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T61832hCAI/II-IN-3；化合物 hCAI/II-IN-3hCAI/II-IN-3
hCAI/II-IN-3 (compound 5b) is a highly effective dual inhibitor of hCA I/II enzymes. It exhibits Ki values of 51.25, 13.15, and 42.18 nM for hCA I, hCA II, and hCA Ⅸ, respectively. hCAI/II-IN-3 demonstrates anti-hypoxic properties against acute mountain sickness (AMS) and exhibits low cellular activity [1].
价 格：￥电议型 号：T61832产 地：中国大陆
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T61769hCAXII-IN-5；化合物 hCAXII-IN-5hCAXII-IN-5
hCAXII-IN-5 (compound 6o) is a highly effective and specific inhibitor of hCAXII. The compound exhibits impressive binding affinities, with Ki values of >10000, >10000, 286.1, and 1.0 nM for hCAI, hCAII, hCAIX, and hCAXII, respectively [1].
价 格：￥电议型 号：T61769产 地：中国大陆
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T6175ADL-5859；化合物ADL5859 HClADL5859 Hydrochloride|||ADL5859 HCl；ADL5859 Hydrochloride|||ADL5859 HCl
ADL-5859 (ADL5859 Hydrochloride) is a selective δ-opioid receptor agonist ( Ki: 0.8 nM), selectivity against opioid receptor κ, μ, and little inhibition for the hERG channel.
价 格：￥电议型 号：T6175产 地：中国大陆
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T61745hCAI/II-IN-6；化合物hCAI/II-IN-6hCAI/II-IN-6
hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA). hCAI/II-IN-6 inhibited hCA I, hCA II, hCA VII, and hCA XII with Ki values of 220, 4.9, 6.5, and ＞50,000 nM. hCAI/II-IN-6 showed anticonvulsant activity in vivo. hCAI/II-IN-6 can be used to study epilepsy. hCAI/II-IN-6 showed anticonvulsant activity in vivo. hCAI/II-IN-6 can be used to study epilepsy.
价 格：￥电议型 号：T61745产 地：中国大陆
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T61635hCAI/II-IN-4；化合物 hCAI/II-IN-4hCAI/II-IN-4
hCAI/II-IN-4 (compound 6d) is a powerful inhibitor of both hCA I and hCA II enzymes, with Ki values of 16.95 nM and 15.22 nM, respectively. It demonstrates inhibitory activity against hCA IX with a Ki value of 27.04 nM. Additionally, hCAI/II-IN-4 exhibits anti-hypoxia properties while maintaining low toxicity. This compound is suitable for investigating acute mountain sickness (AMS) in research studies [1].
价 格：￥电议型 号：T61635产 地：中国大陆
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T6162BS-181 hydrochloride；化合物BS-181 HClBS-181 HCl；BS-181 HCl
BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
价 格：￥电议型 号：T6162产 地：中国大陆
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T61617Hcyb1；化合物 Hcyb1Hcyb1
Hcyb1 is a potent and specific inhibitor of phosphodiesterase 2 (PDE2). It exhibits a high degree of selectivity for inhibiting PDE2A with an IC50 value of 0.57 μM. In addition, Hcyb1 displays over 250-fold selectivity against other recombinant members of the PDE family. Moreover, its pharmacological actions include neuroprotective and antidepressant-like effects, which are believed to be mediated through the cAMP/cGMP-CREB-BDNF signaling pathway [1].
价 格：￥电议型 号：T61617产 地：中国大陆
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T6161Tubastatin A Hydrochloride；化合物Tubastatin A HClTSA HCl|||Tubastatin A HCl；TSA HCl|||Tubastatin A HCl
Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM). It has selectivity (>1000-fold) against all other isozymes except HDAC8 (>57-fold).
价 格：￥电议型 号：T6161产 地：中国大陆
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T6158LDN-193189 HCl；化合物LDN-193189 HClLDN193189 Hydrochloride；LDN193189 Hydrochloride
LDN-193189 HCl (LDN193189 Hydrochloride) is a selective BMP type I receptor kinases inhibitor.
价 格：￥电议型 号：T6158产 地：中国大陆
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T6155Almorexant hydrochloride；化合物Almorexant HClACT-078573 hydrochloride|||Almorexant HCl；ACT-078573 hydro
Almorexant hydrochloride (ACT-078573 hydrochloride) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
价 格：￥电议型 号：T6155产 地：中国大陆
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T6148CX-6258 hydrochloride；化合物CX-6258 HClCX-6258 HCl|||Pim-Kinase Inhibitor X；CX-6258 HCl|||Pim-Kinase In
CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).
价 格：￥电议型 号：T6148产 地：中国大陆
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T6146Dorsomorphin dihydrochloride；化合物Dorsomorphin dihydrochlorideBML-275 2HCl|||Compound C dihydrochlorid
Dorsomorphin dihydrochloride (BML-275 2HCl) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin dihydrochloride inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride induces autophagy, and possesses antitumor activity.
价 格：￥电议型 号：T6146产 地：中国大陆
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T6145ZM39923 hydrochloride化合物ZM 39923 HClJAK3 Inhibitor IV|||ZM 39923 HCl
ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
价 格：￥电议型 号：T6145产 地：中国大陆
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T6142PD128907 HCl；化合物PD128907盐酸盐PD128907 HCl
PD128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor.
价 格：￥电议型 号：T6142产 地：中国大陆
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T6139LA-674563 2HCl(552325-73-2(fb-2hcl))；化合物A-674563 2HClA-674563 2HCl(552325-73-2(fb-2hcl))
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
价 格：￥电议型 号：T6139L产 地：中国大陆
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T61384hCAIX/XII-IN-4；化合物 hCAIX/XII-IN-4hCAIX/XII-IN-4
hCAIX/XII-IN-4 (compound 6c) is a highly potent inhibitor of CAIX/XII. It exhibits Ki values of 4.5 nM, 23.6 nM, >10000 nM, and >10000 nM for CAXII, CAIX, CAI, and CAⅡ, respectively [1].
价 格：￥电议型 号：T61384产 地：中国大陆
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T61338MS023 dihydrochloride；MS023 盐酸盐MS023 2HCl；MS023 2HCl
MS023 dihydrochloride (MS023 2HCl) is a selective, cytosolic and highly potent inhibitor of human type I protein arginine methyltransferases (PRMTs) with antitumour activity, inhibits PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, and increases the proliferative capacity of isolated cultured MuSC. It can be used to study breast cancer.
价 格：￥电议型 号：T61338产 地：中国大陆
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T61334DMA-135 hydrochloride；DMA-135 盐酸盐DMA-135 HCl；DMA-135 HCl
DMA-135 hydrochloride (DMA-135 HCl) Antivirally active compounds that target RNA and inhibit enterovirus type 71 (EV71) IRES-dependent translation and replication.DMA-135 hydrochloride can be used in the study of enteroviral infections.
价 格：￥电议型 号：T61334产 地：中国大陆
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T61282hCAI/II-IN-2；化合物 hCAI/II-IN-2hCAI/II-IN-2
hCAI/II-IN-2 (compound 2b) is a highly effective dual inhibitor of human carbonic anhydrase I and II (hCA I/II), with Ki values of 40.97 nM, 15.15 nM, and 61.88 nM for hCA I, hCA II, and hCA IX, respectively. With its anti-hypoxic properties, hCAI/II-IN-2 demonstrates activity against acute mountain sickness (AMS). Furthermore, this compound exhibits low cellular activity [1].
价 格：￥电议型 号：T61282产 地：中国大陆
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T61263hCA IX-IN-1；化合物 hCA IX-IN-1hCA IX-IN-1
hCA IX-IN-1 (Compound 6f) is a human carbonic anhydrase ( hCA ) inhibitor with K i values of 331.4, 28.4, 9.4 and 17.8 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-1 shows anticancer activity [1].
价 格：￥电议型 号：T61263产 地：中国大陆
