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T6325PCI-34051N-羟基-1-(4-甲氧基苄基)-1H-吲哚-6-甲酰胺N-羟基-1-(4-甲氧基苄基)-1H-吲哚-6-甲酰胺|||PCI 34051
PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).
价 格:¥电议型 号:T6325产 地:中国大陆
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T63141ASP-4058 hydrochloride;化合物 ASP-4058 hydrochlorideASP-4058 hydrochloride
ASP-4058 hydrochloride is a selective, orally active secondary agonist of sphingosine phosphate receptors 1 and 5 (S1P1 and S1P5). ASP-4058 hydrochloride is safe and improves experimental autoimmune encephalomyelitis in mice.
价 格:¥电议型 号:T63141产 地:中国大陆
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T6258Zibotentan;化合物ZibotentanZD4054;ZD4054
Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.
价 格:¥电议型 号:T6258产 地:中国大陆
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T62405KDM1/CDK1-IN-1;化合物 KDM1/CDK1-IN-1KDM1/CDK1-IN-1
KDM1/CDK1-IN-1 (compound 4) is a potent inhibitor of KDM1 (IC50: 0.096 μM) and CDK1 (IC50: 0.078 μM). kDM1/CDK1-IN-1 blocks the cell cycle of HOP-92 cells in G2/M phase and induces apoptosis. KDM1/CDK1-IN-1 is highly cytotoxic to CCRF-CEM cells (IC50: 16.34 μM), HOP-92 cells (IC50: 3.45 μM) and Hep-G2 cells (IC50: 7.79 μM).
价 格:¥电议型 号:T62405产 地:中国大陆
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T6222PFI-1;化合物PFI1PF-6405761|||PFI 1|||PFI1;PF-6405761|||PFI 1|||PFI1
PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.
价 格:¥电议型 号:T6222产 地:中国大陆
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T61405LSD1-IN-14;化合物 LSD1-IN-14LSD1-IN-14
LSD1-IN-14, a powerful and specific inhibitor of LSD1 (with an IC50 value of 0.89 μM), effectively suppresses the growth of A549 and THP-1 cells and promotes the apoptosis of tumor cells [1].
价 格:¥电议型 号:T61405产 地:中国大陆
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T61116NSC405640;化合物 NSC405640NSC405640
NSC405640 is a highly effective compound that inhibits the interaction between MDM2 and p53 proteins. Furthermore, it can restore the structural integrity of p53 molecules affected by mutations. Notably, NSC405640 exhibits selectivity in inhibiting the growth of cell lines that possess the normal, unmutated form of the p53 protein [1].
价 格:¥电议型 号:T61116产 地:中国大陆
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T60405GSK-3036656 free base;化合物 GSK3036656GSK656 HCl|||GSK 3036656|||GSK656|||GSK-3036656|||GSK-656|||GSK
GSK656 (GSK3036656) shows potent inhibition of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS) (IC50 = 0.20 μM) which has potential for the treatment of tuberculosis [1].
价 格:¥电议型 号:T60405产 地:中国大陆
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T60048WAY-640509;化合物WAY-640509WAY-640509
WAY-640509 is a glucocerebrosidase inhibitor.
价 格:¥电议型 号:T60048产 地:中国大陆
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T5405BI-1347;化合物BI-1347BI-1347
BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.
价 格:¥电议型 号:T5405产 地:中国大陆
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T4760KSD 2405;3-羟基苯甲醇3-Hydroxybenzyl alcohol;3-羟基苯甲醇|||3-Hydroxybenzyl alcohol
KSD 2405 (3-Hydroxybenzyl alcohol) is a hydroxybenzyl alcohol that is phenol substituted at position C-3 by a hydroxymethyl group. It is a pink or beige to brown crystalline powder, soluble in water.
价 格:¥电议型 号:T4760产 地:中国大陆
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T4405Ceftibuten dihydrate;头孢布烯二水合物Sch-39720 dihydrate;头孢布烯二水合物|||Sch-39720 dihydrate
Ceftibuten dihydrate (Sch-39720 dihydrate) is the dihydrate form of ceftibuten, and is a third-generation cephalosporin with antibacterial activity.
价 格:¥电议型 号:T4405产 地:中国大陆
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T40599HO-PEG5-CH2COOH;HO-PEG5-CH2COOHHO-PEG5-CH2COOH;HO-PEG5-CH2COOH
HO-PEG5-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40599产 地:中国大陆
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T40598Norethindrone acetate醋酸炔诺酮19-Norethindroneacetate
Norethindrone acetate (19-Norethindroneacetate) is an oestrogen with inhibitory effects on adolescent menstruation and hepatic adenomas and is often used in combination with progestins in the study of endometriosis.
价 格:¥电议型 号:T40598产 地:中国大陆
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T40597Chloro-PEG5-chloride;Chloro-PEG5-chlorideChloro-PEG5-chloride;Chloro-PEG5-chloride
Chloro-PEG5-chloride is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40597产 地:中国大陆
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T40596Tasisulam sodium;Tasisulam sodiumLY 573636 sodium|||Tasisulam sodium;LY 573636 sodium|||Tasisulam so
Tasisulam is an anti-cancer compound that induces apoptosis through the intrinsic pathway, leading to the release of cytochrome c and caspase-dependent cell death. Additionally, tasisulam inhibits mitotic progression and triggers vascular normalization.
价 格:¥电议型 号:T40596产 地:中国大陆
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T40595Rubiayannone A;Rubiayannone ARubiayannone A
Rubiayannone A is an anthraquinone glycoside with an antiplatelet aggregation activity.
价 格:¥电议型 号:T40595产 地:中国大陆
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T40594iHCK-37;iHCK-37iHCK-37|||ASN05260065;iHCK-37|||ASN05260065
iHCK-37 (ASN05260065) is a high-potency, selective inhibitor of Hck with a Ki value of 0.22 μM. It effectively inhibits HIV-1 viral replication, exhibiting an EC50 value of 12.9 μM. Primarily employed in chronic myeloid leukemia (CML) research, iHCK-37 demonstrates promising potential for studying and understanding this disease.
价 格:¥电议型 号:T40594产 地:中国大陆
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T405935-FAM-Alkyne;5-FAM-Alkyne5-FAM-Alkyne
5-FAM-Alkyne is a highly selective and sensitive fluorescent biosensor designed for detecting alkaline phosphatase (ALP).
价 格:¥电议型 号:T40593产 地:中国大陆
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T40590NY-ESO-1 (87-111);NY-ESO-1 (87-111)NY-ESO-1 (87-111)
NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide that interacts with various HLA-DR and HLA-DP4 molecules, inducing activation of CD4+ T cells with Th1-type and Th-2/Th0-type responses, when presented in conjunction with HLA-DR and HLA-DP4 molecules.
价 格:¥电议型 号:T40590产 地:中国大陆