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  • T78665FITC-labeled ODN 1826 sodium;化合物 FITC-labeled ODN 1826 sodiumFITC-labeled ODN 1826 sodium

    FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.

    价 格:¥电议型 号:T78665产 地:中国大陆

  • T78663FITC-labeled Agatolimod sodium;化合物 FITC-labeled Agatolimod sodiumFITC-labeled Agatolimod sodium

    FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization via confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.

    价 格:¥电议型 号:T78663产 地:中国大陆

  • T78311Sontuzumab;松妥组单抗huHMFG-1|||AS1402;huHMFG-1|||AS1402

    Sontuzumab (AS1402), a humanized IgG1κ monoclonal antibody targeting MUC1, exhibits high affinity, with a dissociation constant (Kd) of approximately 1 nM for the extracellular peptide sequence PDTR of MUC1. It is utilized in breast cancer research [1].

    价 格:¥电议型 号:T78311产 地:中国大陆

  • T78089FITC-labeled ODN 1018 sodium;化合物 FITC-labeled ODN 1018 sodiumFITC-labeled ODN 1018 sodium

    FITC-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.

    价 格:¥电议型 号:T78089产 地:中国大陆

  • T77109Omfiloctocog alfa;化合物 Omfiloctocog alfaOmfiloctocog alfa

    Omfiloctocog alfa (SCT-800), a recombinant factor VIII (FVIII), is an essential protein for blood coagulation and a critical element of the fluid phase blood coagulation system. It is utilized in the research of Hemophilia A [1] [2].

    价 格:¥电议型 号:T77109产 地:中国大陆

  • T76877Vofatamab;沃凡妥单抗RG-7444|||B-701|||MFGR-1877S;RG-7444|||B-701|||MFGR-1877S

    Vofatamab (B-701) is a fully human monoclonal antibody targeting FGFR3. Vofatamab has potential anticancer and antitumor activity and is often used in combination with other compounds to treat cancer.

    价 格:¥电议型 号:T76877产 地:中国大陆

  • T75630Ganoderic acid Mf;化合物 Ganoderic acid MfGanoderic acid Mf

    Ganoderic acid Mf, an antitumor triterpenoid, selectively induces apoptosis in cancer cells through a mitochondria-mediated pathway while demonstrating high selectivity between normal and cancer cells. It also arrests the cell cycle in the G1 phase [1].

    价 格:¥电议型 号:T75630产 地:中国大陆

  • T75370CellTracker Blue CMF2HC Dye;化合物 CellTracker Blue CMF2HC DyeCellTracker Blue CMF2HC Dye

    CellTracker Blue CMF2HC Dye, a blue dye suitable for two-channel nuclei acid sequencing using blue and purple excitation light (450-460 nm/400-405nm or 415-450 nm/480-525nm), facilitates rapid determination of microorganisms´ antibiotic sensitivity [1] [2]. Storage instructions recommend protection from light.

    价 格:¥电议型 号:T75370产 地:中国大陆

  • T75084Foslevcromakalim;化合物 FoslevcromakalimFoslevcromakalim

    Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].

    价 格:¥电议型 号:T75084产 地:中国大陆

  • T74088Fludarabine triphosphate trisodium;化合物 Fludarabine triphosphate trisodiumFludarabine triphosphate tr

    Fludarabine triphosphate (F-ara-ATP) trisodium, the principal metabolite of Fludarabine, acts as a potent, noncompetitive, and specific inhibitor of DNA primase, exhibiting an IC50 value of 2.3 μM and a Ki of 6.1 μM. It hampers DNA synthesis by obstructing DNA primase and the formation of primer RNA, while also inhibiting ribonucleotide reductase and DNA polymerase activities, effectively inducing cellular apoptosis [1] [2].

    价 格:¥电议型 号:T74088产 地:中国大陆

  • T71822B-TPMF;化合物 B-TPMFB-TPMF

    B-TPMF is the first small-molecule inhibitor with significant selectivity among the KCa2 channel subtypes.

    价 格:¥电议型 号:T71822产 地:中国大陆

  • T71628Fluvastatin potassium;化合物 Fluvastatin potassiumFluvastatin potassium

    Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class.

    价 格:¥电议型 号:T71628产 地:中国大陆

  • T71524Famiraprinium;化合物 FamirapriniumFamiraprinium

    Famiraprinium is a competitive antagonist at the GABA receptor site.

    价 格:¥电议型 号:T71524产 地:中国大陆

  • T71510MF-592;化合物 MF-592MF-592

    MF-592 is a potent and selective antagonists of the EP4 receptor. MF-592 demonstrated good functional potency (hEP4 IC50 = 3 nM) and potent inhibition of PGE2 modulated TNFa release in LPS stimulated human whole blood (hWB) (IC50 = 78nM). In addition, it showed an excellent oral pharmacokinetic (PK) profile and in vivo efficacy in a rat chronic adjuvant-induced-arthritis model (ED50 = 0.1 mg/kg/day).. MF-592 has a desirable overall preclinical profile that suggests it is suitable for further de

    价 格:¥电议型 号:T71510产 地:中国大陆

  • T71306Gemfibrozil-d6;化合物 Gemfibrozil-d6Gemfibrozil-d6

    Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif l

    价 格:¥电议型 号:T71306产 地:中国大陆

  • T71215Faldaprevir sodium;化合物 Faldaprevir sodiumFaldaprevir sodium

    Faldaprevir sodium is a potent NS3/NS4A protease inhibitor potentially for the treatment of HCV infection. Faldaprevir is known to inhibit P-glycoprotein, CYP3A4, and UDP-glucuronosyltransferase 1A1.

    价 格:¥电议型 号:T71215产 地:中国大陆

  • T70974Cipamfylline;化合物 CipamfyllineCipamfylline

    Cipamfylline is a xanthine, a theophylline analogue, and is a potent and selective inhibitor of phosphodiesterase type 4 (PDE-4). Cipamfylline was tested in patients with a diagnosis of atopic dermatitis and in two human models of acute and chronic irritant contact dermatitis. The outcome of the study revealed that cipamfylline was more effective than vehicle in treating atopic dermatitis, but less effective than a group II steroid, hydrocortisone-17-butyrate both in the treatment of atopic derm

    价 格:¥电议型 号:T70974产 地:中国大陆

  • T70855Favipiravir sodium;化合物 Favipiravir sodiumFavipiravir sodium

    Favipiravir sodium is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses.

    价 格:¥电议型 号:T70855产 地:中国大陆

  • T70465Mf 268;化合物 Mf 268Mf 268

    Mf 268 is a pseudo-reversible carbamate-type inhibitor which interacts with the catalytic and regulatory anionic site of the enzyme.

    价 格:¥电议型 号:T70465产 地:中国大陆

  • T69931MFH290;化合物 MFH290MFH290

    MFH290 is a novel cysteine (Cys)-directed covalent inhibitor of CDK12/13. MFH290 forms a covalent bond with Cys-1039 of CDK12, exhibits excellent kinome selectivity, inhibits the phosphorylation of serine-2 in the C-terminal domain (CTD) of RNA-polymerase II (Pol II), and reduces the expression of key DNA damage repair genes. Importantly, these effects were demonstrated to be CDK12-dependent as mutation of Cys-1039 rendered the kinase refractory to MFH290 and restored Pol II CTD phosphorylation

    价 格:¥电议型 号:T69931产 地:中国大陆

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