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T77332TV 3279;化合物TV 3279TV 3279
TV 3279 is a novel ChE-MAI inhibitor , and the neuroprotective properties depend on their ability to induce the anti-apoptotic proteins PKC, Bcl-2, Bcl-x, and SOD, and to block the nuclear translocation of the pro-apoptotic enzyme glyceraldehyde phosphate dehydrogenase in PC-12 and neuroblastoma cells.
价 格:¥电议型 号:T77332产 地:中国大陆
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T76327CTCE-0214;化合物 CTCE-0214CTCE-0214
CTCE-0214, a chemokine CXC receptor 4 (CXCR4) agonist and SDF-1α (stromal cell-derived factor-1α) peptide analog, exhibits anti-inflammatory properties. It is applicable in the research of inflammation, sepsis, and systemic inflammatory syndromes [1] [2] [3].
价 格:¥电议型 号:T76327产 地:中国大陆
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T75327Magnesium silicate;化合物 Magnesium silicateMagnesium silicate
Activated Magnesium Silicate, a blend of magnesium oxide (MgO) and silicon dioxide (SiO2), serves multiple roles in healthcare and industrial applications, including as an antacid, antiulcer agent, deodorizer, decolorizer, and antifungal treatment [1].
价 格:¥电议型 号:T75327产 地:中国大陆
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T74327Antitumor agent-41;化合物 Antitumor agent-41Antitumor agent-41
Antitumor Agent-41 (Compound N-12) exhibits potent antitumor properties, demonstrating significant antimigration and anti-invasion activities. It induces tumor inhibition through tumor necrosis and inflammatory response [1].
价 格:¥电议型 号:T74327产 地:中国大陆
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T73327Merigolix;化合物 MerigolixMerigolix
Merigolix is a potent gonadotrophin releasing hormone (GnRH) antagonist [1] .
价 格:¥电议型 号:T73327产 地:中国大陆
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T73279MLKL-IN-5;化合物 MLKL-IN-5MLKL-IN-5
MLKL-IN-5 is a potent MLKL inhibitor that mediates necroptosis [1] .
价 格:¥电议型 号:T73279产 地:中国大陆
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T73277FABP-IN-2;化合物 FABP-IN-2FABP-IN-2
FABP-IN-2, a novel ligand for FABP3, demonstrates inhibition of both FABP3 and FABP4 with IC50 values of 1.16 μM and 4.27 μM, respectively.
价 格:¥电议型 号:T73277产 地:中国大陆
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T73276BTK-IN-23;化合物 BTK-IN-23BTK-IN-23
BTK-IN-23 is a BTK inhibitor with an IC50 value of 12.8 nM, demonstrating kinase selectivity superior to Ibrutinib [1]. It also effectively inhibits BLX and BMX, with IC50 values of 35.6 nM and 5.7 nM, respectively.
价 格:¥电议型 号:T73276产 地:中国大陆
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T73275BTK-IN-22;化合物 BTK-IN-22BTK-IN-22
BTK-IN-22, a BTK inhibitor (IC 50: 0.9 nM), also exhibits inhibition against BLX and BMX with IC 50 values of 1.4 and 1.2 nM, respectively. Demonstrating enhanced kinase selectivity, BTK-IN-22 outperforms Ibrutinib in this regard [1].
价 格:¥电议型 号:T73275产 地:中国大陆
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T73274CamA-IN-1;CamA-IN-1CamA-IN-1
CamA-IN-1 is a Clostridioides difficile -specific DNA adenine methyltransferase (CamA) inhibitor. CamA-IN-1 has inhibitory for CamA with IC 50 and K d values of 0.4 μM and 0.2 μM, respectively. CamA-IN-1 can be used for the research of Clostridioides difficile infections (CDI) [1] .
价 格:¥电议型 号:T73274产 地:中国大陆
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T73273SERT-IN-2;化合物 SERT-IN-2SERT-IN-2
SERT-IN-2, a potent SERT inhibitor (IC 50 = 0.58 nM), exhibits promising efficacy as an anti-depressant. It demonstrates a favorable bioavailability of 83.28% in rats and has the ability to cross the blood-brain barrier.
价 格:¥电议型 号:T73273产 地:中国大陆
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T73272VU6019650;VU6019650VU6019650
VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR ( IC 50 =36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopaminergic reward circuitry. VU6019650 blocks Oxotremorine M iodide induced increases of neuronal firing rates of midbrain dopamine neurons in the ventral tegmental area (VTA) [1] [2] .
价 格:¥电议型 号:T73272产 地:中国大陆
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T73271MMV688845;化合物 MMV688845(R)-GSK1729177A;(R)-GSK1729177A
MMV688845 is a bactericidal nontuberculous mycobacteria (NTM) RNA polymerase inhibitor that exhibits anti-tuberculosis efficacy and is effective against Mycobacterium abscessus.
价 格:¥电议型 号:T73271产 地:中国大陆
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T73270GSK3-IN-2;GSK3抑制剂2GSK3-IN-2
GSK3-IN-2 is a potent GSK3 inhibitor [1] .
价 格:¥电议型 号:T73270产 地:中国大陆
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T73277-Methoxyisoflavone;7-甲氧基异黄酮7-Methoxyisoflavone
7-Methoxyisoflavone is an activator of adenosine monophosphate-activated protein kinase (AMPK).
价 格:¥电议型 号:T7327产 地:中国大陆
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T71854AA43279;化合物 AA43279AA43279
AA43279 is a novel selective Nav1.1 activator, increasing the firing activity of parvalbumin-expressing, fast-spiking GABAergic interneurons and increasing the spontaneous inhibitory post-synaptic currents (sIPSCs) recorded from pyramidal neurons.
价 格:¥电议型 号:T71854产 地:中国大陆
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T71327Paraxanthine-d6;化合物 Paraxanthine-d6Paraxanthine-d6
Paraxanthine-d6 is intended for use as an internal standard for the quantification of paraxanthine by GC- or LC-MS. Paraxanthine is an active metabolite of caffeine. It is formed via N3-demethylation of caffeine by the cytochrome P450 (CYP) isoform CYP1A2. Paraxanthine is an adenosine A1 and A2 receptor antagonist. In vivo, paraxanthine increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by the adenosine A1 agoni
价 格:¥电议型 号:T71327产 地:中国大陆
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T71007AZD-2327 sesquifumarate;化合物 AZD-2327 sesquifumarateAZD-2327 sesquifumarate
AZD-2327 sesquifumarate is a delta opioid receptor agonist.
价 格:¥电议型 号:T71007产 地:中国大陆
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T70443R 93274;化合物 R 93274R 93274
R 93274 is a radioiodinated 5-HT2A receptor antagonist.
价 格:¥电议型 号:T70443产 地:中国大陆