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T15130Dilazep dihydrochloride;地拉卓二盐酸盐Dilazep dihydrochloride
Dilazep dihydrochloride is an adenosine uptake inhibitor. Dilazep dihydrochloride also inhibits the ischemic damage, membrane transport of nucleosides and platelet aggregation. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine.
价 格:¥电议型 号:T15130产 地:中国大陆
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T15128Dihydrofolic acid;二氢叶酸7,8-Dihydrofolic acid|||Dihydrofolate;7,8-Dihydrofolic acid|||Dihydrofolate
Dihydrofolic acid (7,8-Dihydrofolic acid) is a folic acid derivative that produces tetrahydrofolic acid in the presence of dihydrofolic acid reductase.
价 格:¥电议型 号:T15128产 地:中国大陆
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T15112Dianicline dihydrochloride;化合物 T15112Dianicline dihydrochloride
Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.
价 格:¥电议型 号:T15112产 地:中国大陆
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T14998Copanlisib dihydrochloride;库潘尼西盐酸BAY 80-6946 dihydrochloride;库潘尼西盐酸|||BAY 80-6946 dihydrochloride
Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor (IC50s: 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ). Copanlisib dihydrochloride has superior antitumor activity and it also has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR.
价 格:¥电议型 号:T14998产 地:中国大陆
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T14941CGP37157;CGP371577-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one;7-Chloro-5-(2
CGP37157 (7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one) is a Na+/Ca2+ exchanger inhibitor, inhibits Na+-induced Ca2+ release from mitochondria in guinea pig heart with IC50 of 0.8 μM.
价 格:¥电议型 号:T14941产 地:中国大陆
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T1476LPramipexole dihydrochloride;盐酸普拉克索Pramipexole dihydrochloride
Pramipexole dihydrochloride could be used to treat Parkinson disease.
价 格:¥电议型 号:T1476L产 地:中国大陆
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T14490Talipexole dihydrochloride;盐酸他利克索Domnin|||B-HT 920 dihydrochloride;Domnin|||盐酸他利克索|||B-HT 920 dihydr
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, respectively. It displays antiParkinsonian activity.
价 格:¥电议型 号:T14490产 地:中国大陆
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T14366AZ10606120 dihydrochloride;化合物AZ10606120 dihydrochlorideAZ10606120 dihydrochloride
AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and has anti-angiogenic activity. AZ 10606120 acts as a negative allosteric modulator when bound to a site coupled to the ATP binding site.
价 格:¥电议型 号:T14366产 地:中国大陆
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T14362LAY 9944 dihydrochloride;化合物AY 9944 盐酸盐AY 9944 dihydrochloride
AY 9944 dihydrochloride is a intermediate.
价 格:¥电议型 号:T14362L产 地:中国大陆
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T14177Alexidine dihydrochloride;己联双辛胍二盐酸盐Alexidine dihydrochloride
Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens. Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1, in mammalian cells and causes mitochondrial apoptosis. Thus, Alexidine dihydrochloride has the potential to be developed as a pan-antifungal, antibiofilm drug.
价 格:¥电议型 号:T14177产 地:中国大陆
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T140637α,25-Dihydroxycholesterol;7α,25-OHC7α,25-OHC;7α,25-OHC
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2], and it is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM).
价 格:¥电议型 号:T14063产 地:中国大陆
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T140363’,4’-Dihydroxyflavonol;化合物 T14036DiOHF;DiOHF
3´,4´-Dihydroxyflavonol (DiOHF) is an efficient antioxidant that diminishes superoxide levels and enhances nitric oxide (NO) functionality in the mesenteric arteries of diabetic rats[1].
价 格:¥电议型 号:T14036产 地:中国大陆
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T13978(S)-3,4-Dihydroxybutyric acid;化合物 T13978(S)-3,4-Dihydroxybutyric acid
(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.
价 格:¥电议型 号:T13978产 地:中国大陆
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T13890SMARCA-BD ligand 1 for Protac dihydrochloride;化合物T13890SMARCA-BD ligand 1 for Protac dihydrochloride
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
价 格:¥电议型 号:T13890产 地:中国大陆
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T13759LTX-401 dihydrochloride (1262851-70-6 free base);化合物 T13759LTX-401 dihydrochloride;LTX-401 dihydroch
LTX-401, targets the Golgi apparatus, and is an oncolytic amino acid derivative.
价 格:¥电议型 号:T13759产 地:中国大陆
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T1368Methyl 3,4-dihydroxybenzoate;3,4-二羟基苯甲酸甲酯3,4-Dihydroxybenzoic acid methyl ester|||Methyl protocatech
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect.
价 格:¥电议型 号:T1368产 地:中国大陆
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T13675Elacestrant dihydrochloride;化合物RAD1901 dihydrochlorideRAD1901 dihydrochloride;RAD1901 dihydrochlorid
Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader with IC50s of 48 for ERα and 870 nM for ERβ, respectively.
价 格:¥电议型 号:T13675产 地:中国大陆
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T13671L(S,R,S)-AHPC-Me dihydrochloride;化合物 T13671LVHL ligand 2 dihydrochloride|||E3 ligase Ligand 1 dihydro
(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demonstrates potent degradation of BET protein in castration-resistant prostate cancer (CRPC) cells, with a DC50 of less than 1 nM. This compound serves as the VHL ligand, specifically the (S,R,S)-AHPC-based VHL ligand, that facilitates the recruitment of von Hippel-Lindau (VHL) prote
价 格:¥电议型 号:T13671L产 地:中国大陆
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T13653Dihydrocephalomannine;紫杉醇EP杂质RDihydrocephalomannine
Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.
价 格:¥电议型 号:T13653产 地:中国大陆
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T13632D-Erythro-dihydrosphingosine;D-赤式-C 18 - 二氢-D-神经鞘氨醇Dihydrosphingosine|||Octadecasphinganine|||C18-Di
D-Erythro-dihydrosphingosine (C18-Dihydrosphingosine) inhibits arachidonic acid release and cPLA2α activity.
价 格:¥电议型 号:T13632产 地:中国大陆