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T6294NVP-BSK805 2HCl (1092499-93-8(free base));化合物NVP-BSK805 2HClNVP-BSK805 dihydrochloride|||BSK 805|||N
NVP-BSK805 2HCl (1092499-93-8(free base)) (BSK 805)(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.
价 格:¥电议型 号:T6294产 地:中国大陆
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T62892hCAI/II-IN-1;化合物 hCAI/II-IN-1hCAI/II-IN-1
hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).
价 格:¥电议型 号:T62892产 地:中国大陆
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T6279LGivinostat hydrochloride;化合物Givinostat hydrochlorideITF2357 hydrochloride|||Givinostat HCl|||ITF2357
Givinostat hydrochloride (ITF2357 hydrochloride) is an inhibitor of HDAC with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat hydrochloride exhibits anti-inflammatory, anti-angiogenic, and antineoplastic activities.
价 格:¥电议型 号:T6279L产 地:中国大陆
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T62755HCAIX-IN-2;化合物 HCAIX-IN-2HCAIX-IN-2
HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).
价 格:¥电议型 号:T62755产 地:中国大陆
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T6268Ceftiofur hydrochloride;头孢噻呋盐酸盐Ceftiofur HCl|||U-67279A|||Excenel hydrochloride;头孢噻呋盐酸盐|||Ceftiofur
Ceftiofur hydrochloride (U-67279A) is the hydrochloride salt form of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity.
价 格:¥电议型 号:T6268产 地:中国大陆
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T6250H-89 dihydrochloride;化合物H 89 2HClProtein kinase inhibitor H-89 dihydrochloride|||H 89 2HCl|||5-Isoqu
H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).
价 格:¥电议型 号:T6250产 地:中国大陆
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T62380L20-HC-Me-Pyrrolidine FA;20-HC-Me-Pyrrolidine甲酸盐20-HC-Me-Pyrrolidine FA
20-HC-Me-Pyrrolidine FA is a potent inhibitor of Aster proteins, inhibiting Aster-A, Aster-B, and Aster-C, and inhibiting Aster protein binding and transfer of cholesterol.20-HC-Me-Pyrrolidine FA can be used in studies of lipid metabolism.20-HC-Me-Pyrrolidine FA is a potent inhibitor of Aster proteins.
价 格:¥电议型 号:T62380L产 地:中国大陆
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T6238020-HC-Me-Pyrrolidine;化合物 20-HC-Me-Pyrrolidine20-HC-Me-Pyrrolidine
20-HC-Me-Pyrrolidine was A potent inhibitor of Aster protein, with IC50 values of 0.11 μM, 0.06 μM and 0.71 μM for Aster A, Aster B and Aster C, respectively. 20-HC-Me-Pyrrolidine prevents Aster protein from binding and transferring cholesterol and inhibits the movement of low-density lipoprotein (LDL) cholesterol into the endoplasmic reticulum (ER).
价 格:¥电议型 号:T62380产 地:中国大陆
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T62356Mardepodect hydrochloride;Mardepodect 盐酸盐PF-2545920 HCl|||Mardepodect HCl|||MP-10 HCl|||PF-02545920
Mardepodect hydrochloride (Mardepodect HCl) is an orally active, selective and potent inhibitor of PDE10A that crosses the blood-brain barrier (IC50: 0.37 nM).Mardepodect hydrochloride up-regulates the expression of proteins encoding specific growth and transcription factors, cell signalling molecules and cell surface proteins. Mardepodect hydrochloride upregulates genes encoding specific growth factors, transcription factors, cell signalling molecules, and cell surface proteins, while downregul
价 格:¥电议型 号:T62356产 地:中国大陆
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T6234Ambroxol hydrochloride;盐酸氨溴索Mucosolvan|||Mucoangin|||Ambroxol HCl;Mucosolvan|||Mucoangin|||盐酸氨溴索|||A
Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
价 格:¥电议型 号:T6234产 地:中国大陆
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T6232Vilazodone Hydrochloride;盐酸维拉佐酮SB659746A|||EMD 68843|||Vilazodone HCl;盐酸维拉佐酮|||SB659746A|||EMD 68843
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder.
价 格:¥电议型 号:T6232产 地:中国大陆
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T6227Benidipine hydrochloride;盐酸贝尼地平(±)-Benidipine|||Benidipine HCl|||KW-3049|||Coniel;(±)-Benidipine|||B
Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.
价 格:¥电议型 号:T6227产 地:中国大陆
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T6225Adenine hydrochloride;腺嘌呤盐酸盐Adenine HCl|||6-Aminopurine hydrochloride;Adenine HCl|||腺嘌呤盐酸盐|||6-Amino
Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.
价 格:¥电议型 号:T6225产 地:中国大陆
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T62101hCAXII-IN-2;化合物 hCAXII-IN-2hCAXII-IN-2
hCAXII-IN-2 (compound 5i) is a potent inhibitor of human carbonic anhydrase XII (hCA XII) (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity against hCA I and hCA II.
价 格:¥电议型 号:T62101产 地:中国大陆
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T6203LSaxagliptin hydrochloride化合物 T6203LBMS477118|||Saxagliptin|||BMS 477118|||Saxagliptin HCl|||BMS-4771
Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in patients with type 2 diabetes mellitus.
价 格:¥电议型 号:T6203L产 地:中国大陆
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T62026hCAIX-IN-11;化合物 hCAIX-IN-11hCAIX-IN-11
hCAIX-IN-11 (Compound 5d) is a selective carbonic anhydrase IX and XII inhibitor. hCAIX-IN-11 shows K i s of 32.7 and 623.5 nM for hCA IX and hCA XII, respectively.
价 格:¥电议型 号:T62026产 地:中国大陆
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T61959hCAIX/XII-IN-3;化合物 hCAIX/XII-IN-3hCAIX/XII-IN-3
hCAIX/XII-IN-3 (compound 6q) is a potent, selective inhibitor of hCAIX and hCAXII. hCAIX/XII-IN-3 shows K i values of >10000, >10000, 66.2, 4.4 nM for hCAI, hCAII, hCAIX and hCAXII, respectively .
价 格:¥电议型 号:T61959产 地:中国大陆
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T61896hCAIX-IN-12;化合物 hCAIX-IN-12hCAIX-IN-12
hCAIX-IN-12 is an effective hCAIX inhibitor, IC50 for CAIX and CAII is 0.74 and 10.78 μM , respectively. hCAIX-IN-12 inhibits cell proliferation and induces apoptosis. HCAIX-IN-12 can increase the generation of ROS. HCAIX-IN-12 has research potential in colorectal cancer (CRC).
价 格:¥电议型 号:T61896产 地:中国大陆
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T61873hCAIX/XII-IN-1;化合物 hCAIX/XII-IN-1hCAIX/XII-IN-1
hCAIX/XII-IN-1, a potent inhibitor of both CAIX and CAXII, exhibits KI values of 0.48 μM for CAIX and 0.83 μM for CAXII, respectively. This compound demonstrates antiproliferative activity in vitro and induces apoptosis in MCF-7 cells [1].
价 格:¥电议型 号:T61873产 地:中国大陆
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T61852hCAIX-IN-8;化合物 hCAIX-IN-8hCAIX-IN-8
hCAIX-IN-8 (compound 7i) is a highly potent and selective inhibitor of hCAIX, demonstrating potent inhibitory activity against CAIX with an IC50 value of 0.024 μM. It also exhibits inhibitory activity against CAII and CAVA with IC50 values of 1.99 μM and 1.10 μM, respectively. Furthermore, hCAIX-IN-8 exhibits anti-proliferative effects and low toxicity. It effectively reduces the occurrence of epithelial-to-mesenchymal transitions and promotes apoptosis. Additionally, hCAIX-IN-8 effectively inhi
价 格:¥电议型 号:T61852产 地:中国大陆