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T60122AldometanibCompoundIA47
Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib prevents FBP from binding to v-ATPase-associated aldolase and activates lysosomal AMPK. Aldometanib can be used for the research of metabolic homeostasis [1].
价 格:¥电议型 号:T60122产 地:中国大陆
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T12188NB-360Inhibitor,BACE,NB 360,β-Secretase,inhibit,NB-360,NB360,Beta-secretase
NB-360 is a potent and brain-penetrable inhibitor of BACE1 and BACE2 with IC50s of 5, 5, and 6 nM for mouse and human BACE1 and BACE2. NB-360 exhibits excellent selectivity over the related aspartyl proteases pepsin, cathepsin E, and cathepsin D.
价 格:¥电议型 号:T12188产 地:中国大陆
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T15608Jarin-1Jarin 1,Jarin1
Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM). Jarin-1 specific suppresses bioactive JA biosynthesis in Arabidopsis and other plants.
价 格:¥电议型 号:T15608产 地:中国大陆
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TQ0060LY2857785Cyclin dependent kinase,LY 2857785,CDK,Apoptosis,LY2857785,Inhibitor,inhibit,LY-2857785
LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).
价 格:¥电议型 号:TQ0060产 地:中国大陆
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T9608KL201KL201,CRY1,Inhibitor,Per2-dLuc,FBXL3,inhibit,clock,KL 201,circadian,cryptochrome,KL-201
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues[1].
价 格:¥电议型 号:T9608产 地:中国大陆
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T6602Naratriptan hydrochlorideNaratriptan hydrochloride,Inhibitor,GR-85548A,Naratriptan,5-HT Receptor,5-h
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulatio
价 格:¥电议型 号:T6602产 地:中国大陆
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T17255WJ460WJ-460,WJ460
WJ460 is an effective inhibitor of myoferlin. WJ460 exerts anti-metastatic activity in breast cancer cells.
价 格:¥电议型 号:T17255产 地:中国大陆
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T9760IC 86621ATP,Buchwald-Hartwig amination,Inhibitor,IC-86621,IC86621,IC 86621,DSB,antitumor,inhibit,Apo
IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break(DSB)-induced antitumor activity with an EC50 of 68 ?M for DNA-PK mediated cellular DSB repair.
价 格:¥电议型 号:T9760产 地:中国大陆
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T60027(+)-OSU 61624((5cyclopropyl3methyl1((methylsulfonyl)methyl)1Hpyrazol4yl)oxy)2,6dimethylbenzonitrile,
4-((5-cyclopropyl-3-methyl-1-((methylsulfonyl)methyl)-1H-pyrazol-4-yl)oxy)-2,6-dimethylbenzonitrile is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.
价 格:¥电议型 号:T60027产 地:中国大陆
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T60033SBI993SBI993
SBI993 is an analog of SBI-477 and can be used as a biomarker to confirm the expected action of MondoA target gene expression in vivo. SBI993 reduces muscle TAG levels and hepatic steatosis.
价 格:¥电议型 号:T60033产 地:中国大陆
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T60060ACSS2-IN-2
ACSS2-IN-2 is an inhibitor of acyl-CoA synthetase short-chain family member 2 (ACSS2). ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer.
价 格:¥电议型 号:T60060产 地:中国大陆
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T12360para-Nitroblebbistatin
para-Nitroblebbistatin is a non-cytotoxic, fluorescent, photostable and specific Myosin II inhibitor. para-Nitroblebbistatin can be used in the study of the special role of myosin II in developmental, physiological,, and cell biological studies.
价 格:¥电议型 号:T12360产 地:中国大陆
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T60094SU 4981
SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.
价 格:¥电议型 号:T60094产 地:中国大陆
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T60095CCF0058981CCF0058981
CCF0058981 (CCF981) is a 3-chlorophenyl analogue which is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CL pro ) with an IC 50 of 19 nM. CCF0058981 has antiviral efficacy and has the potential for COVID-19 research [1].
价 格:¥电议型 号:T60095产 地:中国大陆
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TN6088tricoumaroyl spermidinetricoumaroyl spermidine
Tricoumaroyl spermidine was discovered as unique tea (Camellia sinensis) flower metabolites.
价 格:¥电议型 号:TN6088产 地:中国大陆
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T31602Ecopipam
Ecopipam is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam can be used for the research of schizophrenia, cocaine addition, and obesity.
价 格:¥电议型 号:T31602产 地:中国大陆
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T86022-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE2 CHLOROMETHYL 1,1 DIOXO 1,2
2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).
价 格:¥电议型 号:T8602产 地:中国大陆
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T60103N6-(p-Hydroxyphenethyl)-Adenosine)N6 (P HYDROXYPHENETHYL) ADENOSINE),N6(PHYDROXYPHENETHYL)ADENOSINE)
N6-(p-Hydroxyphenethyl)-Adenosine) is an adenosine analogue.
价 格:¥电议型 号:T60103产 地:中国大陆
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T60130USP5-IN-1USP5IN1
USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor, which binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate [1].
价 格:¥电议型 号:T60130产 地:中国大陆