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T4417LDC-4297 HCl (1453834-21-3(free base));化合物LDC-4297 HClLDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
价 格:¥电议型 号:T4417产 地:中国大陆
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T4403AX-024 hydrochloride;化合物AX-024 HClAX-024 HCl;AX-024 HCl
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
价 格:¥电议型 号:T4403产 地:中国大陆
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T4400DIM-C-pPhOH;化合物DIM-C-pPhOHCDIM8;CDIM8
DIM-C-pPhOH (CDIM8) is a nur77 (NR4A1) antagonist,inhibits TGF-β induced cell migration of breast cancer cell lines,promotes ROS/endoplasmic reticulum stress and proapoptotic pathways in pancreatic cancer cell lines,mimics effects of Nur77 RNAi silencing.
价 格:¥电议型 号:T4400产 地:中国大陆
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T4393MS049 2HCl (1502816-23-0(free base));化合物MS049 2HClMS049 2HCl (1502816-23-0(free base))
MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220, and 1.6 μM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases or nonepigenetic targets tested.
价 格:¥电议型 号:T4393产 地:中国大陆
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T4383GSK-J4 Hydrochloride;化合物GSK-J4 HydrochlorideGSK J4 HCl|||GSK J4 HCl (1373423-53-0 free base);GSK J4
GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester derivative of the GSK-J1 with an IC50 value greater than 50 μM in vitro.
价 格:¥电议型 号:T4383产 地:中国大陆
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T4377LPimodivir HCl;化合物 T4377LPimodivir hydrochloride hemihydrate|||Pimodivir hydrochloride;Pimodivir hydr
Pimodivir is an inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. The cell-based EC50 for VX-787 is 1.6 nM in a cytopathic effect (CPE) assay. VX-787 is active against a diverse panel of influenza A virus strains.
价 格:¥电议型 号:T4377L产 地:中国大陆
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T4345CeMMEC1化合物CeMMEC1CeMMEC1 HCl
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
价 格:¥电议型 号:T4345产 地:中国大陆
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T4334EPZ020411 2HCl (1700663-41-7(free base));化合物EPZ020411 2HClEPZ020411 2HCl (1700663-41-7(free base))
EPZ020411 is an effective and specific small molecule PRMT6 inhibitor (IC50=10 nM).
价 格:¥电议型 号:T4334产 地:中国大陆
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T4314EPZ020411;化合物EPZ020411EPZ020411 2HCl;EPZ020411 2HCl
EPZ020411 is a specific and effective inhibitor of PRMT6 (IC50=10 nM).
价 格:¥电议型 号:T4314产 地:中国大陆
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T4291(+)-Isocorydine hydrochloride;盐酸异可利定Isocorydine HCl;盐酸异可利定|||Isocorydine HCl
(+)-Isocorydine hydrochloride (Isocorydine HCl) is a eukaryote protein kinases Inhibitor.
价 格:¥电议型 号:T4291产 地:中国大陆
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T4276Hydroxyfasudil Hydrochloride羟基法舒地尔盐酸盐Hydroxyfasudil (HA-1100) HCl|||羟基法舒地尔盐酸盐|||RHO-激酶抑制剂|||HA 1100
Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).
价 格:¥电议型 号:T4276产 地:中国大陆
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T4260Capmatinib 2HCl;INCB28060盐酸盐INC-280 2HCl|||INCB28060 2HCl;INC-280 2HCl|||INCB28060盐酸盐|||INCB28060 2H
Capmatinib 2HCl (INC-280 2HCl) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.Capmatinib 2HCl exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines. As a result, Capmatinib 2HCl potently inhibits c-MET-dependent tumor cell proliferation a
价 格:¥电议型 号:T4260产 地:中国大陆
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T4236AR-M 1000390 hydrochloride化合物AR-M 1000390 hydrochlorideARM390 Hydrochloride|||ARM-390 HCl
AR-M 1000390 hydrochloride (ARM-390 HCl) , also known as ARM-390, is a low-internalizing nonpeptidic δ-selective opioid receptor agonist; derivative of SNC 80. Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.
价 格:¥电议型 号:T4236产 地:中国大陆
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T4211SAG hydrochloride (912545-86-9(free base));化合物SAG hydrochlorideSmoothened Agonist HCl;Smoothened Ago
SAG hydrochloride (912545-86-9(free base)) (Smoothened Agonist HCl) acts as an SMO agonist.
价 格:¥电议型 号:T4211产 地:中国大陆
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T4134LOTS514;化合物OTS514OTS514 HCl|||OTS514 Hydrochloride|||OTS-514|||OTS 514;OTS514 HCl|||OTS514 Hydrochlor
OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM). Treatment with OTS514 suppressed forkhead box protein M1 (FOXM1) activity. OTS514 treatment reduced CD90-positive SCLC cells and showed a higher cytotoxic effect against lung sphere-derived CSC-like SCLC cells.
价 格:¥电议型 号:T4134L产 地:中国大陆
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T41116FV-100;化合物FV-100Valnivudine HCl;Valnivudine HCl
FV-100 (Valnivudine HCl) is a potent, selective and orally active anti-vaxx-zoster agent.FV-100 is the API for CF-1743.FV-100 exhibits very low toxicity in vivo.FV-100 is a potent, selective and orally active anti-vaxx-zoster agent.FV-100 is the API for CF-1743.FV-100 exhibits very low toxicity in vivo.
价 格:¥电议型 号:T41116产 地:中国大陆
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T41002HCVP-IN-1;HCVP-IN-1HCVP-IN-1
HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.
价 格:¥电议型 号:T41002产 地:中国大陆
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T4097Vardenafil hydrochloride trihydrate盐酸瓦地那非三水合物Vardenafil HCl Trihydrate|||BAY38-9456|||盐酸瓦地那非三水合物
Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
价 格:¥电议型 号:T4097产 地:中国大陆
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T40935CH2COOH-PEG6-CH2COOHCH2COOH-PEG6-CH2COOHCH2COOH-PEG6-CH2COOH
CH2COOH-PEG6-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40935产 地:中国大陆
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T40898DMHCA;DMHCADMHCA
DMHCA, a potent, selective LXR agonist, specifically activates the LXR pathway´s cholesterol efflux arm, avoiding triglyceride synthesis stimulation. This compound exhibits anti-inflammatory properties and is utilized in researching cholesterol homeostasis and diabetes.
价 格:¥电议型 号:T40898产 地:中国大陆