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  • T75948K-(D-1-Nal)-FwLL-NH2 TFA；化合物 K-(D-1-Nal)-FwLL-NH2 TFAK-(D-1-Nal)-FwLL-NH2 TFA

    K-(D-1-Nal)-FwLL-NH2 TFA is a potent and high-affinity inverse agonist of the ghrelin receptor, exhibiting Ki values of 4.9 nM in COS7 cells and 31 nM in HEK293T cells. This compound effectively inhibits ghrelin receptor-mediated Gq- and G13-dependent signaling pathways.

    价 格：￥电议型 号：T75948产 地：中国大陆

  • T75947RFRP-1(human) TFA；化合物 RFRP-1(human) TFARFRP-1(human) TFA

    RFRP-1(human) TFA, an endogenous NPFF receptor agonist, exhibits potent activity with EC50 values of 0.0011 nM for NPFF2 and 29 nM for NPFF1. It significantly diminishes the contractile function of isolated rat and rabbit cardiac myocytes. Moreover, it decreases heart rate, stroke volume, ejection fraction, and cardiac output, while elevating plasma prolactin levels in rats.

    价 格：￥电议型 号：T75947产 地：中国大陆

  • T75946Lei-Dab7 TFA；化合物 Lei-Dab7 TFALei-Dab7 TFA

    Lei-Dab7 TFA, a selective and high-affinity blocker of the K Ca 2.2 (SK2) channel with a dissociation constant (K d) of 3.8 nM, demonstrates over 200-fold selectivity for K Ca 2.2 compared to K Ca 2.1, K Ca 2.3, K Ca 3.1, K v, and Kir2.1. Furthermore, Lei-Dab7 TFA enhances theta-burst responses and long-term potentiation (LTP) in rat hippocampal slices in vitro.

    价 格：￥电议型 号：T75946产 地：中国大陆

  • T75945BA 1 TFA；化合物 BA 1 TFABA 1 TFA

    BA 1 TFA acts as a potent agonist for the bombesin (BB) family of receptors, exhibiting high affinity binding to Bombesin receptor subtype-3 (BRS3), gastrin-releasing peptide receptor (GRPR), and neuromedin B receptor (NMBR), with IC50 values of 6, 0.4, and 2.5 nM, respectively [1].

    价 格：￥电议型 号：T75945产 地：中国大陆

  • T75944Spadin TFA；化合物 Spadin TFASpadin TFA

    Spadin TFA, a natural peptide originating from a propeptide in blood, acts as a powerful TREK-1 channel inhibitor with an IC 50 of 10 nM. It boosts dorsal raphe nucleus 5-HT neurotransmission in mice, activates hippocampal CREB, and promotes neurogenesis. This compound is useful for antidepressant research [1] [2].

    价 格：￥电议型 号：T75944产 地：中国大陆

  • T75943TAT-cyclo-CLLFVY TFA；化合物 TAT-cyclo-CLLFVY TFATAT-cyclo-CLLFVY TFA

    TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor specifically targeting HIF-1 heterodimerization to mitigate hypoxia signaling within cancer cells. It effectively disrupts the protein-protein interaction between HIF-1α and HIF-1β, demonstrating an inhibitory concentration (IC 50) of 1.3 μM [1].

    价 格：￥电议型 号：T75943产 地：中国大陆

  • T75942DPC-AJ1951 TFA；化合物 DPC-AJ1951 TFADPC-AJ1951 TFA

    DPC-AJ1951 TFA, a 14-amino acid peptide, functions as a potent agonist for the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). It has been characterized for its activity through ex vivo and in vivo bone resorption assays [1].

    价 格：￥电议型 号：T75942产 地：中国大陆

  • T75941Foxy-5 TFA；化合物 Foxy-5 TFAFoxy-5 TFA

    Foxy-5 TFA, a WNT5A agonist and mimicking peptide of WNT5A (a non-canonical Wnt family member), induces cytosolic free calcium signaling without altering β-catenin activation. This compound inhibits the migration and invasion of epithelial cancer cells and significantly diminishes the metastatic progression of WNT5A-low prostate cancer cells in an orthotopic mouse model [1] [2] [3] [4].

    价 格：￥电议型 号：T75941产 地：中国大陆

  • T75940Norleual TFA；化合物 Norleual TFANorleual TFA

    Norleual TFA, an analog of angiotensin (Ang) IV, functions as a hepatocyte growth factor (HGF)/c-Met inhibitor, displaying a potent inhibition capability with an IC50 of 3 pM. Additionally, it acts as an AT4 receptor antagonist and demonstrates significant antiangiogenic activities [1].

    价 格：￥电议型 号：T75940产 地：中国大陆

  • T7594Vinflunine长春氟宁Vinflunine

    Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.

    价 格：￥电议型 号：T7594产 地：中国大陆

  • T75594Harpactira Baviana Venom；化合物 Harpactira Baviana VenomHarpactira Baviana Venom

    Harpactira Baviana Venom (Baboon Tarantula Venom), derived from the king baboon spider, modulates Na V 1.8 and induces hyperalgesia [1] [2].

    价 格：￥电议型 号：T75594产 地：中国大陆

  • T74594Tonlamarsen；化合物 TonlamarsenTonlamarsen

    Tonlamarsen is a angiotensinogen synthesis reducer, with antihypertensive activity [1] .

    价 格：￥电议型 号：T74594产 地：中国大陆

  • T7418BBT594；化合物BBT594NVP-BBT594；NVP-BBT594

    BBT594 (NVP-BBT594)(NVP-BBT594) is a potent inhibitor of receptor tyrosine kinase RET,Treatment of cancer.

    价 格：￥电议型 号：T7418产 地：中国大陆

  • T73594Chymotrypsin；胰凝乳蛋白酶Chymotrypsin A；Chymotrypsin A

    Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas that cleaves protein chains on the carboxyl side of aromatic amino acids.

    价 格：￥电议型 号：T73594产 地：中国大陆

  • T72999PF-06455943；化合物 PF-06455943PF-06455943

    PF-06455943, a leucine rich repeat kinase 2 (LRRK2) inhibitor, exhibits an inhibition concentration (IC50) value of 3 nM and also functions as a PET radioligand. It is utilized in the research of ADME/neuro PK characterization and Parkinson´s disease (PD).

    价 格：￥电议型 号：T72999产 地：中国大陆

  • T72982DPNB-ABT594；化合物 DPNB-ABT594DPNB-ABT594

    DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates nAChRs containing α4β2 subunits over the α7 subunit. It is utilized to map the distribution of nAChRs on medial habenula (MHb) neurons, thereby facilitating a deeper understanding of nAChR-mediated Ca2+ signaling in the MHb [1].

    价 格：￥电议型 号：T72982产 地：中国大陆

  • T7280CAY10594；化合物CAY10594CAY10594

    CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.

    价 格：￥电议型 号：T7280产 地：中国大陆

  • T72594Broussochalcone A；化合物 Broussochalcone ABroussochalcone A

    Broussochalcone A, an antioxidant and Xanthine Oxidase inhibitor (IC 50 =2.21 μM), exhibits free radical scavenging activity. It prevents iron-induced lipid peroxidation and nitric oxide synthesis in lipopolysaccharide (LPS)-activated macrophages. Additionally, Broussochalcone A triggers apoptosis in human renal carcinoma cells by elevating ROS levels and activating FOXO3 signaling pathways.

    价 格：￥电议型 号：T72594产 地：中国大陆

  • T7221Satraplatin；沙铂BMS182751|||JM216|||BMY45594；BMS182751|||JM216|||顺式-二氯-反式-二乙酸-氨-环己胺合铂|||BMY45594

    Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malignancies.

    价 格：￥电议型 号：T7221产 地：中国大陆

  • T71594SC 42867；化合物 SC 42867SC 42867

    SC 42867 is a PGE2 antagonist.

    价 格：￥电议型 号：T71594产 地：中国大陆

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