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T80259PMAP-23;化合物 PMAP-23PMAP-23
PMAP-23 is an antimicrobial peptide (AMP) with biological activity, derived from porcine myeloid cells.
价 格:¥电议型 号:T80259产 地:中国大陆
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T79602MTP;化合物 MTPMTP
MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation. Further, it inhibits JAK2 signaling, rendering it useful for the study of oral squamous cell carcinoma [1].
价 格:¥电议型 号:T79602产 地:中国大陆
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T78901PPM-3;化合物 PPM-3PPM-3
PPM-3, a selective PROTAC ERK5 degrader, exhibits a potent inhibitory concentration (IC 50) of 62.4 nM. While not directly inhibiting tumor cell growth, PPM-3 affects tumor progression through influencing macrophage differentiation [1].
价 格:¥电议型 号:T78901产 地:中国大陆
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T77870Mal-Val-Ala-PABA-cGAMP;化合物 Mal-Val-Ala-PABA-cGAMPMal-Val-Ala-PABA-cGAMP
Mal-Val-Ala-PABA-cGAMP serves as an ADC linker for attachment to STING agonists and is utilized in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T77870产 地:中国大陆
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T77868Mal-amide-PEG8-Val-Ala-PAB-PNP;化合物 Mal-amide-PEG8-Val-Ala-PAB-PNPMal-amide-PEG8-Val-Ala-PAB-PNP
Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable linker utilized in the production of antibody-drug conjugates (ADCs), facilitating the attachment of cytotoxic drugs to antibodies for targeted delivery [1].
价 格:¥电议型 号:T77868产 地:中国大陆
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T76066Lpm26TGF-β1 peptide TFA;化合物 pm26TGF-β1 peptide TFApm26TGF-β1 peptide TFA
pm26TGF-β1 TFA peptide is a synthetic peptide that emulates a segment of the human TGF-β1 molecule, demonstrating high affinity for the TGF-β1 receptor. It possesses potent anti-inflammatory capabilities while lacking the ability to attract neutrophils [1] [2].
价 格:¥电议型 号:T76066L产 地:中国大陆
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T76066pm26TGF-β1 peptide;化合物 pm26TGF-β1 peptidepm26TGF-β1 peptide
pm26TGF-β1 peptide, mimicking a portion of the human TGF-β1 molecule, demonstrates a high affinity for the TGF-β1 receptor. It exhibits potent anti-inflammatory properties without inducing neutrophils´ chemoattraction [1] [2].
价 格:¥电议型 号:T76066产 地:中国大陆
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T75521PM050489;化合物 PM050489PM050489
PM050489, a potent polyketone inhibitor of Microtubule/Tubulin isolated from the Madagascan sponge Lithoplocamia lithistoides, effectively inhibits mitosis with an IC 50 value of 26.4 nM. This compound exhibits antitumor activity, making it relevant for cancer research [1] [2].
价 格:¥电议型 号:T75521产 地:中国大陆
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T75421alpha-2,3-Sialyltransferase (PmST3);化合物 alpha-2,3-Sialyltransferase (PmST3)alpha-2,3-Sialyltransfera
alpha-2,3-Sialyltransferase (PmST3) is a beta-galactoside. alpha-2,3-Sialyltransferase (PmST3) catalyzes the transfer of sialic acid to carbohydrate groups of glycoproteins and glycolipids [1] .
价 格:¥电议型 号:T75421产 地:中国大陆
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T75416alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138);化合物 alpha-1,3-N-Acetylgalactosaminyltransferase
Alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also known as the ABO system transferase, exhibits glycosyl transferase activity [1].
价 格:¥电议型 号:T75416产 地:中国大陆
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T75397Hyaluronan synthase (PmHAS);化合物 Hyaluronan synthase (PmHAS)Hyaluronan synthase (PmHAS)
Hyaluronan synthase (PmHAS), a membrane protein, catalyzes the biosynthesis of hyaluronic acid (HA) by utilizing only Mg+2 along with two sugar-UDP substrates, GlcUA-UDP and GlcNAc-UDP, to polymerize HA chains [1] [2].
价 格:¥电议型 号:T75397产 地:中国大陆
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T74646PM-81I;化合物 PM-81IPM-81I
PM-81I, a potent STAT6 inhibitor targeting the SH2 structural domain, effectively reduces STAT6 phosphorylation levels. It is applicable in the research of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease, or cancer [1].
价 格:¥电议型 号:T74646产 地:中国大陆
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T74474m7Gpppm6AmpG ammonium;化合物 m7Gpppm6AmpG ammoniumm7Gpppm6AmpG ammonium
M7Gpppm6AmpG ammonium, a trinucleotide mRNA 5’ cap analog, facilitates in vitro RNA synthesis [1].
价 格:¥电议型 号:T74474产 地:中国大陆
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T74473m7Gpppm6AmpG;化合物 m7Gpppm6AmpGm7Gpppm6AmpG
m7Gpppm6AmpG, a trinucleotide mRNA 5’ cap analog, facilitates RNA synthesis in vitro [1].
价 格:¥电议型 号:T74473产 地:中国大陆
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T73710PMX 205 Trifluoroacetate;化合物 PMX 205 TrifluoroacetatePMX 205 Trifluoroacetate
PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.
价 格:¥电议型 号:T73710产 地:中国大陆
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T73568MTEP;化合物 MTEPMTEP
MTEP, a potent, non-competitive, and highly selective antagonist of mGluR5, exhibits an IC50 value of 5 nM and a K_i value of 16 nM. Demonstrating antidepressant and anxiolytic-like effects, MTEP is utilized in Parkinson´s disease research.
价 格:¥电议型 号:T73568产 地:中国大陆
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T73544MPM-1;化合物 MPM-1MPM-1
MPM-1, a mimic of marine Eusynstyelamides, serves as an effective anticancer agent. It swiftly induces a necrosis-like death in cancer cells in vitro, facilitates immunogenic cell death, and disrupts autophagy, leading to lysosomal swelling in cancer cells.
价 格:¥电议型 号:T73544产 地:中国大陆
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T72662NMDAR/TRPM4-IN-2;化合物NMDAR/TRPM4-IN-2NMDAR/TRPM4-IN-2
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprotective activity against NMDA-induced hippocampal neuronal cell death and mitochondrial dysfunction. NMDAR/TRPM4-IN-2 showed neuroprotective activity against NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons with an IC50 value of 2.1 μM.
价 格:¥电议型 号:T72662产 地:中国大陆
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T72216DPM-1001 trihydrochloride;化合物 DPM-1001 trihydrochlorideDPM-1001 trihydrochloride
DPM-1001 trihydrochloride, an analog of the specific protein-tyrosine phosphatase (PTP1B) inhibitor MSI-1436, is a potent, specific, non-competitive, orally active inhibitor of PTP1B with an IC50 of 100 nM, exhibiting anti-diabetic properties.
价 格:¥电议型 号:T72216产 地:中国大陆
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T71822B-TPMF;化合物 B-TPMFB-TPMF
B-TPMF is the first small-molecule inhibitor with significant selectivity among the KCa2 channel subtypes.
价 格:¥电议型 号:T71822产 地:中国大陆