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T64603Akt Antibody #9272R;化合物 Akt Antibody #9272RAkt Antibody #9272R
Akt Antibody #9272R is a useful organic compound for research related to life sciences and the catalog number is T64603.
价 格:¥电议型 号:T64603产 地:中国大陆
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T64583Phospho-Akt (Ser473) Antibody #9271R;化合物 Phospho-Akt (Ser473) Antibody #9271RPhospho-Akt (Ser473) An
Phospho-Akt (Ser473) Antibody #9271R is a useful organic compound for research related to life sciences and the catalog number is T64583.
价 格:¥电议型 号:T64583产 地:中国大陆
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T63927KRAS G12C inhibitor 25;化合物 KRAS G12C inhibitor 25KRAS G12C inhibitor 25
KRAS G12C inhibitor 25 is an inhibitor of KRAS G12C. KRAS G12C inhibitor 25 inhibits the SOS1-assisted GDP/GTP exchange activity of KRAS-G12C mutants with an IC50 value of 0.48 nM.
价 格:¥电议型 号:T63927产 地:中国大陆
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T62927HPK1-IN-22;化合物 HPK1-IN-22HPK1-IN-22
HPK1-IN-22 (compound ZYF0033) is a haematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of less than 10 nM for MBP protein-based phosphorylation inhibition. HPK1-IN-22 reduces phosphorylation of SLP76 (serine 376) and promotes anti-cancer immune responses. HPK1-IN-22 inhibits tumor growth and increases intra-tumor infiltration of DCs, NK cells and CD107a+CD8+ T cells, but decreases infiltration of T cells, PD-1+CD8+ T cells, TIM-3+CD8+ T cells and LAG3+CD8+ T cells in a 4T-1 homozygo
价 格:¥电议型 号:T62927产 地:中国大陆
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T62376GNE-9278;化合物 GNE-9278GNE-9278
GNE-9278 is a highly selective NMDAR orthosteric modulator that acts on the GluN1 transmembrane structural domain (TMD).GNE-9278 acts on activated NMDAR and increases peak current and agonist affinity.
价 格:¥电议型 号:T62376产 地:中国大陆
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T61927hDDAH-1-IN-2 sulfate;化合物 hDDAH-1-IN-2 sulfatehDDAH-1-IN-2 sulfate
hDDAH-1-IN-2 is a selective, orally active inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with an excellent profile regarding cell toxicity/viability.
价 格:¥电议型 号:T61927产 地:中国大陆
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T60927Ranimustine;化合物 RanimustineRanimustine
Ranimustine (MCNU) can be used for polycythemia vera and chronic myelogenous leukemia research, which is a nitrosourea alkylating agent [1] [3] [4].
价 格:¥电议型 号:T60927产 地:中国大陆
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T60092CHEMBL1276927;N-[3-(1H-苯并[d]咪唑-2-基)苯基]-3-甲基苯甲酰胺N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide|
CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) shows antibacterial and antiparasitic activities against Chlamydia pneumoniae and Leishmania donovani.
价 格:¥电议型 号:T60092产 地:中国大陆
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T5323Toloxatone托洛沙酮托洛沙酮|||MD 69276
Toloxatone (MD 69276) is a reversible monoamine oxidase A (MAOA) inhibitor.
价 格:¥电议型 号:T5323产 地:中国大陆
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T5207LIT927;化合物LIT-927LIT 927|||LIT-927;LIT 927|||LIT-927
LIT927 (LIT-927) is an orally active CXCL12 neutraligand (Ki: 267 nM for CXCL12 binding to CXCR4).
价 格:¥电议型 号:T5207产 地:中国大陆
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T49274-Guanidinobutanoic acid;4-胍基丁酸4-GBA|||4-Guanidinobutyric acid;4-GBA|||4-胍基丁酸|||4-Guanidinobutyric a
4-Guanidinobutanoic acid (4-GBA) is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been specifically use to human proton coupled amino acid transporters hPAT1.
价 格:¥电议型 号:T4927产 地:中国大陆
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T4354KPT9274;化合物KPT9274KPT-9274|||KPT 9274|||PAK4-IN-1;KPT-9274|||KPT 9274|||PAK4-IN-1
KPT9274 (PAK4-IN-1) is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule.
价 格:¥电议型 号:T4354产 地:中国大陆
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T40927DOTA-tris(tBu)ester NHS ester;DOTA-tris(tBu)ester NHS esterDOTA-tris(tBu)ester NHS ester
DOTA-tris(tBu)ester NHS ester, a derivative of DOTA, serves for the labeling of peptides and antibodies.
价 格:¥电议型 号:T40927产 地:中国大陆
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T40542Sinbaglustat;化合物SinbaglustatACT-519276|||Sinbaglustat|||OGT2378;ACT-519276|||Sinbaglustat|||OGT2378
Sinbaglustat (OGT2378) (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally administered N-alkyl iminosugar that crosses the blood-brain barrier.Sinbaglustat is used for the treatment of lysosomal storage disorders and for the study of central neurodegenerative disorders associated with lysosomal dysfunction. Sinbaglustat is used for the treatment of lysosomal storage disorders and for the study of lysosomal dysf
价 格:¥电议型 号:T40542产 地:中国大陆
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T39927Zeteletinib hemiadipateZeteletinib hemiadipateBOS-172738 hemiadipate|||DS-5010hemiadipate|||Zeteleti
Zeteletinib hemiadipate (BOS-172738; DS-5010) is an orally active compound that functions as a selective inhibitor of RET kinase. It exhibits nanomolar potency against RET and a 300-fold selectivity towards VEGFR2. Notably, Zeteletinib hemiadipate demonstrates exceptional effectiveness against various forms of RET, including the wild type, RET V804M/L gatekeeper mutants, and the oncogenic RET mutation M918T. Additionally, Zeteletinib hemiadipate exerts potent antitumor effects.
价 格:¥电议型 号:T39927产 地:中国大陆
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T39833(Rac)-CP-601927 hydrochloride;(Rac)-CP-601927 hydrochloride(Rac)-CP-601927 hydrochloride
(Rac)-CP-601927 hydrochloride is the racemate form of CP-601927, which is a nicotinic acetylcholine receptor (nAChR) agonist. It exhibits Ki values of 1.2 nM and 102 nM for α4β2 and α3β4 nAChR, respectively.
价 格:¥电议型 号:T39833产 地:中国大陆
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T39681Elomotecan hydrochlorideElomotecan hydrochlorideBN 80927
Elomotecan hydrochloride (BN 80927), a camptothecin analog from the homocamptothecin family (hCPT), is a highly potent inhibitor of both topoisomerases I and II. It demonstrates superior efficacy in reducing the proliferation of various tumor cells compared to other reference anticancer drugs targeting these topoisomerases.
价 格:¥电议型 号:T39681产 地:中国大陆
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T39279L-Hexaguluronic acid;L-古罗糖醛酸五糖L-Hexaguluronic acid
L-Hexaguluronic acid, a linear polysaccharide copolymer, consists of six units of L-guluronic acid (G).
价 格:¥电议型 号:T39279产 地:中国大陆
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T39278L-Pentaguluronic acid;L-古罗糖醛酸五糖L-Pentaguluronic acid
L-Pentaguluronic acid, a linear polysaccharide copolymer, consists predominantly of four units of L-guluronic acid (G).
价 格:¥电议型 号:T39278产 地:中国大陆
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T39277D-Hexamannuronic acid;D-甘露糖醛酸六糖D-Hexamannuronic acid
D-Hexamannuronic acid, an alginate oligomer, is derived from marine brown algae and a restricted group of Gram negative bacteria. This compound serves as a valuable tool for investigating pain and vascular dementia[4].
价 格:¥电议型 号:T39277产 地:中国大陆