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T73672CH-0793076 TFA；CH-0793076 TFACH-0793076 TFA
CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC 50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resistance protein) [1] .
价 格：￥电议型 号：T73672产 地：中国大陆
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T73459DS-9300；化合物 DS-9300DS-9300
DS-9300, an orally administered potent and selective inhibitor of EP300/CBP HAT, exhibits a significant inhibitory activity with an IC50 value of 28 nM. Demonstrating anticancer properties, it is utilized in research focused on prostate cancer disease.
价 格：￥电议型 号：T73459产 地：中国大陆
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T72930NCGC00138783；化合物 NCGC00138783NCGC00138783
NCGC00138783 is a selective inhibitor of the CD47/SIRPα axis, demonstrating its efficacy by directly blocking the interaction between CD47 and SIRPα, with an inhibitory concentration (IC 50) of 50 ?M.
价 格：￥电议型 号：T72930产 地：中国大陆
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T71930aPKC-I；化合物 aPKC-IaPKC-I
aPKC-I is an inhibitor of atypical protein kinase C (aPKC ) which inhibits both PKCζ and PKCι with high specificity and prevents VEGF-induced endothelial permeability in cell culture and in vivo, thereby blocking ischemia-reperfusion (IR)-induced permeability.
价 格：￥电议型 号：T71930产 地：中国大陆
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T70930GSK SYK inhibitor；化合物 GSK SYK inhibitorGSK SYK inhibitor
The immunoregulator spleen tyrosine kinase (SYK) is upregulated in cutaneous lupus erythematosus (CLE). This double-blind, multicentre, Phase Ib study evaluated the safety, tolerability, pharmacokinetics, pharmacodynamics and clinical efficacy of the selective SYK inhibitor GSK2646264 in active CLE lesions
价 格：￥电议型 号：T70930产 地：中国大陆
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T6S1930Schisanhenol；五味子酚Schizanhenol|||Gomisin-K3；五味子酚|||Schizanhenol|||Gomisin-K3
1. Schisanhenol (Schizanhenol) can protect against adriamycin induced heart mitochondrial toxicity. 2. Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals. 3. Schisanhenol has anti-apoptosis effect on BACSs, may be related to its inhibition of ROS generation.
价 格：￥电议型 号：T6S1930产 地：中国大陆
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T69930LEO 134310；化合物 LEO-134310LEO 134310
LEO 134310, a selective, non-steroidal glucocorticoid receptor (GR) agonist, is optimized for topical treatment. Demonstrating high affinity (EC50 of 14 nM) in GR binding assays, it is suitable for treating skin diseases.
价 格：￥电议型 号：T69930产 地：中国大陆
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T69308Spliceostatin A；司普利斯他汀ASpliceostatin A
Spliceostatin A is an anticancer agent and splicing inhibitor that inhibits the splicing mechanism of the spliceosome and inhibits mitotic clonal expansion and adipogenesis.Spliceostatin A induces cell cycle arrest in the G1 and G2/M phases, and induces apoptosis.
价 格：￥电议型 号：T69308产 地：中国大陆
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T69306Lubabegron fumarate；化合物 Lubabegron fumarateLubabegron fumarate
Lubabegron, also known as LY591281; LY488756 fumarate, is a veterinary drug used to reduce ammonia emissions from animals and their waste. Ammonia emissions are a concern in agricultural production because of detrimental effects on the environment, human health, and animal health. Lubabegron was approved by the U.S. Food and Drug Administration in 2018 for use in feedlot cattle. Lubabegron is a beta-adrenergic receptor agonist that has the effect of increasing the breakdown of fats and increasin
价 格：￥电议型 号：T69306产 地：中国大陆
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T69305Milataxel；化合物 MilataxelMilataxel
Milataxel is an orally bioavailable taxane with potential antineoplastic activity. Upon oral administration, milataxel and its major active metabolite M-10 bind to and stabilize tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, milataxel appears to be a poor substrate for the multidrug resistance (MDR) membrane-associated P-glycoprotein (P-gp)
价 格：￥电议型 号：T69305产 地：中国大陆
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T69304MRL20；化合物 MRL20MRL20
MRL20 is a selective PPARγ modulator (SPPARγM) which displays robust anti-diabetic activity with an improved therapeutic window in comparison to a PPARγ full agonist in a rodent efficacy model.
价 格：￥电议型 号：T69304产 地：中国大陆
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T69303Isoxsuprine Free Base；化合物 Isoxsuprine Free BaseIsoxsuprine Free Base
Isoxsuprine Free Base is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
价 格：￥电议型 号：T69303产 地：中国大陆
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T69302Cloranolol；化合物 CloranololCloranolol
Cloranolol is a long-acting beta-blocker.
价 格：￥电议型 号：T69302产 地：中国大陆
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T69301Picumast dihydrochloride；化合物 Picumast dihydrochloridePicumast dihydrochloride
Picumast dihydrochloride is a prophylactically active anti-allergic compound which combines inhibition of mediator release and action. The activity profile of PDH differs clearly from that of known prophylactic anti-allergic drugs such as DSCG and ketotifen.
价 格：￥电议型 号：T69301产 地：中国大陆
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T69300AVE-1330A free acid；化合物 AVE-1330A free acidAVE-1330A free acid
AVE-1330A free acid is a broad-spectrum non-beta-lactam beta-lactamase inhibitor.
价 格：￥电议型 号：T69300产 地：中国大陆
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T6930Pazopanib Hydrochloride；盐酸帕唑帕尼GW786034|||Pazopanib HCl|||GW786034 HCl|||Votrient HCl|||Armala；GW7860
Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
价 格：￥电议型 号：T6930产 地：中国大陆
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T68930Milveterol；化合物 MilveterolMilveterol
Milveterol is a long-acting β(2)-adrenoceptor agonist.
价 格：￥电议型 号：T68930产 地：中国大陆
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T67930LCWI1-2 HCL；CWI1-2盐酸盐CWI1-2 HCL
CWI1-2 HCL is an effective IGF2BP2 inhibitor, which can induce apoptosis and differentiation by binding IGF2BP2 and inhibiting its interaction with M6A-modified target transcription, and has therapeutic effects on leukemia.
价 格：￥电议型 号：T67930L产 地：中国大陆
