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  • T4569Lucanthone；硫蒽酮Lucantona|||Lucanthonum；Lucantona|||Lucanthonum|||硫坎酮|||硫蒽酮

    Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).

    价 格：￥电议型 号：T4569产 地：中国大陆

  • T41121Elubrixin tosylate；Elubrixin tosylateSB-656933 tosylate|||Elubrixin tosylate；SB-656933 tosylate|||El

    Elubrixin tosylate (SB-656933 tosylate) is a high-potency, selective, competitive, and reversible CXCR2 antagonist, as well as an antagonist of the IL-8 receptor. It effectively inhibits upregulation of neutrophil CD11b (with an IC50 of 260.7 nM) and shape change (with an IC50 of 310.5 nM). This compound holds promise for the study of inflammatory diseases, including inflammatory bowel disease and airway inflammation.

    价 格：￥电议型 号：T41121产 地：中国大陆

  • T40569Hygric acid；古液酸N-Methyl-L-proline；N-Methyl-L-proline|||古液酸；古柯叶液碱酸

    Hygric acid (N-Methyl-L-proline) (N-Methyl-L-proline) is a proline analogue found in the citrus juices and the bergamot juice.

    价 格：￥电议型 号：T40569产 地：中国大陆

  • T39955JNJ-67569762；JNJ-67569762JNJ-67569762

    JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).

    价 格：￥电议型 号：T39955产 地：中国大陆

  • T39569Gp100 (25-33), mouse；Gp100 (25-33), mouseMgp100 (25-33)|||Gp100 (25-33), mouse；Mgp100 (25-33)|||Gp10

    Gp100 (25-33) corresponds to residues 25 to 33 of the mouse self/tumor antigen glycoprotein (mgp100), which is an enzyme responsible for pigment synthesis. This epitope fragment is found in both normal melanocytes and melanoma cells.

    价 格：￥电议型 号：T39569产 地：中国大陆

  • T38569Tos-PEG2-OH；Tos-PEG2-OHTos-PEG2-OH；Tos-PEG2-OH

    Tos-PEG2-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T38569产 地：中国大陆

  • T375694-Methylumbelliferyl-β-D-Galactoside；4-Methylumbelliferyl-β-D-Galactoside4-Methylumbelliferyl-β-D-Ga

    4-Methylumbelliferyl-β-D-galactoside (MUG) is a fluorogenic substrate for β-galactosidase (β-gal).1Hydrolysis of MUG by β-gal releases the fluorescent moiety 4-MU, which displays a pH-dependent excitation maximum of 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively, and an emission maximum between 445-454 nm.2MUG has been used to detect β-gal activity in intact bacteria, yeast, and mammalian cells.1

    价 格：￥电议型 号：T37569产 地：中国大陆

  • T37294GoSlo-SR-5-69GoSlo SR 5-69GoSlo-SR-5-69|||GoSloSR569|||GoSlo SR 5 69

    BK channel activator (EC50 = 251 nM). Shifts the voltage required for half maximal negatively (DV1/2 = -104 mV).

    价 格：￥电议型 号：T37294产 地：中国大陆

  • T36569KR-32568；化合物KR-32568KR-32568

    KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM). KR-32568 exhibits potent cardioprotective effects. When used at a concentration of 10 μM, it restored cardiac systolic function in an isolated ischemic rat heart model. KR-32568 (0.3 mg/kg) reduced the size of myocardial infarction in a rat model of ischemia and reperfusion injury.

    价 格：￥电议型 号：T36569产 地：中国大陆

  • T35699Fosetyl-aluminum；Fosetyl-aluminumFosetyl-aluminum

    0$r$n[1]. Fan Z, Jia S, Ding N, et al. Determination of Fosetyl-Aluminium by Ion-Pair Reversed Phase-High Performance Liquid Chromatography With Evaporative Light Scattering Detection. Se Pu. 2009;27(6):849‐851. [2]. TüRK LMEZ , et al. Activity of metalaxyl-M+mancozeb, fosetyl-Al, and phosphorous acid against Phytophthora crown and root rot of apricot and cherry caused by Phytophthora palmivora. Plant Protect. Sci., 53: 216-225.

    价 格：￥电议型 号：T35699产 地：中国大陆

  • T35698Octanoic Acid-13C；Octanoic Acid-13COctanoic Acid-13C

    Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d

    价 格：￥电议型 号：T35698产 地：中国大陆

  • T35697Lauric Acid-13CLauric Acid-13CLauric Acid 13C|||Lauric Acid13C

    Lauric acid-13C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil.1Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.2

    价 格：￥电议型 号：T35697产 地：中国大陆

  • T35696Olomoucine IIOlomoucine IIOlomoucine II

    Olomoucine II is an inhibitor of cyclin-dependent kinases (CDKs; IC50s = 7.6, 0.1, 19.8, 0.45, and 0.06 μM for Cdk1, -2, -4, -7, and -9, respectively).1It is selective for CDKs over 10 additional kinases (IC50s = >100 μM for all) but does inhibit ERK2 (IC50= 32 μM) and the ATP-binding cassette transporter B1 (ABCB1; IC50= 6.4 μM).1,2Olomoucine II inhibits proliferation of a variety of cancer cells, including those expressing wild-type p53 or mutant p53 (mean IC50s = 7.4 and 10.1 μM, respectively

    价 格：￥电议型 号：T35696产 地：中国大陆

  • T35695Oleic Acid-13C；Oleic Acid-13COleic Acid-13C

    Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.1,2 It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximate

    价 格：￥电议型 号：T35695产 地：中国大陆

  • T35694OD36；化合物OD36OD 36|||OD 36 hydrochloride|||OD-36；OD 36|||OD 36 hydrochloride|||OD-36

    OD36 is a selective and potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 inhibits ALK2 signaling and osteogenic differentiation (KD: 37 nM), and binds efficiently to the ALK2 kinase ATP pocket.

    价 格：￥电议型 号：T35694产 地：中国大陆

  • T35693N-(2-Azidoethyl)betulonamide；N-(2-Azidoethyl)betulonamideN-(2-Azidoethyl)betulonamide

    N-(2-Azidoethyl)betulonamide is a pentacyclic triterpenoid, a derivative of betulonic acid , and an intermediate in the synthesis of betulonic acid derivatives within vitrocancer cell cytotoxicity.1

    价 格：￥电议型 号：T35693产 地：中国大陆

  • T35692Myxochelin A；Myxochelin AMyxochelin A

    Myxochelin A is a microbial metabolite that has been found inA. disciformisand has diverse biological activities.1It is active against Gram-positive bacteria, includingB. cereus,S. aureus, andM. luteus, but not Gram-negative bacteria or fungi in an agar diffusion assay when used at a concentration of 80 μg/disc. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity with an IC50value of 1.9 μM for the recombinant human enzyme.2It is cytotoxic to 26-L5 colon cancer cells when used at a concentratio

    价 格：￥电议型 号：T35692产 地：中国大陆

  • T35691Myristoyl Coenzyme A (hydrate)；Myristoyl Coenzyme A (hydrate)Myristoyl Coenzyme A (hydrate)

    Myristoyl coenzyme A (myristoyl-CoA) is a derivative of CoA that contains the long-chain fatty acid myristic acid . It is a substrate for N-myristoyltransferase during myristoylation, a process that adds a myristoyl group to proteins either during translation to modify protein activity or post-translationally in apoptotic cells. It is also a substrate in the de novo synthesis of phosphatidylinositol .

    价 格：￥电议型 号：T35691产 地：中国大陆

  • T35690Myceliothermophin E；Myceliothermophin EMyceliothermophin E

    Myceliothermophin E is a polyketide-amino acid hybrid fungal metabolite that has been found inT. thermophilusand has anticancer and antimicrobial activities.1,2It is cytotoxic to DLD-1, Hep3B, HepG2, and HGC-27 cancer cells (IC50s = 0.32, 0.42, 0.26, and 0.08 μg/ml, respectively).1Myceliothermophin E is active against methicillin-resistant, but not -sensitive,S. aureus(MICs = 15.8 and >100 μM, respectively).2

    价 格：￥电议型 号：T35690产 地：中国大陆

  • T3569SU5214；化合物SU 5214SU 5214；SU 5214

    SU5214 is a modulator of tyrosine kinase signal transduction.

    价 格：￥电议型 号：T3569产 地：中国大陆

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