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T73466Pulixin;化合物 PulixinPulixin
Pulixin inhibits FREP1 binding to P. falciparum-infected cell lysate, obstructs parasite transmission to mosquitoes with an EC50 of 11 ?M, and impedes asexual-stage P. falciparum proliferation with an EC50 of 47 nM [1].
价 格:¥电议型 号:T73466产 地:中国大陆
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T73465Goitrin;化合物 GoitrinL-5-Vinyl-2-thiooxazolidone|||(S)-Goitrin|||(S)-Goitrin ; L-5-Vinyl-2-thiooxazol
Goitrin ((S)-Goitrin), formed through glucosinolate-myrosinase reactions, serves as a potent inhibitor of thyroid peroxidase, thereby hindering the thyroid´s utilization of iodine. Additionally, it demonstrates anti-influenza virus (H1N1) activity.
价 格:¥电议型 号:T73465产 地:中国大陆
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T73463NX-2127;化合物NX-2127NX2127|||NX 2127;NX2127|||NX 2127
NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative activity and inhibits the proliferation of BTKC481S mutant TMD8 cells.NX-2127 potently catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) at 25 nM and 54 nM, respectively. NX-2127 is associated with the immune system, stimulating T cell activation and increasing IL-2 production in primary human T cells.
价 格:¥电议型 号:T73463产 地:中国大陆
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T73462MK-8189;化合物 MK-8189MK-8189
MK-8189 is a potent, orally active, and selective inhibitor of Phosphodiesterase 10A (PDE10A), exhibiting a K i value of 29 pM. It has potential applications in the research of schizophrenia.
价 格:¥电议型 号:T73462产 地:中国大陆
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T73461BAY-805;BAY-805BAY-805
BAY-805 is a selective inhibitor of ubiquitin-specific protease USP21 . BAY-805 has high selectivity for deubiquitinating enzyme (DUB) targets, kinases, proteases and other common target enzymes [1] .
价 格:¥电议型 号:T73461产 地:中国大陆
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T73460DDO3711;化合物 DDO3711DDO3711
DDO3711, a PP5-recruiting phosphatase recruitment chimera (PHORC), is created by chemically linking an apoptosis signal-regulated kinase 1 (ASK1) inhibitor with a PP5 activator. This compound selectively targets ASK1 (IC50=164.1 nM) over ASK2 (IC50 >20 μM), effectively dephosphorylating p-ASK1 T838 through PP5 recruitment. Exhibiting ASK1-dependent antiproliferative properties, DDO3711 demonstrates anti-cancer activity, making it a promising agent for research into the abnormal phosphorylation o
价 格:¥电议型 号:T73460产 地:中国大陆
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T7346Lodenafil;羟基豪莫西地那非Hydroxyhomosildenafil;Hydroxyhomosildenafil|||羟基豪莫西地那非
Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)
价 格:¥电议型 号:T7346产 地:中国大陆
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T73346SC 34301;化合物 SC 34301Enisoprost;Enisoprost
SC 34301 (Enisoprost), a potent and orally active prostaglandin E1 (PGE1) analog, significantly enhances survival rates and reduces bacterial translocation in burned mice.
价 格:¥电议型 号:T73346产 地:中国大陆
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T73333OICR12694;化合物 OICR12694JNJ-65234637;JNJ-65234637
OICR12694 (JNJ-65234637) is an orally active inhibitor of B cell lymphoma 6 (BCL6) [1] .
价 格:¥电议型 号:T73333产 地:中国大陆
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T72346KRAS G12C inhibitor 20;化合物 KRAS G12C inhibitor 20KRAS G12C inhibitor 20
KRAS G12C inhibitor 20 is a KRAS G12C inhibitor.
价 格:¥电议型 号:T72346产 地:中国大陆
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T7208AMD 3465 hexahydrobromide;化合物AMD 3465 hexahydrobromideGENZ-644494 (hexahydrobromide);GENZ-644494 (he
AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.
价 格:¥电议型 号:T7208产 地:中国大陆
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T71656ATB-346, (S)-;化合物 ATB-346, (S)-ATB-346, (S)-
ATB-346, (S)-, is the S form of ATB-346. ATB-346 is a novel hydrogen sulfide-releasing anti-inflammatory drug which induces apoptosis of human melanoma cells and inhibits melanoma development in vivo.
价 格:¥电议型 号:T71656产 地:中国大陆
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T7152Ravuconazole;雷夫康唑BMS-207147|||ER-30346;立福康唑|||雷夫康唑|||BMS-207147|||ER-30346
Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.
价 格:¥电议型 号:T7152产 地:中国大陆
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T71346MS4;化合物 MS4MS4
MS4 is a novel glucocorticoid receptor (GR) agonist with anti-inflammatory activity and displaying reduced impact on islets.
价 格:¥电议型 号:T71346产 地:中国大陆
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T71229NA 0346;化合物 NA 0346NA 0346
NA 0346 is a derivative of SF 2370 that shows long lasting antihypertensive action as well as potent protein kinases inhibitory activity.
价 格:¥电议型 号:T71229产 地:中国大陆
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T70546HI-346;化合物 HI-346HI-346
HI-346 is a potent inhibitor of multidrug-resistant human immunodeficiency virus-1 (HIV-1).
价 格:¥电议型 号:T70546产 地:中国大陆
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T70346TOP1362;化合物 TOP1362TOP1362
TOP1362 is a Narrow Spectrum Kinase Inhibitors Demonstrate Promise for the Treatment of Dry Eye Disease and Other Ocular Inflammatory Disorders. TOP1362 strongly inhibited the kinase targets p38α, Syk, Src, and Lck, blocked the rise in p38α expression in hyperosmolar Chang cells, and potently reduced inflammatory cytokine release in cellular models of innate and adaptive immunities. In the EIU model, TOP1362 dose-dependently attenuated the LPS-induced rise in inflammatory cell infiltration and o
价 格:¥电议型 号:T70346产 地:中国大陆
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T69973PF-04363467 HCl;化合物 PF-04363467 HClPF-04363467 HCl
PF-04363467 HCl is a selective dopamine D3/D2 receptor antagonist.
价 格:¥电议型 号:T69973产 地:中国大陆
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T69357AL-34662;化合物 AL-34662AL-34662
AL-34662 is a serotonin-2 receptor agonist with antihypertensive action. AL-34662 has a high-affinity for the 5-HT2 receptor and may potentially lead mobilization of [Ca2+]i in h-CM and h-TM cells leading to a decrease in ocular pressure.
价 格:¥电议型 号:T69357产 地:中国大陆
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T69346A-357300;化合物 A-357300A-357300
A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM. Methionine aminopeptidase 2 inhibition is an effective treatment strategy for neuroblastoma in preclinical models.
价 格:¥电议型 号:T69346产 地:中国大陆