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产品数:86101
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T6S1879Indaconitineinhibit,Inhibitor,Indaconitine,15-Deoxyaconitine
Indaconitine is a natural product from Aconitum hemsleyanum PRITZ.
价 格:¥电议型 号:T6S1879产 地:中国大陆
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T6S0234ToosendaninToosendanin,Inhibitor,inhibit
1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin is an effective insecticide for Ae.
价 格:¥电议型 号:T6S0234产 地:中国大陆
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T6S0071FraxinelloneHIFs,Hypoxia-inducible factors,Fraxinellone,HIF-PH,STAT,Inhibitor,inhibit,HIF/HIF Prolyl
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding-deterrent activity, inhibition of growth, and larvicidal activity. 3. Fraxinellone has effect in the midgut metabolism of Mythimna separata (M. separata), via protease (especially the weak alkaline trypsin-like enzyme), carboxylesterase and glutathione S-transferase.
价 格:¥电议型 号:T6S0071产 地:中国大陆
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T6S2116Ginkgolic acid C17:1Phosphatase and tensin homolog,PTEN,Phosphatase,Inhibitor,MMAC1,inhibit,Ginkgoli
1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.
价 格:¥电议型 号:T6S2116产 地:中国大陆
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T6S1418Praeruptorin CCa2+ channels,Ca channels,Calcium Channel,Praeruptorin C,Inhibitor,inhibit
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors and regulating the Bcl-2 family. 3. Praeruptorin C can reduce vascular hypertrophy in isolated rat hypertrophied smooth muscle cells, and this is associated with improvement of smooth muscle cells [Ca2+]i level, nitric oxide content and cellular signal transdution of protein kina
价 格:¥电议型 号:T6S1418产 地:中国大陆
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T6S1027TussilagoneTussilagone,anti-inflammatory,puncture,dextran,murine,ligation,colitis,cecal,inhibit,sulp
1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human colon cancer. 3. Tussilagone has anti-oxidant and anti-inflammatory activities, may be an effective oxygenase-1 inducer and a valuable compound for modulating inflammatory conditions. 4. Tussilagone has potential treatment of neuro-inflammatory diseases through the inhibition of ov
价 格:¥电议型 号:T6S1027产 地:中国大陆
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T6S1699ShogaolInhibitor,Shogaol,Autophagy,inhibit
1. 6-Shogaol has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). 4. 6-Shogaol e
价 格:¥电议型 号:T6S1699产 地:中国大陆
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T6S2122Ginkgolic Acid (C13:0)Inhibitor,inhibit,Bacterial,Ginkgolic Acid (C-13:0),Ginkgolic Acid (C13:0)
1.Ginkgolic acid C13: 0exhibits the highest α-glucosidase inhibitory activity.
价 格:¥电议型 号:T6S2122产 地:中国大陆
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T6S0444Salvianolic acid AMatrix metalloproteinases,Salvianolic acid A,inhibit,MMP,Inhibitor
Salvianolic acid A could protect the blood brain barrier through inhibition of matrix metallopeptidase 9 (MMP-9) and anti-inflammation.
价 格:¥电议型 号:T6S0444产 地:中国大陆
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T6S2356Corynolineinhibit,Corynoline,Inhibitor,Cholinesterase (ChE),Keap1-Nrf2
1. Corynoline is an acetylcholinesterase inhibitor.
价 格:¥电议型 号:T6S2356产 地:中国大陆
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T6S0141CorylinBacterial,Antibiotic,inhibit,Inhibitor,Corylin
Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.
价 格:¥电议型 号:T6S0141产 地:中国大陆
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T6S0117Avicularininhibit,inflammation,COX,Peroxisome proliferator-activated receptors,GLUT,oxidative stress
1. Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. 2. Avicularin inhibits the accumulation of the intracellular lipids by decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase.
价 格:¥电议型 号:T6S0117产 地:中国大陆
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T6S1768Narcissininhibit,Antioxidant Activity,Narcissin,Inhibitor
1. Narcissoside, with synergism of B.flavum flavonoid and rutin, could be responsible for stronger protection against mitochondrial induced oxidative stress.
价 格:¥电议型 号:T6S1768产 地:中国大陆
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T6S1302CarnosolRibosomal S6 Kinase (RSK),Keap1-Nrf2,Endogenous Metabolite,S6K,inhibit,Carnosol,Inhibitor
Carnosol has anti-oxidative, anti-inflammatory, antiproliferative and apoptosis inducing properties. Carnosol enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. 3. Carnosol may as a novel agonist of TRPA1 with an EC5 value of 12.46 μM.
价 格:¥电议型 号:T6S1302产 地:中国大陆
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T6S1487Ginsenoside Rg5Nuclear factor-κB,Inhibitor,Ginsenoside Rg5,Cyclooxygenase,Ginsenoside Rg 5,NF-κB,COX
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer´s disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. 4. Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasc
价 格:¥电议型 号:T6S1487产 地:中国大陆
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T6S20258-?O-?Acetylharpagideinhibit,Bacterial,8?O?Acetylharpagide,Inhibitor,8 ?O ?Acetylharpagide
1. 8-O-Acetylharpagide has anti-inflammatory activity. 2. 8-O-Acetylharpagide has antibacteria and antiviral activities. 3. 8-O-Acetylharpagide has a biological activity on isolated smooth muscle preparations from guinea pig.
价 格:¥电议型 号:T6S2025产 地:中国大陆
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T6S1966CurculigosideCurculigoside,Janus kinase,NF-κB,JAK,Nuclear factor-κB,Nuclear factor-kappaB,STAT,inhib
1. Curculigoside can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disorders. 2. Curculigoside can promote calcium deposition and increase the levels of ALP and Runx2 in osteoblasts under oxidative stress via anti-oxidative character. 3. Curculigoside possesses potent antioxidant properties against oxidative stress insults. can protect endothelial cells against oxidati
价 格:¥电议型 号:T6S1966产 地:中国大陆
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T6S0095GenkwaninVirus Protease,inhibit,Inhibitor,Genkwanin
1. Genkwanin exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug resistance protein (MDR)-mediated efflux mechanisms.
价 格:¥电议型 号:T6S0095产 地:中国大陆
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T6S0525Farrerolinhibit,Inhibitor,Farrerol
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3. Farrerol inactivates KEAP-1 or activates the Akt, p38 and ERK to facilitate the release of Nrf2 from Keap1 and subsequent reduces the intracellular production of reactive oxygen species via the induction of HO-1 expression. 4. Farrerol has protective effects against H2O2-induced
价 格:¥电议型 号:T6S0525产 地:中国大陆
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T6S0653Linarinarvensis,Linarin,Inhibitor,acetylcholinesterase,inhibit,Mentha,Cholinesterase (ChE)
1. Linarin (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during
价 格:¥电议型 号:T6S0653产 地:中国大陆