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  • T68581AP23464；化合物 AP23464AP23464

    AP23464 is a potent adenosine 5´-triphosphate (ATP)-based inhibitor of Src and Abl kinases, displays antiproliferative activity against a human CML cell line and Bcr-Abl-transduced Ba/F3 cells (IC(50) = 14 nM. AP23464 ablates Bcr-Abl tyrosine phosphorylation, blocks cell cycle progression, and promotes apoptosis of Bcr-Abl-expressing cells. Biochemical assays with purified glutathione S transferase (GST)-Abl kinase domain confirmed that AP23464 directly inhibits Abl activity. Importantly,

    价 格：￥电议型 号：T68581产 地：中国大陆

  • T673462-(3,4-Dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-4H-chromen-4-one；化合物 2-(3,4-Dimethoxyphenyl)-3-hydro

    2-(3,4-Dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-4H-chromen-4-one is a useful organic compound for research related to life sciences and the catalog number is T67346.

    价 格：￥电议型 号：T67346产 地：中国大陆

  • T65346(2R,3R,4S,5R)-2-(6-(Benzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol；化合物 (2R,3R

    (2R,3R,4S,5R)-2-(6-(Benzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is a natural product for research related to life sciences. The catalog number is T65346 and the CAS number is 4294-16-0.

    价 格：￥电议型 号：T65346产 地：中国大陆

  • T64346DDAC；化合物 DDACQuaternium 12；Quaternium 12

    DDAC (Quaternium 12), also known as Didecyldimethylammonium chloride, is a dialkyl-quaternary ammonium compound widely utilized in various products due to its bactericidal, virucidal, and fungicidal characteristics.

    价 格：￥电议型 号：T64346产 地：中国大陆

  • T63640CCG-273463；化合物 CCG-273463CCG-273463

    CCG-273463 is a potent, covalent, selective inhibitor of GRK5 (IC50: 9 nM). CCG-273463 can be used to study heart failure, hypertrophic cardiomyopathy and cancer.

    价 格：￥电议型 号：T63640产 地：中国大陆

  • T63469RIPK1-IN-8；化合物 RIPK1-IN-8RIPK1-IN-8

    RIPK1-IN-8 is an aminoimidazolopyridine and is a selective and potent inhibitor of RIPK1 (IC50: 4 nM).RIPK1-IN-8 has research potential in inflammatory diseases.

    价 格：￥电议型 号：T63469产 地：中国大陆

  • T63468RET-IN-14；化合物 RET-IN-14RET-IN-14

    RET-IN-14 is a potent inhibitor of RET, capable of acting on RET (WT) (IC50 < 0.51 nM), RET (G810R) (IC50: 9.3 nM), RET (V804M) (IC50: 1.3 nM), BTK (C481S) (IC50: 9.2 nM) and BTK (C481S) (IC50 : 15 nM). RET-IN-14 exhibits potential for tumor studies.

    价 格：￥电议型 号：T63468产 地：中国大陆

  • T63467hCAII-IN-5；化合物 hCAII-IN-5hCAII-IN-5

    hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 ?M [1].

    价 格：￥电议型 号：T63467产 地：中国大陆

  • T63464ERCC1-XPF-IN-1；化合物 ERCC1-XPF-IN-1ERCC1-XPF-IN-1

    ERCC1-XPF-IN-1 is a potent, high-affinity inhibitor of ERCC1-XPF (IC50: 0.49 μM). ERCC1-XPF-IN-1 inhibits the removal of CPDs, reduces the toxicity of cyclophosphamide to colorectal cancer cells, enhances the cytotoxic effects of UV radiation, and impedes DNA repair.

    价 格：￥电议型 号：T63464产 地：中国大陆

  • T63462INSCoV-601I(1)；化合物 INSCoV-601I(1)INSCoV-601I(1)

    INSCoV-601I(1) is a potent Mpro(3CLpro) inhibitor. Proteases (PLpro and 3CLpro) are associated with viral transcription and replication. INSCoV-600I(1) has shown research potential against SARS-CoV-2 infection.

    价 格：￥电议型 号：T63462产 地：中国大陆

  • T63461INSCoV-600K(1)；化合物 INSCoV-600K(1)INSCoV-600K(1)

    INSCoV-600K(1) is a potent Mpro(3CLpro) inhibitor. Proteases (PLpro and 3CLpro) are associated with viral transcription and replication. INSCoV-600K(1) has shown research potential against SARS-CoV-2 infection.

    价 格：￥电议型 号：T63461产 地：中国大陆

  • T63460Tropesin；化合物 TropesinTropesin

    Tropesin is a non-steroidal anti-inflammatory agent (NSAIA) that has inhibitory effects on the growth of Xylaria green.

    价 格：￥电议型 号：T63460产 地：中国大陆

  • T6346WYE-132；化合物WYE-125132WYE 125132|||WYE125132|||WYE-125132；WYE 125132|||WYE125132|||WYE-125132

    WYE-125132 (WYE-132 (WYE-125132)) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.

    价 格：￥电议型 号：T6346产 地：中国大陆

  • T63346TRK-IN-18；化合物 TRK-IN-18TRK-IN-18

    TRK-IN-18 is a potent inhibitor of TRK. Among them are promyosin-related kinases (Trks), a family of receptor tyrosine kinases activated by neurotrophic factors, a group of soluble growth factors containing nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophic factor-3 (NT-3), and neurotrophic factor-4/5 (NT-4/5). 18 exhibits potential for the study of cancer diseases.

    价 格：￥电议型 号：T63346产 地：中国大陆

  • T62346Neuraminidase-IN-7；化合物 Neuraminidase-IN-7Neuraminidase-IN-7

    Neuraminidase-IN-7 (compound 4b), a thiophene derivative, is a potent inhibitor of neuraminidase (IC50: 0.03 μM). -Neuraminidase-IN-7 has potential for influenza studies.

    价 格：￥电议型 号：T62346产 地：中国大陆

  • T61564PF-03463275；化合物PF-03463275PF-3463275；PF-3463275

    PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS permeability and may be used to ameliorate cognitive deficits associated with schizophrenia.

    价 格：￥电议型 号：T61564产 地：中国大陆

  • T61346Ph-Ph+；化合物 Ph-Ph+Ph-Ph+

    Ph-Ph+ is a hemiprotonic compound derived from the dimerization of phenanthroline (ph). It exhibits remarkable antitumor, antibacterial, and antifungal properties [1].

    价 格：￥电议型 号：T61346产 地：中国大陆

  • T61047JMI-346；化合物 JMI-346JMI-346

    JMI-346 can be used as an anti-malarial agent that inhibits the P. falciparum strains CQS (3D7) and CQR (RKL-9) growth with IC50 values of 13 μM and 33 μM. JMI-346 is a potent inhibitor of Plasmodium falciparum falcipain-2 protease (PfFP-2) [1].

    价 格：￥电议型 号：T61047产 地：中国大陆

  • T61035CBR-3465；化合物 CBR-3465CBR-3465

    CBR-3465 is an inhibitor of mycobacterium tuberculosis (Mtb) type II NADH dehydrogenase. The MIC of CBR-3465 against Mtb is 0.16 μM [1].

    价 格：￥电议型 号：T61035产 地：中国大陆

  • T60346PDE4-IN-10；化合物 PDE4-IN-10PDE4-IN-10

    PDE4-IN-10 (compound 7a) is a potent inhibitor of PDE4, with an IC 50 of 7.01 μM for PDE4B. PDE4-IN-10 exhibits selectivity, microsomal stability, inhibition of TNF-α and no major toxicities in vitro [1].

    价 格：￥电议型 号：T60346产 地：中国大陆

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