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T67930CWI1-2;化合物CWI1-2CWI1-2
CWI1-2 is a potent IGF2BP2 inhibitor that inhibits its interaction with M6A-modified target transcripts by binding IGF2BP2. CWI1-2 has anti-leukemic activity and can induce apoptosis and differentiation.
价 格:¥电议型 号:T67930产 地:中国大陆
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T66930H-D-Arg-OH.HCl;化合物 H-D-Arg-OH.HClH-D-Arg-OH.HCl
H-D-Arg-OH.HCl is an amino acid derivative and has a wide range of applications in life science related research.
价 格:¥电议型 号:T66930产 地:中国大陆
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T659302-Isobutyramidoacetic acid;化合物 2-Isobutyramidoacetic acid2-Isobutyramidoacetic acid
2-Isobutyramidoacetic acid is a useful organic compound for research related to life sciences. The catalog number is T65930 and the CAS number is 15926-18-8.
价 格:¥电议型 号:T65930产 地:中国大陆
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T64930(3,4-Dimethoxypyridin-2-yl)methanol;化合物 (3,4-Dimethoxypyridin-2-yl)methanol(3,4-Dimethoxypyridin-2-y
(3,4-Dimethoxypyridin-2-yl)methanol is a useful organic compound for research related to life sciences. The catalog number is T64930 and the CAS number is 72830-08-1.
价 格:¥电议型 号:T64930产 地:中国大陆
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T63930DI-1859;化合物 DI-1859DI-1859
DI-1859 is a selective, potent and covalent inhibitor of DCN1. At low nanomolar concentrations, DI-1859 inhibits the neddylation of cullin 3 in cells. DI-1859 induces a significant increase in NRF2 protein, a CRL3 substrate, in mouse liver and effectively protects mice from acetaminophen-induced liver injury.
价 格:¥电议型 号:T63930产 地:中国大陆
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T6303LCCT128930 hydrochloride;化合物CCT128930 hydrochlorideCCT128930 hydrochloride(885499-61-6 Free base);CCT
CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50: 168 nM) through the targeting of Met282 of AKT, as well as 20-fold selectivity over p70S6K (IC50: 120 nM).
价 格:¥电议型 号:T6303L产 地:中国大陆
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T6303CCT128930;化合物CCT128930CCT128930
CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.
价 格:¥电议型 号:T6303产 地:中国大陆
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T62930GT-055;化合物 GT-055GT-055
GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.
价 格:¥电议型 号:T62930产 地:中国大陆
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T61976DS-6930;化合物 DS-6930DS-6930
DS-6930 is an potent and selective PPAR γ Agonists with EC50 of 41 nM. DS-6930 can effectively reduce plasma glucose (PG) level, and has less PPARγ-related adverse effects compared with Rosiglitazone. DS-6930 has research value in diabetes.
价 格:¥电议型 号:T61976产 地:中国大陆
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T60930CAXII-IN-1;化合物 CAXII-IN-1CAXII-IN-1
CAXII-IN-1 (Compound 17) has antitumor activity that is a selective inhibitor of CA XII. The Ki values of CAXII-IN-1 for hCA XII and hCA IX is 3.8 nM and 56.0 nM, respectively [1].
价 格:¥电议型 号:T60930产 地:中国大陆
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T5383D3-βArr;化合物D3-βArrNCGC00379308;NCGC00379308
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
价 格:¥电议型 号:T5383产 地:中国大陆
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T5345V-9302;化合物V-9302V-9302
V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM).
价 格:¥电议型 号:T5345产 地:中国大陆
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T4930ISOBUTYRALDEHYDE OXIME;異丁醛肟ISOBUTYRALDEHYDE OXIME
2-methylpropanal oxime is an aldoxime derived from 2-methylpropanal. It derives from an isobutyraldehyde.
价 格:¥电议型 号:T4930产 地:中国大陆
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T4285Crisaborole;克立硼罗AN-2728|||PF-06930164;克立硼罗|||AN-2728|||PF-06930164
Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.
价 格:¥电议型 号:T4285产 地:中国大陆
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T40930(S)-Sitagliptin phosphate;(S)-Sitagliptin phosphate(S)-Sitagliptin phosphate|||(S)-MK-0431 phosphate
(S)-Sitagliptin phosphate, the less active S-enantiomer of Sitagliptin phosphate, is a high-potency inhibitor of DPP4. It exhibits an IC50 of 19 nM in Caco-2 cell extracts.
价 格:¥电议型 号:T40930产 地:中国大陆
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T40064V-9302 hydrochloride;V-9302 hydrochlorideV-9302 hydrochloride
V-9302 hydrochloride is a potent and selective competitive antagonist that inhibits transmembrane glutamine flux by specifically targeting the amino acid transporter ASCT2 (SLC1A5), and not ASCT1. In HEK-293 cells, V-9302 hydrochloride effectively inhibits ASCT2-mediated glutamine uptake with an IC50 value of 9.6 μM.
价 格:¥电议型 号:T40064产 地:中国大陆
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T39930MS98;MS98MS98
MS98 is a highly effective and specific PROTAC AKT degrader compound that effectively targets and depletes total AKT (T-AKT) within cells, exhibiting a DC 50 value of 78 nM. This compound readily binds to AKT1, AKT2, and AKT3 with respective dissociation constants (Kd s) of 4 nM, 140 nM, and 8.1 nM.
价 格:¥电议型 号:T39930产 地:中国大陆
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T39309Telaglenastat hydrochlorideTelaglenastat hydrochlorideCB-839 hydrochloride
Telaglenastat (CB-839) hydrochloride is a first-in-class, reversible, and orally active inhibitor of glutaminase 1 (GLS1). It selectively inhibits the splice variants of GLS1, specifically KGA (kidney-type glutaminase) and GAC (glutaminase C), as compared to GLS2. Telaglenastat hydrochloride has an IC50 of 23 nM for endogenous glutaminase in mouse kidney and 28 nM in the brain. In addition, it induces autophagy and exhibits antitumor activity.
价 格:¥电议型 号:T39309产 地:中国大陆
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T39308Boc-Asp(OMe)-fluoromethyl ketone;化合物Boc-Asp(OMe)-fluoromethyl ketoneBoc-Asp(OMe)-fluoromethyl ketone
Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
价 格:¥电议型 号:T39308产 地:中国大陆
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T39307Azido-PEG4-Val-Cit-PAB-MMAE;Azido-PEG4-Val-Cit-PAB-MMAEAzido-PEG4-Val-Cit-PAB-MMAE;Azido-PEG4-Val-Ci
Azido-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor), connected through the cleavable linker Azido-PEG4-Val-Cit-PAB-OH.
价 格:¥电议型 号:T39307产 地:中国大陆