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T80637Homatropine hydrochloride;盐酸后马托品Homatropine hydrochloride
Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussive properties. It is utilized in research pertaining to ocular diseases and coughs [1].
价 格:¥电议型 号:T80637产 地:中国大陆
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T80636SARS-CoV-2-IN-59;4-(4,5-二氢-2-咪唑基)苯腈SARS-CoV-2-IN-59
SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule that inhibits SARS-CoV-2 by targeting its main protease (Mpro). It exhibits robust binding with Mpro residues (Met 165, Gln 166, Met 165, His 41, Gln 189) [1].
价 格:¥电议型 号:T80636产 地:中国大陆
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T80635Gentisuric acid;化合物 Gentisuric acidGentisuric acid
Gentisuric acid, an Aspirin metabolite and a substrate of α-amidating monooxygenase (PAM), mitigates DNA damage induced by Mitomycin C. [1] [2]
价 格:¥电议型 号:T80635产 地:中国大陆
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T80634MAO-B-IN-19;化合物 MAO-B-IN-19MAO-B-IN-19
MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].
价 格:¥电议型 号:T80634产 地:中国大陆
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T80633Androgen receptor degrader-1;化合物 Androgen receptor degrader-1Androgen receptor degrader-1
Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].
价 格:¥电议型 号:T80633产 地:中国大陆
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T80632Methyl 3,4-dimethoxycinnamate;3,4-二甲氧基肉桂酸甲酯Methyl 3,4-dimethoxycinnamate
Methyl 3,4-dimethoxycinnamate impedes uredospore germination and concurrently inhibits global DNA methylation in Hep3B cells [1] [2].
价 格:¥电议型 号:T80632产 地:中国大陆
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T80631Esculin sesquihydrate;化合物 Esculin sesquihydrateEsculin sesquihydrate
Esculin sesquihydrate, a coumarin glucoside with fluorescent properties and a constituent of ash bark, improves cognitive deficits associated with experimental diabetic nephropathy (DN). It also offers anti-oxidative and anti-inflammatory benefits through the MAPK signaling pathway [1] [2].
价 格:¥电议型 号:T80631产 地:中国大陆
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T80630H-Arg-OtBu dihydrochloride;化合物 H-Arg-OtBu dihydrochlorideH-Arg-OtBu dihydrochloride
H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial that engages the negatively charged bacterial membrane through electrostatic and hydrophobic interactions, with applications in bacterial infection disease research [1].
价 格:¥电议型 号:T80630产 地:中国大陆
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T8063Cephapirin Benzathine;苄星头孢匹林Cephapirin Benzathine
Cephapirin Benzathine is a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity.
价 格:¥电议型 号:T8063产 地:中国大陆
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T80063Imperatoxin A;欧前胡素 AImperatoxin A
Imperatoxin A, a peptide toxin sourced from the African scorpion Pandinus imperator, functions as an activator of Ca2+-release channels/ryanodine receptors (RyRs), facilitating increased Ca2+ flow from the sarcoplasmic reticulum into the cell [1].
价 格:¥电议型 号:T80063产 地:中国大陆
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T79063IRE1α kinase-IN-9;化合物 IRE1α kinase-IN-9IRE1α kinase-IN-9
IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM. It is suitable for research into diseases linked to the unfolded protein response or regulated IRE1-dependent decay (RIDD) [1].
价 格:¥电议型 号:T79063产 地:中国大陆
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T78063Endothelin-1 (1-31) (Human) TFA;化合物 Endothelin-1 (1-31) (Human) TFAEndothelin-1 (1-31) (Human) TFA
Endothelin-1 (1-31) (Human) TFA, a potent vasoconstrictor and hypertensive agent, originates from the chymase-mediated selective hydrolysis of big ET-1 [1].
价 格:¥电议型 号:T78063产 地:中国大陆
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T77063Libivirumab;化合物 LibivirumabLibivirumab
Libivirumab (17.1.41), a humanized monoclonal antibody targeting hepatitis B virus (HBV), demonstrates neutralizing activity with half maximal inhibitory concentrations (IC50) of 35 ng/mL for HBsAg and 130 ng/mL for HBeAg, respectively [1].
价 格:¥电议型 号:T77063产 地:中国大陆
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T76063LBeta-defensin 1, pig TFA;化合物 Beta-defensin 1, pig TFABeta-defensin 1, pig TFA
Beta-defensin 1, pig TFA, an antimicrobial peptide predominantly located in the tongue mucosa of pigs, exhibits activity against a diverse range of bacteria including Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis, and the fungus Candida albicans [1] [2].
价 格:¥电议型 号:T76063L产 地:中国大陆
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T76063Beta-defensin 1, pig;化合物 Beta-defensin 1, pigBeta-defensin 1, pig
Beta-defensin 1, pig, is an antimicrobial peptide predominantly located in the tongue mucosa of pigs. It exhibits activity against a variety of bacteria including Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis, and the fungus Candida albicans [1] [2].
价 格:¥电议型 号:T76063产 地:中国大陆
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T75063N1-Methyl-3’-O-(2-methoxyethyl) adenosine;化合物 N1-Methyl-3’-O-(2-methoxyethyl) adenosineN1-Methyl-3’-
N1-Methyl-3’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis [1].
价 格:¥电议型 号:T75063产 地:中国大陆
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T7488BD1063 dhydrochloride;化合物BD1063BD1063;BD1063
BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
价 格:¥电议型 号:T7488产 地:中国大陆
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T74561JBJ-09-063 TFA;化合物 JBJ-09-063 TFAJBJ-09-063 TFA
JBJ-09-063 TFA is a mutant-selective allosteric EGFR inhibitor, displaying IC50 values of 0.147 nM for EGFR L858R, 0.063 nM for EGFR L858R/T790M, 0.083 nM for EGFR L858R/T790M/C797S, and 0.396 nM for EGFR L747S mutations. It effectively reduces phosphorylation of EGFR, Akt, and ERK1/2, demonstrating efficacy in models sensitive and resistant to EGFR tyrosine kinase inhibitors (TKI). JBJ-09-063 TFA holds potential for research in EGFR-mutant lung cancer [1].
价 格:¥电议型 号:T74561产 地:中国大陆
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T74063MeCY5-NHS ester triethylamine;化合物 MeCY5-NHS ester triethylamineMeCY5-NHS ester triethylamine
MeCY5-NHS ester (potassium) is a reactive dye optimized for labeling proteins and nucleic acids [1].
价 格:¥电议型 号:T74063产 地:中国大陆
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T73445TIM-063;化合物 TIM-063TIM-063
TIM-063 is a selective, cell-permeable inhibitor of CaMKK that competes with ATP, directly targeting the catalytic domain of CaMKK. It exhibits K(i) values of 0.35 μM for CaMKKα and 0.2 μM for CaMKKβ, with respective IC(50) values of 0.63 μM and 0.96 μM.
价 格:¥电议型 号:T73445产 地:中国大陆