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  • T37594Pericosine A；Pericosine APericosine A

    Pericosine A is a fungal metabolite that has been found inP. byssoidesand has anticancer activity.1It inhibits the growth of a variety of cancer cells, including breast, colon, lung, ovary, stomach, and prostate cell lines (GI50s = 0.05-24.55 μM) and increases survival in a P388 mouse xenograft model when administered at a dose of 25 mg/kg. Pericosine A inhibits EGFR by 40 to 70% when used at a concentration of 100 μg/ml. It also reacts with organosulfur compounds in skunk spray to form stable t

    价 格：￥电议型 号：T37594产 地：中国大陆

  • T3720Tebanicline hydrochloride；替巴克兰盐酸盐ABT-594 hydrochloride|||Ebanicline hydrochloride；替巴克兰盐酸盐|||ABT-594

    Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.

    价 格：￥电议型 号：T3720产 地：中国大陆

  • T365944-Chloroguaiacol；4-Chloroguaiacol4-Chloroguaiacol

    4-Chloroguaiaco (4-Chloro-2-methoxyphenol), a derivative of phenol, demonstrates antimicrobial efficacy, inhibiting Staphylococcus aureus and Escherichia coli with minimum inhibitory concentrations (MICs) of 110 μg/mL for both pathogens [1].

    价 格：￥电议型 号：T36594产 地：中国大陆

  • T359494-Carboxypyrazole；4-Carboxypyrazole4-Carboxypyrazole

    4-Carboxypyrazole is an endogenous metabolite.

    价 格：￥电议型 号：T35949产 地：中国大陆

  • T359484-carboxy TEMPO；4-carboxy TEMPO4-carboxy TEMPO

    4-carboxy TEMPO is a nitroxide and spin label. Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo., It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.

    价 格：￥电议型 号：T35948产 地：中国大陆

  • T3594717(S)-HDHA；17(S)-HDHA17(S)-HDHA

    17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain. 17(S)-HDHA serves as a precursor to 17(S)-resolvins and has intrinsic biological activity, such as the inhibition of TNF-α-induced interleukin-1β expression in human glioma cells and inhibition of TNF-α-induced leukocyte trafficking to the mouse air pouch.

    价 格：￥电议型 号：T35947产 地：中国大陆

  • T3594617(R)-Resolvin D1；17(R)-Resolvin D1Aspirin-triggered Resolvin D1|||17(R)-Resolvin D1；Aspirin-trigger

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.[1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.[2] Resolvin D1 is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase.[1] 17(R)-RvD1 is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte (PMN) transendothelial migration, the ear

    价 格：￥电议型 号：T35946产 地：中国大陆

  • T3594515-OxoETE；15-OxoETE15-OxoETE

    15-OxoETE is produced by oxidation of the 15-hydroxyl of 15-HETE. Whether this is a major pathway of 15-HETE metabolism is yet to be clearly established.

    价 格：￥电议型 号：T35945产 地：中国大陆

  • T3594415-keto-17-phenyl trinor Prostaglandin F2α ethyl amide；15-keto-17-phenyl trinor Prostaglandin F2α et

    Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacologi

    价 格：￥电议型 号：T35944产 地：中国大陆

  • T3594315(S)-HpETE；15(S)-HpETE15(S)-HpETE

    15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 [1] or reduced to 15(S)-HETE by peroxidases.[2] [1] 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1. [3] 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inac

    价 格：￥电议型 号：T35943产 地：中国大陆

  • T35942AZ 5704；AZ 5704AZ 5704

    Potent and selective ATM kinase inhibitor (IC50 = 0.6 nM in an enzyme inhibition assay). Exhibits > 600-fold selectivity for ATM over other kinases. Inhibits ATM kinase in an in vitro cellular assay (IC50 = 0.33 μM). Potentiates the antitumor effects of the topoisomerase 1 inhibitor irinotecan in tumor bearing, immunocompromised mice. Orally bioavailable.

    价 格：￥电议型 号：T35942产 地：中国大陆

  • T35941DC-Chol hydrochloride；DC-胆固醇盐酸盐?Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride|||DC-Ch

    DC-Chol hydrochloride(DC-Cholesterol hydrochloride) inhibited the formation of Aβ40 fibrils under appropriate experimental conditions and significantly inhibited amyloid formation from oxidized hCT in a dose-dependent manner.DC-Chol hydrochloride induces an improved and balanced immunity, which could contribute to hepatitis B vaccine research.

    价 格：￥电议型 号：T35941产 地：中国大陆

  • T3594ML346；化合物ML346ML346

    ML346 is a novel activator of Hsp70.

    价 格：￥电议型 号：T3594产 地：中国大陆

  • T35594Cuspin-1Cuspin-1Cuspin 1|||Cuspin1

    The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA). Cuspin-1 is a small molecule upregulator of SMN that has been shown in vitro to increase levels of SMN in SMA patient fibroblasts by 50% at 18 μM. Its mechanism of action is thought to involve increased phosphorylation of ERK to initiate Ras-Ra

    价 格：￥电议型 号：T35594产 地：中国大陆

  • T35187XR 5944；化合物 XR 5944XR5944|||MLN 944|||MLN-944|||XR-5944|||MLN944；XR5944|||MLN 944|||MLN-944|||XR-594

    XR 5944 is an antitumor compound that targets DNA, is a topoisomerase inhibitor, inhibits ER activity, and can be used to study colon and lung cancer.

    价 格：￥电议型 号：T35187产 地：中国大陆

  • T34905Totrombopag；化合物TotrombopagSB559448|||SB 559448|||SB-559448|||LGD-4665|||Synonym 2|||LGD 4665|||LGD46

    Totrombopag (SB559448) is a candidate compound for action on RSV polymerase.

    价 格：￥电议型 号：T34905产 地：中国大陆

  • T34594SDZ 282395；化合物 T34594SDZ282395|||SDZ-282395；SDZ282395|||SDZ-282395

    SDZ 282395 is a bioactive chemical.

    价 格：￥电议型 号：T34594产 地：中国大陆

  • T34359Ro 3-5940 HCl；化合物 T34359Ro 3 5940 HCl；Ro 3 5940 HCl

    Ro 3-5940 HCl is a psychoactive agent, increasing in production of serotonin in central nervous system tissue.

    价 格：￥电议型 号：T34359产 地：中国大陆

  • T33728Nothosymyrnol；化合物 T33728CCRIS 1594；CCRIS 1594

    Nothosymyrnol has a wide range of applications in life science related research.

    价 格：￥电议型 号：T33728产 地：中国大陆

  • T33594Napropamide-M；化合物 T33594(R)-Devrinol|||D-Napropamide；(R)-Devrinol|||D-Napropamide

    Napropamide-M is a herbicide.

    价 格：￥电议型 号：T33594产 地：中国大陆

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