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T61237hCAIX-IN-6;化合物 hCAIX-IN-6hCAIX-IN-6
Compounds 6B and 14g showed significant inhibitory effect on tumor related subtype HCA IX with low nanomolar potency, while 6K was effective on HCA XII. Compounds 6B, 14g and 6K can be considered as the leading molecules for the development of future cancer therapeutic drugs based on new mechanisms of action.
价 格:¥电议型 号:T61237产 地:中国大陆
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T61219hCAXII-IN-1;化合物 hCAXII-IN-1hCAXII-IN-1
hCAXII-IN-1 demonstrates selective inhibition of tumor-related subtypes HCA IX and XII, making it potential leading molecules in the development of novel cancer therapeutic drugs with new mechanisms of action.
价 格:¥电议型 号:T61219产 地:中国大陆
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T61164hCAII-IN-3;化合物 hCAII-IN-3hCAII-IN-3
hCAII-IN-3 (Compound 16) is an inhibitor of human carbonic anhydrase (hCA). It exhibits high affinity for hCA I, hCA II, hCA IX, and hCA XII, with Ki values of 403.8 nM, 5.1 nM, 10.2 nM, and 5.2 nM, respectively. Notably, hCA IX-IN-2 demonstrates anticancer activity [1].
价 格:¥电议型 号:T61164产 地:中国大陆
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T61015hCAIX/XII-IN-2;化合物 hCAIX/XII-IN-2hCAIX/XII-IN-2
hCAIX/XII-IN-2 (compound 6a) is a potent and selective inhibitor of hCAIX and hCAXII. The Ki values of hCAIX/XII-IN-2 for hCAI, hCAII, hCAIX and hCAXII are >10000, >10000, 30.0, 3.6 nM, respectively [1].
价 格:¥电议型 号:T61015产 地:中国大陆
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T6093LAZD7762 HCl;化合物 T6093LAZD7762 Hydrochloride;AZD7762 Hydrochloride
AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.
价 格:¥电议型 号:T6093L产 地:中国大陆
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T60921LPF-07038124 HCl(2415085-44-6 Free base);化合物 PF-07038124 HCl(2415085-44-6 Free base)PF-07038124 HCl(2
产品可用于生物细胞实验
价 格:¥电议型 号:T60921L产 地:中国大陆
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T60746hCAIX-IN-7;化合物 hCAIX-IN-7hCAIX-IN-7
hCAIX-IN-7 (compound 6c) is a potent and selective inhibitor of hCAIX which is the tumor associated isoforms. hCAIX-IN-7 inhibits hCAI, hCAII, hCAIV, hCAIX with KIs of >10000, >10000, 43.0, 410.6 nM, respectively [1].
价 格:¥电议型 号:T60746产 地:中国大陆
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T60745hCAIX-IN-5;hCAIX抑制剂5hCAIX-IN-5
hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.
价 格:¥电议型 号:T60745产 地:中国大陆
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T60739LY13g dihydrochloride;化合物 Y13g dihydrochlorideY13g 2HCl(T60739 Free base);Y13g 2HCl(T60739 Free base)
Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer´s disease (AD) progression are related). Y13g dihydrochloride reverses STZ-induced memory deficits and exhibits histopathology similar to normal animals.
价 格:¥电议型 号:T60739L产 地:中国大陆
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T6069Gemcitabine hydrochloride;盐酸吉西他滨Gemcitabine HCl|||Gemzar|||LY188011|||LY 188011 hydrochloride;Gemcit
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.
价 格:¥电议型 号:T6069产 地:中国大陆
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T6060LAnabasine HCl;化合物 T6060LBB-NC-0036|||CCG-38440|||H-8174|||AR-1H7273|||ZX-BK000320|||ST-24041653;BB-N
Anabasine HCl is used as a clinical biomarker for tobacco smoke exposure and as an insecticide. It is also a depolarizing NMJ blocker, aromatase inhibitor, nAChr antagonist, and teratogen found in species of Nicotiana.
价 格:¥电议型 号:T6060L产 地:中国大陆
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T60602hCAIX/XII-IN-5;化合物 hCAIX/XII-IN-5hCAIX/XII-IN-5
hCAIX/XII-IN-5 (Coumarin 9a) is an inhibitor of carbonic anhydrase (CA) that shows excellent hCA IX/XII selectivity with Kis of 93.3 and 85.7 nM over hCA I and hCA II, respectively. hCAIX/XII-IN-5 has anti-proliferative activities to cancer cells that can delay cell cycle and induce apoptosis [1].
价 格:¥电议型 号:T60602产 地:中国大陆
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T60450AChE/hCA I/II-IN-1;化合物 AChE/hCA I/II-IN-1AChE/hCA I/II-IN-1
AChE/hCA I/II-IN-1 (Compound 6) is a potent AChE/Hca inhibitor with IC50 values of 22.21, 60.79 and 66.64 nM for AChE, Hca Ⅰ and Hca Ⅱ. AChE/hCA I/II-IN-1 can be used in glaucoma, Alzheimer´s disease, and diabetes rsearch[1].
价 格:¥电议型 号:T60450产 地:中国大陆
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T60408hCA VB-IN-1;化合物 hCA VB-IN-1hCA VB-IN-1
hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].
价 格:¥电议型 号:T60408产 地:中国大陆
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T60405GSK-3036656 free base;化合物 GSK3036656GSK656 HCl|||GSK 3036656|||GSK656|||GSK-3036656|||GSK-656|||GSK
GSK656 (GSK3036656) shows potent inhibition of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS) (IC50 = 0.20 μM) which has potential for the treatment of tuberculosis [1].
价 格:¥电议型 号:T60405产 地:中国大陆
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T6018Zosuquidar trihydrochloride;唑喹达三盐酸盐Zosuquidar (LY335979) 3HCl|||RS 33295-198 trihydrochloride|||RS 3
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3.
价 格:¥电议型 号:T6018产 地:中国大陆
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T60112H-Glu(OEt)-OEt.HClL-谷氨酸二乙酯盐酸盐Diethyl L-glutamate hydrochloride|||(S)-Diethyl 2-aminopentanedioate hy
H-Glu(OEt)-OEt.HCl (Diethyl L-glutamate hydrochloride) is a glutamic acid derivative.
价 格:¥电议型 号:T60112产 地:中国大陆
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T60107N-0500 HCl;那高利特盐酸盐(-)-Propyl-9-hydroxynaphthoxazine Hydrochloride;(-)-Propyl-9-hydroxynaphthoxazine
N-0500 HCl ((-)-Propyl-9-hydroxynaphthoxazine Hydrochloride) is a very potent centrally acting DA receptor agonist. N-0500 HCl is a potent displacer of the specific [3H]DP5,6-ADTN binding with IC50 of 3nM.
价 格:¥电议型 号:T60107产 地:中国大陆
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T60102LDimethylaminomicheliolide HCl;化合物ATC001Dimethylaminomicheliolide HCl
Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate kinase 2 (PKM2) and reconnecting aerobic cell populations.
价 格:¥电议型 号:T60102L产 地:中国大陆
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T6010Idarubicin hydrochloride;盐酸伊达比星Idamycin|||4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl|||4-Demeth
Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).
价 格:¥电议型 号:T6010产 地:中国大陆