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T17315(±)-CPSI-1306;化合物cpsi-1306cpsi-1306|||2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholi
(±)-CPSI-1306 (2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) is a macrophage migration inhibitory factor (MIF) antagonist and can be used in studies about non-insulin-dependent diabetes mellitus (NIDDM) and the prevention of the deleterious cutaneous effects of acute and chronic UVB exposure.
价 格:¥电议型 号:T17315产 地:中国大陆
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T17262XE 991 dihydrochloride;化合物XE 991 dihydrochlorideXE 991 dihydrochloride
XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively).
价 格:¥电议型 号:T17262产 地:中国大陆
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T1725Y-27632 dihydrochloride;化合物Y-27632 dihydrochlorideY-27632 2HCl;反式-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.
价 格:¥电议型 号:T1725产 地:中国大陆
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T17068TH1834 dihydrochloride;化合物 T17068TH1834 dihydrochloride
TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor. TH1834 dihydrochloride causes apoptosis and enhances DNA damage in breast cancer.
价 格:¥电议型 号:T17068产 地:中国大陆
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T16855SB-772077B dihydrochloride;化合物 T16855SB-772077B dihydrochloride
SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).
价 格:¥电议型 号:T16855产 地:中国大陆
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T16527Phytic acid dodecasodium salt hydrate;植酸十二钠盐myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium
Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate inhibits the enzymatic superoxide source xanthine oxidase with an IC50 of 6 mM and has antioxidative, neuroprotective, and anti-inflammatory effects.
价 格:¥电议型 号:T16527产 地:中国大陆
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T16524Philanthotoxin 74 dihydrochloride;化合物Philanthotoxin 74 盐酸盐PhTx-74 HCl|||PhTx 74 dihydrochloride;PhTx
Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.
价 格:¥电议型 号:T16524产 地:中国大陆
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T16443PCS1055 dihydrochloride;化合物 T16443PCS1055 dihydrochloride
PCS1055 dihydrochloride is an effective, selective, and competitive muscarinic M4 receptor antagonist (IC50: 18.1 nM and a Kd: 5.72 nM). PCS1055 dihydrochloride is also a potent AChE inhibitor (IC50 s: 22 nM and 120 nM for electric eel and human AChE, respectively). PCS1055 dihydrochloride inhibits radioligand [3H]-NMS binding to the M4 receptor (Ki: 6.5 nM). PCS1055 dihydrochloride shows >100-fold selectivity over M1-, M3-, and M5-receptors and 30-fold selectivity at the M2 receptor.
价 格:¥电议型 号:T16443产 地:中国大陆
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T1616Cefotiam hydrochloride;盐酸头孢替安Pansporin|||SCE-963 hydrochloride|||Pansporine|||Cefotiam dihydrochlori
Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
价 格:¥电议型 号:T1616产 地:中国大陆
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T15808Merestinib dihydrochloride化合物 T15808LY2801653 dihydrochloride
Merestinib dihydrochloride is an effective and orally bioavailable c-Met inhibitor (Ki=2 nM). It has anti-tumor activities and also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM).
价 格:¥电议型 号:T15808产 地:中国大陆
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T15746Lexibulin dihydrochloride;化合物 T15746CYT-997 dihydrochloride;CYT-997 dihydrochloride
Lexibulin 2Hcl is an effective tubulin polymerization inhibitor (IC50: 10-100 nM in cancer cell lines). It also has potent cytotoxic and vascular disrupting activity in vitro and in vivo.
价 格:¥电议型 号:T15746产 地:中国大陆
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T15674Tirbanibulin dihydrochloride化合物 T15674KX-01 (dihydrochloride)|||KX2-391 (dihydrochloride)
Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).
价 格:¥电议型 号:T15674产 地:中国大陆
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T15590Iodophenpropit dihydrobromide;化合物 T15590Iodophenpropit dihydrobromide
Iodophenpropit dihydrobromide is an effective and selective antagonist of the histamine H3 receptor. The binding of [125I]Iodophenpropit is readily reversible, selective, and of high affinity (KD: 0.32 nM).
价 格:¥电议型 号:T15590产 地:中国大陆
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T15580Inolitazone dihydrochloride化合物 T15580RS5444 dihydrochloride|||CS-7017 dihydrochloride|||Efatutazone
Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth. Inolitazone dihydrochloride enhances the role of cell cycle kinase inhibitor p21 WAF1/CIP1.
价 格:¥电议型 号:T15580产 地:中国大陆
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T15565Imetit dihydrobromide化合物 T15565VUF 8325 dihydrobromide|||SKF 91105 dihydrobromide
Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).
价 格:¥电议型 号:T15565产 地:中国大陆
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T1542Pirenzepine dihydrochloride;盐酸哌仑西平Pirenzepine HCl|||Bisvanil|||Tabe|||LS519;Pirenzepine HCl|||Bisvan
Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion.
价 格:¥电议型 号:T1542产 地:中国大陆
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T1541Drospirenone;屈螺酮ZK 3059|||Dihydrospirorenone;ZK 3059|||屈螺酮|||Dihydrospirorenone
Drospirenone (ZK 3059) is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
价 格:¥电议型 号:T1541产 地:中国大陆
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T15396GN44028;化合物GN44028N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine;N-(2,
GN44028 (N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine) is a hypoxia-inducible factor inhibitor of (HIF)-1 (IC50: 14 nM). GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity. However, It can not be suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization.
价 格:¥电议型 号:T15396产 地:中国大陆
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T15394Glyceryl monocaprate;一癸酸甘油酯2,3-Dihydroxypropyl decanoate|||DECANOIN|||Monocaprin;2,3-Dihydroxypropyl
Glyceryl monocaprate (2,3-Dihydroxypropyl decanoate) has inhibitory effect on Herpes Simplex Virus (HSV). It also offers an effective treatment for herpes labialiss. Glyceryl monocaprate is a capric acid against 1-monoglyceride gram-positive bacterial infections.
价 格:¥电议型 号:T15394产 地:中国大陆
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T15206Eldecalcitol;艾地骨化醇ED-71|||2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3;艾地骨化醇|||ED-71|||2-(3-hydroxy
Eldecalcitol possesses a potent inhibitory effect on bone resorption and induces a significant increase in bone mineral density. Eldecalcitol is an orally active analogue of active vitamin D. It also is used in the treatment of osteoporosis .
价 格:¥电议型 号:T15206产 地:中国大陆