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T76559Survodutide;化合物SurvodutideBI 456906;BI 456906
Survodutide (BI 456906) is a dual agonist of glucagon and glucagon-like peptide 1 (GLP-1) receptor (GLP Receptor) that reduces body weight in HbA1c16 diabetes.
价 格:¥电议型 号:T76559产 地:中国大陆
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T76514HCV-1 e2 Protein (554-569);化合物 HCV-1 e2 Protein (554-569)HCV-1 e2 Protein (554-569)
HCV-1 e2 Protein (554-569), a primary antigenic region within the Hepatitis C Virus envelope 2 (e2) protein, features a putative N-glycosylation site believed to impact the immune recognition of e2 [1].
价 格:¥电议型 号:T76514产 地:中国大陆
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T7569LClebopride;化合物 T7569LClebopride
Clebopride is antidopaminergic. Clebopride also has an effect of antiemetic.
价 格:¥电议型 号:T7569L产 地:中国大陆
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T75699Coenzyme Q6;化合物 Coenzyme Q6Coenzyme Q6
Coenzyme Q6 (Ubiquinone 30), an isoprenylated benzoquinone lipid, plays a pivotal role in respiratory electron transport and acts as a lipid antioxidant. Besides, it possesses antioxidant properties that inhibit the generation of free radicals and prevent oxidative damage [1].
价 格:¥电议型 号:T75699产 地:中国大陆
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T75698Xylopine;化合物 XylopineXylopine
Xylopine, an aporphine alkaloid, exhibits cytotoxic effects on cancer cells by inducing oxidative stress, provoking G2/M cell cycle arrest, and triggering apoptosis [1].
价 格:¥电议型 号:T75698产 地:中国大陆
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T756971-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone;化合物 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(
1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, exhibits IC50 values of 20.1 μM and 34.1 μM, respectively. Additionally, it demonstrates significant anti-Helicobacter pylori activity, boasting a minimum inhibitory concentration (MIC) of 10 μg/mL [1] [2] [3].
价 格:¥电议型 号:T75697产 地:中国大陆
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T75696Ilexoside XLVIII;化合物 Ilexoside XLVIIIIlexoside XLVIII
Ilexoside XLVIII, a triterpene saponin isolated from the aqueous extract of Ilex kudincha leaves [1], functions as an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor.
价 格:¥电议型 号:T75696产 地:中国大陆
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T75695H-Asn(glcnac-beta-D)-OH;化合物 H-Asn(glcnac-beta-D)-OHH-Asn(glcnac-beta-D)-OH
H-Asn(glcnac-beta-D)-OH is an endogenous metabolite found in urine, utilized in the research of NGLY1-CDDG [1] [2].
价 格:¥电议型 号:T75695产 地:中国大陆
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T75694Lacto-N-neotetraose;化合物 Lacto-N-neotetraoseLacto-N-neotetraose
Lacto-N-neotetraose (LNnT), an endogenous metabolite, inhibits TNF-α-induced IL-8 secretion in immature epithelial cells, exhibits anti-inflammatory activity, and enhances wound closure [1] [2] [4].
价 格:¥电议型 号:T75694产 地:中国大陆
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T75693Crocin IV;化合物 Crocin IVCrocin IV
Crocin IV (Dicrocin), a crocetin glycoside belonging to the carotenoid pigments, exhibits significant antioxidant activity [1].
价 格:¥电议型 号:T75693产 地:中国大陆
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T75692Hypoglaunine D;化合物 Hypoglaunine DHypoglaunine D
Hypoglaunine D, an analogue of Triptonine B, serves as an anti-HIV compound by inhibiting HIV replication in H9 lymphocytes, demonstrating an efficacy with an EC50 value of 22 μg/ml [1].
价 格:¥电议型 号:T75692产 地:中国大陆
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T75691Amaroswerin;化合物 AmaroswerinAmaroswerin
Amaroswerin, a bioactive secoiridoid glucoside derived from Swertia mussotii, exhibits anti-inflammatory, antidiabetic, antiviral, anticholinergic, and immunomodulatory properties. It notably inhibits nitric oxide (NO) release in RAW264.7 cells with an IC50 value of 5.42 μg/mL [1].
价 格:¥电议型 号:T75691产 地:中国大陆
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T75690Wistin;化合物 WistinWistin
Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist [1] [2] .
价 格:¥电议型 号:T75690产 地:中国大陆
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T7569Clebopride malate苹果酸氯波必利苹果酸氯波必利|||氯波必利
Clebopride malate is a dopamine antagonist drug Used to treat functional gastrointestinal disorders such as nausea or vomiting.
价 格:¥电议型 号:T7569产 地:中国大陆
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T75569Xerophilusin B;化合物 Xerophilusin BXerophilusin B
Xerophilusin B, isolated from Isodon xerophilus as an anticancer agent, demonstrates antiproliferative effects on esophageal squamous cell carcinoma (ESCC) cell lines. It induces G2/M cell cycle arrest and mediates apoptosis [1].
价 格:¥电议型 号:T75569产 地:中国大陆
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T74569Bepirovirsen;化合物 BepirovirsenBepirovirsen
Bepirovirsen, an antisense oligonucleotide, targets all HBV messenger RNAs, resulting in decreased levels of HBV-derived RNAs, HBV DNA, and viral proteins. It is utilized in researching chronic HBV infection. The binding site sequence of Bepirovirsen is (GCACTTCGCTTCACCTCTGC) [1].
价 格:¥电议型 号:T74569产 地:中国大陆
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T7295Miridesap;化合物MiridesapRo63-8695|||CPHPC|||GSK2315698;Ro63-8695|||CPHPC|||GSK2315698
Miridesap (GSK2315698) is a divalent crosslinker of SAP that causes rapid depletion of circulating SAP via hepatic clearance. It also produces significant reduction of SAP from cerebrospinal fluid and visceral amyloid deposits
价 格:¥电议型 号:T7295产 地:中国大陆
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T72569Cathepsin L/S-IN-1;化合物 Cathepsin L/S-IN-1Cathepsin L/S-IN-1
Cathepsin L/S-IN-1, a dual inhibitor targeting Cathepsin L and Cathepsin S, exhibits potent and selective inhibition with IC50 values of 4.10 μM and 1.79 μM, respectively. Demonstrating significant antimetastatic and invasive effects, it effectively impacts pancreatic cancer BxPC-3 and PANC-1 cells.
价 格:¥电议型 号:T72569产 地:中国大陆
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T71971CS-0045569;化合物 CS-0045569CS-0045569
CS-0045569, also known ZUN24972, is an important chemical intermediate for drug synthesis. It was reported in WO 2020086857 (compound 27, page 57) as an intermediate for synthesis of WDR5 inhibitor.
价 格:¥电议型 号:T71971产 地:中国大陆