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T79405PARP1-IN-15;化合物 PARP1-IN-15PARP1-IN-15
PARP1-IN-15 (Compound 6) is a PARP1 inhibitor that also inhibits tankyrase (TNKS) and promotes DNA double-strand breaks, leading to tumor cell apoptosis. It exhibits anti-cancer activity in triple-negative breast cancer (TNBC) cells and patient-derived organoids, making it useful for TNBC research, including cases with or without BRCA1 mutations [1].
价 格:¥电议型 号:T79405产 地:中国大陆
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T7860SM-324405;化合物SM 324405SM 324405;SM 324405
SM-324405 is an agonist of TLR7.
价 格:¥电议型 号:T7860产 地:中国大陆
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T78405Cyanine5 NHS ester iodide;化合物 Cyanine5 NHS ester iodideCyanine5 NHS ester iodide
Cyanine5 NHS ester iodide is a red-fluorescing dye that labels amino groups in peptides, proteins, and oligonucleotides [1].
价 格:¥电议型 号:T78405产 地:中国大陆
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T78341Human IgG1 (F405L) kappa, Isotype Control;化合物 Human IgG1 (F405L) kappa, Isotype ControlHuman IgG1 (F
Human IgG1 (F405L) kappa Isotype Control is a chimeric human-mouse monoclonal antibody serving as an isotype control for the human IgG1 (F405L)κ antibody.
价 格:¥电议型 号:T78341产 地:中国大陆
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T77405Enfortumab;恩诺单抗Enfortumab
Enfortumab is a monoclonal antibody against Nectin-4.Enfortumab can be used to synthesize antibody-drug couplings (enfortumab vedotin) and can also be used in conjunction with platinum compounds to study uroepithelial cancers.
价 格:¥电议型 号:T77405产 地:中国大陆
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T76405[D-Trp2,7,9] Substance P;化合物 [D-Trp2,7,9] Substance P[D-Trp2,7,9] Substance P
[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist that exhibits inhibitory affinities (K_i values) of 1 μM for NK-1, 1.3 μM for NK-2, and approximately 9 μM for NK-3 receptors [1].
价 格:¥电议型 号:T76405产 地:中国大陆
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T75405GlcNAc kinase (EcNagK);化合物 GlcNAc kinase (EcNagK)GlcNAc kinase (EcNagK)
N-Acetylglucosamine kinase (EcNagK), a key enzyme in GlcNAc metabolism, catalyzes the transfer of the gamma-phosphoryl group from ATP to the hydroxyl group at the C-6 position of GlcNAc, producing GlcNAc-6-P [1].
价 格:¥电议型 号:T75405产 地:中国大陆
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T74405PEG2000-C-DMG;化合物 PEG2000-C-DMGPEG2000-C-DMG
PEG2000-C-DMG, a pegylated lipid, facilitates the creation of Onpattro, a hepatically targeted investigational RNAi therapeutic. This agent effectively decreases the synthesis of both mutant and wild-type transthyretin by precisely targeting the 3′ untranslated region of transthyretin mRNA [1] [2].
价 格:¥电议型 号:T74405产 地:中国大陆
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T74059Targaprimir-96 TFA;化合物 Targaprimir-96 TFATargaprimir-96 TFA
Targaprimir-96 TFA, a potent inhibitor of microRNA-96 (miR-96) processing, selectively reduces miR-96 production in cancer cells, thereby inducing apoptosis. This compound exhibits low nanomolar affinity binding to primary miR-96 (pri-miR-96), targeting it specifically in breast cancer cells while remaining inactive in normal breast cells [1].
价 格:¥电议型 号:T74059产 地:中国大陆
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T74056epi-Aszonalenin A;化合物 epi-Aszonalenin Aepi-Aszonalenin A
Epi-Aszonalenin A, a benzodiazepine fungal metabolite initially derived from Aspergillus novofumigatus, functions as a psychoactive agent [1].
价 格:¥电议型 号:T74056产 地:中国大陆
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T74052Polyinosinic-polycytidylic acid potassium;化合物 Polyinosinic-polycytidylic acid potassiumPolyinosinic-
Polyinosinic-polycytidylic acid potassium (Poly(I:C) potassium), a synthetic double-stranded RNA analog, serves as an agonist for toll-like receptor 3 (TLR3) and retinoic acid-inducible gene I (RIG-I)-like receptors (RIG-I and MDA5), offering applications in immunotherapy. Its sodium variant enhances both innate and adaptive immune responses when used as a vaccine adjuvant, and is instrumental in modifying the tumor microenvironment. Additionally, Poly(I:C) potassium can directly induce apoptosi
价 格:¥电议型 号:T74052产 地:中国大陆
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T74051Pyridinium bisretinoid A2E;化合物 Pyridinium bisretinoid A2EPyridinium bisretinoid A2E
Pyridinium bisretinoid A2E (A2E)is an initiator of blue-light-induced apoptosis . Photoactivation of Pyridinium bisretinoid A2E mediates autophagy and the production of reactive oxygen species [1] [2] .
价 格:¥电议型 号:T74051产 地:中国大陆
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T74050Allyl methyl trisulfide;化合物 Allyl methyl trisulfideAllyl methyl trisulfide
Allyl methyl trisulfide, a volatile organic compound found in garlic (Allium sativum L.) essential oil, exhibits antibacterial, antioxidant, and antitumor activities [1].
价 格:¥电议型 号:T74050产 地:中国大陆
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T7405Piperidolate二苯哌酯二苯哌酯|||哌立度酯
Piperidolate inhibits intestinal cramp induced by acetylcholine
价 格:¥电议型 号:T7405产 地:中国大陆
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T73017ONO-0740556;化合物 ONO-0740556ONO-0740556
ONO-0740556 is a potent agonist of the Gi-coupled human lysophosphatidic acid receptor 1 (LPA1), exhibiting an EC50 value of 0.26 nM.
价 格:¥电议型 号:T73017产 地:中国大陆
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T72146Loxoprofenol-SRS tromethamine;化合物 Loxoprofenol-SRS tromethamineHR1405–01;HR1405–01
Loxoprofenol-SRS tromethamine (HR1405-01), the active metabolite of Loxoprofen, represents a non-steroidal anti-inflammatory drug (NSAID) designed for intravenous administration. It is recognized for its enhanced anti-inflammatory and analgesic properties, positioning it as a safe option within its class.
价 格:¥电议型 号:T72146产 地:中国大陆
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T71405Domitroban;化合物 DomitrobanDomitroban
Domitroban, also known as S-145, is a thromboxane (Tx) A2-receptor antagonist with partial agonistic activity in vascular smooth muscle.
价 格:¥电议型 号:T71405产 地:中国大陆
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T70405L-744832;化合物 L-744832L-744832
L-744832, also known as L-744,832, is a potent Farnesyltransferase inhibitor with potential anticancer activity.
价 格:¥电议型 号:T70405产 地:中国大陆
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T69907EML-405;化合物 EML-405EML-405
EML-405 is a small-molecule inhibitor of SPIN1 ( Kd of 14 uM).
价 格:¥电议型 号:T69907产 地:中国大陆
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T69405Metformin embonate;化合物 Metformin embonateMetformin embonate
Metformin embonate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
价 格:¥电议型 号:T69405产 地:中国大陆