthein BDiaporthein B

    Diaporthein B, a highly oxidized pimarane diterpene, demonstrates significant activity against M. tuberculosis with a MIC of 3.1 μg/mL and exhibits IC50 values ranging from 1.5-3 μM/L against HCT 116 and LoVo colon cancer cells [1].

    价 格：￥电议型 号：T74771产 地：中国大陆

  • T74770D-685；化合物 D-685D-685

    D-685, a prodrug of D-520, demonstrates enhanced anti-Parkinsonian efficacy in a reserpinized Parkinson´s disease (PD) animal model compared to its parent compound D-520. It effectively reduces the buildup of human α-synuclein (α-syn) protein and readily penetrates the brain [1].

    价 格：￥电议型 号：T74770产 地：中国大陆

  • T7477Antazoline；安他唑啉Antazoline

    Antazoline has antihistamine and anticholinergic effects.It used to treat a variety of arrhythmias.

    价 格：￥电议型 号：T7477产 地：中国大陆

  • T74477m7GpppGmpG ammonium；化合物 m7GpppGmpG ammoniumm7GpppGmpG ammonium

    M7GpppGmpG ammonium, a trinucleotide 5′ cap analog, exhibits an 86% capping efficiency for the produced RNAs [1].

    价 格：￥电议型 号：T74477产 地：中国大陆

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