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T35774HC Toxin;HC ToxinHC Toxin
HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells. HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.
价 格:¥电议型 号:T35774产 地:中国大陆
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T3574Sematilide hydrochloride;司美利特CK-1752A|||CK-1752|||Sematilide HCl;司美利特|||CK-1752A|||CK-1752|||Sematil
Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of refractoriness and action potential duration.
价 格:¥电议型 号:T3574产 地:中国大陆
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T35528LTD52 dihydrochloride;化合物TD52盐酸盐TD52 dihydrochloride(1798328-24-1 Free base)|||TD52 2HCl;TD52 dihydro
TD52 dihydrochloride (TD52 2HCl), a derivative of Erlotinib, is a potent and orally active inhibitor of protein phosphatase 2A (CIP2A). It exhibits strong anti-cancer properties by regulating the CIP2A/PP2A/p-Akt signaling pathway, resulting in the induction of apoptosis in triple-negative breast cancer (TNBC) cells. Mechanistically, TD52 dihydrochloride disrupts the binding of Elk1 to the CIP2A promoter, effectively reducing CIP2A levels. Notably, TD52 dihydrochloride demonstrates powerful anti
价 格:¥电议型 号:T35528L产 地:中国大陆
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T3552CPI-455;化合物CPI455CPI-455 HCl;CPI-455 HCl
CPI-455 is a specific KDM5 inhibitor.
价 格:¥电议型 号:T3552产 地:中国大陆
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T35348LDN-193189 2HCl乙磺普隆LDN-193189 2HCl|||DM-3189 2HCl
LDN-193189 2HCl (DM-3189 2HCl) is a selective BMP signaling inhibitor that inhibits ALK1,ALK2,ALK3 and ALK6, showing IC50s of 0.8 nM, 0.8 nM, 5.3 nM, and 16.7 nM, respectively, in kinase assays.LDN-193189 2HCl inhibited the transcriptional activity of BMP type I receptors in C2C12 cells, with IC50s of 5 nM and 30 nM, respectively. LDN-193189 2HCl inhibited the transcriptional activity of BMP type I receptors ALK2 and ALK3 in C2C12 cells, with IC50s of 5 nM and 30 nM, respectively, and was 200-fo
价 格:¥电议型 号:T35348产 地:中国大陆
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T35332THZ1 2HCl;THZ1二盐酸盐THZ1 2HCl|||THZ1 Dihydrochloride;THZ1二盐酸盐|||THZ1 2HCl|||THZ1 Dihydrochloride
THZ1 2HCl (THZ1 Dihydrochloride) is a selective, covalent, and allosteric inhibitor of CDK7 with an IC50 of 3.2 nM. THZ1 2HCl has antiproliferative effects on a variety of cancer cell lines.
价 格:¥电议型 号:T35332产 地:中国大陆
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T35329LEAD1 TFA(1644388-26-0 Free base);化合物 EAD1 TFAEAD1 HCL(1644388-26-0 Free base);EAD1 HCL(1644388-26-0
EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis
价 格:¥电议型 号:T35329L产 地:中国大陆
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T35328H-1152 dihydrochloride;化合物H-1152二盐酸盐H-1152 2HCl|||H-1152 dihydrochloride;H-1152 2HCl|||H-1152 dihydr
H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 values of 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
价 格:¥电议型 号:T35328产 地:中国大陆
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T35271Yoshi-864;化合物 T35271Yoshi864|||Improsulfan HCl|||NSC102627|||Improsulfan hydrochloride;Yoshi864|||Im
Yoshi-864 alkylates and cross-links DNA, thereby inhibiting DNA replication. It is an alkyl sulfonate DNA cross-linking agent with potential anti-cancer activity.
价 格:¥电议型 号:T35271产 地:中国大陆
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T3518GSK269962A;化合物GSK269962AGSK269962B|||GSK 269962|||GSK269962A HCl;GSK269962B|||GSK 269962|||GSK269962
GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
价 格:¥电议型 号:T3518产 地:中国大陆
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T3515TRC051384 HCl;化合物TRC051384 HClTRC051384 HCl
TRC051384 HCl is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.
价 格:¥电议型 号:T3515产 地:中国大陆
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T3512S49076 HCl;化合物S49076 HClS-49076 Hydrochloride;S-49076 Hydrochloride
S49076 HCl (S-49076 Hydrochloride) is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 HCl potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in vivo. In cell models, S49076 HCl inhibited the proliferation of MET- and FGFR2-dependent gastric cancer cells blocked MET-driven migration of lung carcinoma cells, and inhibited colony formation of hepatocarcinoma cells expressing FGFR1/2 and AXL. In tumor xenograft models, a goo
价 格:¥电议型 号:T3512产 地:中国大陆
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T35045Velnacrine;维吖啶1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate|||1-hydroxytacrine|||9-ATHCO|||9-amino-
Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.
价 格:¥电议型 号:T35045产 地:中国大陆
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T34979U-34728E (HCl);化合物 T34979U 34728E (HCl);U 34728E (HCl)
U-34728E (HCl) is a bioactive chemical.
价 格:¥电议型 号:T34979产 地:中国大陆
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T34945Trimazosin hydrochloride;化合物 T34945CP19106-1|||CP 19106-1|||Trimazosin HCl|||CP-19106-1;CP19106-1|||
Trimazosin hydrochloride is used in the treatment of hypertensive patients failing to respond to thiazides.
价 格:¥电议型 号:T34945产 地:中国大陆
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T34934Trichovirin I IB;化合物 T34934Harzianin HC I;Harzianin HC I
Trichovirin I IB is a peptaibiotic, alpha-aminobutyric acid-rich secondary metabolite of fungi.
价 格:¥电议型 号:T34934产 地:中国大陆
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T34921LTresperimus HCl;化合物 T34921LTresperimus trihydrochloride|||LF08-0299 trihydrochloride|||LF 08-0299 tr
Tresperimus HCl can induce tolerance after the short-term treatment in a fully major histocompatibility mismatched rat cardiac allograft model.
价 格:¥电议型 号:T34921L产 地:中国大陆
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T34912TPT197 HCl;化合物 T34912TPT 197|||TPT197;TPT 197|||TPT197
TPT-197 is a thiophene thiourea derivative with molecule weight 197 in free base form. There is no formal name yet, we temporally call this molecule as TPT-197. Please also see similar products: TPT-197; TPT-260; TPT-172.
价 格:¥电议型 号:T34912产 地:中国大陆
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T34911TPT-172 HCl (R33);化合物 T34911TPT 172|||TPT172|||TPT-172|||thiophene thiourea derivative. R33;TPT 172|
TPT-172, also known as R33 (described in Mecozzi et al´ s paper), is a thiophene thiourea derivative with molecule weight 172 in free base form. There is no formal name yet, we temporally call this molecule as TPT-172. Please also see similar products: TPT-197; TPT-260; TPT-172.
价 格:¥电议型 号:T34911产 地:中国大陆
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T34911400W dihydrochloride;化合物1400W dihydrochloride1400W 2HCl|||N-(3-(Aminomethyl)benzyl)acetamidine;1400
1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).
价 格:¥电议型 号:T3491产 地:中国大陆