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T4260Capmatinib 2HCl;INCB28060盐酸盐INC-280 2HCl|||INCB28060 2HCl;INC-280 2HCl|||INCB28060盐酸盐|||INCB28060 2H
Capmatinib 2HCl (INC-280 2HCl) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.Capmatinib 2HCl exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines. As a result, Capmatinib 2HCl potently inhibits c-MET-dependent tumor cell proliferation a
价 格:¥电议型 号:T4260产 地:中国大陆
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T4172Methoxy-PMS;化合物1-Methoxy PMS1-Methoxyphenazine methosulfate|||1-Methoxy PMS;1-Methoxyphenazine metho
Methoxy-PMS (1-Methoxyphenazine methosulfate) is stable electron-transport mediator between NAD(P)H and tetrazolium dyes, can induce active oxygen formation.
价 格:¥电议型 号:T4172产 地:中国大陆
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T41269PMK ethyl glycidate;化合物 PMK ethyl glycidatePMK ethyl glycidate
PMK ethyl glycidate has a wide range of applications in life science related research.
价 格:¥电议型 号:T41269产 地:中国大陆
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T41173FAM-DEALAHypYIPMDDDFQLRSF;FAM-DEALAHypYIPMDDDFQLRSFFAM-DEALAHypYIPMDDDFQLRSF
FAM-DEALAHypYIPMDDDFQLRSF is a 5,6-carboxyfluorescein (FAM) labeled HIF-1α peptide. It binds with high affinity to von Hippel-Lindau (VHL) protein (KD= 3 nM). Can be used to assess ligand binding to VHL in a direct fluorescence polarization (FP) displacement assay. Excitation/emission maxima (λ) = 485/520 nm. This product is a longer peptide version of FAM-DEALA-Hyp-YIPD.
价 格:¥电议型 号:T41173产 地:中国大陆
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T41060AnsofaxineAnsofaxineAnsofaxine|||LPM570065freebase|||Toludesvenlafaxine|||LY03005freebase
Ansofaxine, an SNRI compound, is commonly utilized in depression research as a serotonin-norepinephrine reuptake inhibitor.
价 格:¥电议型 号:T41060产 地:中国大陆
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T40632MS-PEG12-THP;MS-PEG12-THPMS-PEG12-THP;MS-PEG12-THP
MS-PEG12-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40632产 地:中国大陆
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T40575ADPM06;ADPM06ADPM06
ADPM06, an azadipyrromethene compound, is a new nonporphyrin photodynamic therapeutic (PDT) agent with potential as a lead candidate. It demonstrates significant IC50 values in the micro-molar range in human tumor cells, as well as inducing apoptosis.
价 格:¥电议型 号:T40575产 地:中国大陆
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T40532MS-PEG10-THP;MS-PEG10-THPMS-PEG10-THP;MS-PEG10-THP
MS-PEG10-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40532产 地:中国大陆
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T40530Ms-PEG6-THP;Ms-PEG6-THPMs-PEG6-THP;Ms-PEG6-THP
Ms-PEG6-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40530产 地:中国大陆
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T40448MS-PEG3-THP;MS-PEG3-THPMS-PEG3-THP;MS-PEG3-THP
MS-PEG3-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40448产 地:中国大陆
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T40396FgGpmk1-IN-1FgGpmk1-IN-1FgGpmk1-IN-1
FgGpmk1-IN-1 is a new inhibitor of the fusarium graminearum mitogen-activated protein kinase (FgGpmk1), displaying a potency with an EC50 value of 3.46 μg/mL.
价 格:¥电议型 号:T40396产 地:中国大陆
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T39765Mal-PEG1-Val-Cit-PAB-PNP;Mal-PEG1-Val-Cit-PAB-PNPMal-PEG1-Val-Cit-PAB-PNP;Mal-PEG1-Val-Cit-PAB-PNP
Mal-PEG1-Val-Cit-PAB-PNP is an ADC linker employed in the synthesis of ADCs, enabling cleavage.
价 格:¥电议型 号:T39765产 地:中国大陆
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T39478L-threo-PPMP;L-threo-PPMPL-threo-PPMP
L-threo-PPMP is an inhibitor of GlcT, which is the UDP-Glc: Ceramide β1,1glucosyltransferase enzyme. It effectively inhibits glycosphingolipid biosynthesis, while also inducing apoptosis. These properties of L-threo-PPMP contribute to its notable anti-cancer activity.
价 格:¥电议型 号:T39478产 地:中国大陆
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T38948MS-PEG4-THP;化合物MS-PEG4-THPMS-PEG4-THP
MS-PEG4-THP is a PROTAC linker, which is a PEG type.
价 格:¥电议型 号:T38948产 地:中国大陆
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T38896VPM peptide;VPM peptideVPM peptide
VPM peptide functions as a protease-cleavable dithiol cross-linker. It is capable of integration into the PEG-diacrylate (PEG-DA) macromer backbone, resulting in the formation of PEG hydrogel.
价 格:¥电议型 号:T38896产 地:中国大陆
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T38822D-threo-PPMP;D-threo-PPMPD-threo-PPMP
D-threo-PPMP, a powerful glucosylceramide (GlcCer) synthase inhibitor, effectively impedes karyokinesis and decreases cyst formation.
价 格:¥电议型 号:T38822产 地:中国大陆
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T38739Mal-PEG2-Val-Cit-PABA-PNP;Mal-PEG2-Val-Cit-PABA-PNPMal-PEG2-Val-Cit-PABA-PNP;Mal-PEG2-Val-Cit-PABA-P
Mal-PEG2-Val-Cit-PABA-PNP is a cleavable linker compound employed in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T38739产 地:中国大陆
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T38705MS-PEG1-THP;MS-PEG1-THPMS-PEG1-THP;MS-PEG1-THP
MS-PEG1-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T38705产 地:中国大陆
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T38608Brilacidin tetrahydrochloride;Brilacidin tetrahydrochloridePMX 30063 tetrahydrochloride;PMX 30063 te
Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is a defensin mimetic antibiotic compound, exhibiting potent anti-infective antimicrobial activity against a range of bacteria. It demonstrates MIC90 values of 1 μg/mL and 8 μg/mL against the Gram-positive bacteria Streptococcus pneumoniae and Streptococcus viridans, respectively. Additionally, it has a MIC90 value of 8 μg/mL for the Gram-negative bacteria Haemophilus influenzae and a MIC90 value of 4 μg/mL for Pseudomonas aeruginosa.
价 格:¥电议型 号:T38608产 地:中国大陆
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T38164MnTBAP chloride;化合物Mn(III)TBAPMn(III)TBAP;Mn(III)TBAP
MnTBAP chloride (Mn(III)TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2. MnTBAP chloride exhibits anti-inflammatory effects through upregulation of BMPR-II and inhibition of NFκB signaling. mnTBAP chloride is a manganese porphyrin complex with antioxidant properties and has potential for use in the study of fibrotic responses in chronic kidney diseases (CKDs).
价 格:¥电议型 号:T38164产 地:中国大陆